Clinical trials: Infertility/Sterility
Polycystic Ovary Syndrome, IVF
Follicular Fluid Raman Shifts and IVF Outcomes
This study intends to collect about 150 cases of follicular fluid samples from PCOS and non-PCOS infertility patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles (in clinical…
- Trial name
- NCT04838535
- Testing
- Raman spectrum
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility, Female
The Role of Erzhi Tiangui Formula in Expected POR Women Undergoing IVF-ET
This randomized controlled trial aims to determine whether Erzhi Tiangui Formula can optimize the reproductive outcomes of elderly patients with expected poor ovarian response, and to provide a new approach to traditional Chinese…
- Trial name
- NCT05698550
- Testing
- Erzhi Tiangui Granule
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Shandong University of Traditional Chinese Medicine
Infertility/Sterility
Markers in Follicular Fluid and in Embryo Culture Medium as a Marker of Oocyte and Embryo Quality
Assessment of the quality of follicular fluid and early embryo via chemical markers.
- Trial name
- NCT03350009
- Where
- Israel
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Infertility
Impact of Reproductive Problems on Couples
Reproduction is in fact the most basic instinct of all living things. The fertility of a woman is both a biological fact and a determinant of gender role in society.
- Trial name
- NCT03365830
- Testing
- FertQol, Beck's Depression Inventory, Beck's Anxiety Inventory
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Infertility
Evaluation of SiD's System for Improving Assisted Reproduction Treatments
According to the WHO, infertility affects 15% of reproductive age couples worldwide. Among the assisted reproductive technologies available for patients with infertility, intracytoplasmic sperm injection (ICSI) has become one of…
- Trial name
- NCT05611164
- Testing
- Software assisted selection of individual spermatozoa for intracytoplasmic sperm injection
- Where
- 2 sites in Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IVF 2.0 Limited
Infertility
Comparison Between hCG and GnRH Agonist for Ovulation Induction in Patients With High Response to IVF Drugs
hCG and GnRH agonist can be used to induce final oocyte maturation and ovulation in IVF cycles. These two approaches will be compared in this study in terms of pregnancy rates and embryological data using patients with…
- Trial name
- NCT00415792
- Testing
- Arvekap, Pregnyl
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eugonia
Infertility
Injection of Hormone to Enhance Implantation in Embryo Transfer After IVF
The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.
- Trial name
- NCT01986374
- Testing
- HCG is introduced
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Servy Massey Fertility Insititute
Infertility, Miscarriage, Recurrent
ANXA5 M2 Haplotyping in IVF Patients and Embryos
This study aims to characterize the association between history of pregnancy complications and M2 carrier status in IVF patients and the utility of M2 haplotype preimplantation genetic testing (PGT) in embryos produced by carrier…
- Conditions
- Infertility, Miscarriage, Recurrent, Pregnancy Complications
- Trial name
- NCT04544462
- Testing
- M2 Test
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Genomic Prediction Inc.
Infertility
Effect of Dehydroepiandrosterone Administration in Patients With Poor Ovarian Response According to the Bologna Criteria
Women with low ovarian reserve typically respond less well to the drugs used to stimulate the ovary during IVF treatment and produce fewer eggs and, as a result, are less likely to fall pregnant either naturally or after…
- Trial name
- NCT02132559
- Testing
- DHEA
- Where
- China
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chinese Medical Association
Infertility, Controlled Ovarian Hyperstimulation
Follicular Steroid Genesis in Controlled Ovarian Stimulation
Serum concentrations of the different hormones involved in follicular steroid genesis during a cycle of controlled ovarian stimulation with recombinant FSH or HMG will be compared in this study.
- Trial name
- ESTEFOL (NCT02738580)
- Testing
- COS with GnRH antagonists and rFSH, COS with GnRH antagonists and HP-HMG
- Where
- Spain
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Overweight, Obesity
3mg Liraglutide for Overweight or Obesity
In this study investigators will investigate the beneficial metabolic sequelae of Liraglutide in patients with obesity or overweight; including changes in vital signs, anthropometric characteristics (weight, body mass index and…
- Conditions
- Overweight, Obesity, Infertility, Female
- Trial name
- NCT03885297
- Testing
- Saxenda, Lifestyle modification, Metabolomics
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Infertility
Comparison of Alternative Embryo Culture Systems
This study will compare two alternative embryo culture systems. Embryos from each patient will be randomly assigned to one of two systems. One group will be cultured conventionally in oil-covered droplets in dishes.
- Trial name
- NCT02028897
- Testing
- Conventional embryo culture, Enclosed embryo culture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bruce Shapiro M.D.
Pain
EMLA and Sterile Water Injections - Pain From Injections
The aim is to study the effect of local anaesthesia (EMLA®) on pain associated with sterile water injections.
- Trial name
- NCT02213185
- Testing
- EMLA patches
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Skövde
Infertility
Intrauterine G-CSF Administration in RIF
Aim of this study is to investigate the effects of intrauterine G-CSF on endometrial thickness, clinical pregnancy rate and live birth rate in a recurrent implantation failure (RIF) group
- Trial name
- G-CSF (NCT03783208)
- Testing
- G-CSF, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Gurgan Clinic
IVF
Speculum Insertion During Embryo Transfer
Lubrication gels are widely used in numerous gynecologic procedures in order to ease the insertion of speculum and visualize the cervix.
- Trial name
- NCT06210451
- Testing
- Sterile water-based gel
- Where
- Israel
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Erectile Dysfunction, Azoospermia
Trial to Evaluate Erectile Function, Fertility and Sperm Count in Male Cyclists Compared to Age Matched Controls
Bicycle riding is associated with related diverse urogenital symptoms ranging from genital numbness to erectile dysfunction (ED).
- Trial name
- NCT00282477
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility, Abnormal Uterine and Vaginal Bleeding, Unspecified
Optimum Misoprostol Dose Prior to Office Hysteroscopy
Misoprostol is an effective agent for cervical priming before office hysteroscopy, vaginal route is the best, optimum dose not yet known.
- Conditions
- Infertility, Abnormal Uterine and Vaginal Bleeding, Unspecified, Recurrent Abortion
- Trial name
- NCT01612065
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia, Local
A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution
This is a Phase 3, randomized, placebo-controlled, double masked, parallel design study in healthy subjects performed in the US.
- Trial name
- NCT04829344
- Testing
- AG-920
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- American Genomics, LLC
Infertility
Variation in Serum Prolactin Levels During IntraCytoplasmic Sperm Injection
The purpose of the study is to determine whether or not stressful conditions such as ovum pick and awaiting Embryo Transfer is associated with significant increase in serum Prolactin (PRL) concentration in some…
- Trial name
- NCT02292953
- Testing
- Serum Prolactin levels
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Infertility (IVF Patients), Clinical Pregnancy After Single Embryo Transfer
Correlation Of Clinical Outcomes After Transfer Of Good-Quality Morphology Embryos In Patients With A Favorable Prognosis And Non-Invasive Preimplantation Genetic Testing For Aneuploidy (NiPGT-A) Results
Non-invasive preimplantation genetic testing for aneuploidy (NiPGT-A) is an emerging approach that analyzes embryonic cell-free DNA (cfDNA) released into the spent culture medium (SCM) to assess chromosomal status without…
- Conditions
- Infertility (IVF Patients), Clinical Pregnancy After Single Embryo Transfer, Embryo Diagnosis and Selection
- Trial name
- NCT07700602
- Where
- Vietnam
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
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