Clinical trials: Infertility/Sterility
Fertility
Serum Levels of Insulin- Like Growth Factor and Fertility
this study will try to determine whether serum levels of insulin like growth factor are higher in fertile women than infertile women.
- Trial name
- NCT00364507
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Male Infertility, Azoospermia
Evaluating the Safety and Clinical Efficacy of the BAIBYS™ System in Intracytoplasmic Sperm Injection (ICSI)
This study looks at an investigational automated, artificial intelligence (AI)-based sperm selection technology called the BAIBYS™ System.
- Trial name
- Benchmark (NCT06990906)
- Testing
- BAIBYS Sperm selection, Intra cytoplasmatic sperm injection, Conventional manual sperm selection
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- BAIBYS Fertility
Infertility
Evaluation of the Impact of Reduced Oxygen Concentration on Embryonic Development
During this study, patients will undergo a routine in vitro fertilization cycle as they would otherwise if not participating in the study.
- Trial name
- LO2 (NCT02919384)
- Testing
- 2% oxygen concentration in the incubator
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Sterility, Postpartum
Effect of Simethicone on Reducing Bowel Interference During Tubal Resection
Tubal ligation is an everyday procedure for permanent female sterilization. It is usually performed after a vaginal delivery. Minilaparotomy is generally performed by doing small incision at infraumbilical area.
- Trial name
- NCT03429621
- Testing
- Simethicone 80 MG
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Infertility, Infertility, Female
Assessment of Ovarian Reserve Tests in Unexplained Infertile Women
IN UNEXPLAINED INFERTILITY IN WOMEN ,OVARY RESERVE IS BORDERLINE IF ASSESSED USING HIGH-SENSITIVE TESTS.
- Trial name
- NCT02127944
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Prostate Cancer, Sexual Dysfunction and Infertility
Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer
RATIONALE: Participating in a therapy program may enhance communication and intimacy between men with prostate cancer and their partners.
- Conditions
- Prostate Cancer, Sexual Dysfunction and Infertility, Sexuality
- Trial name
- NCT01982058
- Testing
- communication intervention, counseling intervention, nutrition intervention
- Where
- 6 sites in United States
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Infertility
Derivation of New Human Embryonic Stem Cell Lines Lines for Clinical Use
Human embryonic stem cells (hESCs) are isolated from the early human embryo and have the capability to proliferate indefinitely in culture and to develop into nearly every cell of the human body.
- Trial name
- NCT00353197
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Oligozoospermia, Asthenozoospermia
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of STSP-0902 in Healthy Subjects
This is a Phase 1a, randomized, double-blind, placebo-controlled, single ascending dose (SAD) study to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of STSP-0902.
- Trial name
- NCT06563713
- Testing
- STSP-0902 injection
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Staidson (Beijing) Biopharmaceuticals Co., Ltd
Infertility
In Vitro Maturation (IVM) of Human Oocytes
The objectives of this study are to evaluate the clinical efficacy of Natural in vitro Fertilization and in vitro maturation.
- Trial name
- IVM (NCT01550861)
- Testing
- in vitro maturation, Polar Body Biopsy with preimplantation genetic screening
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility, Female, Infertility Unexplained
Pro-inflammatory Cytokines and Implantation Process in Women With Primary Idiopathic Infertility
Infertility is a common, worldwide problem. In about 20% of couples, the causative agent of infertility cannot be identified after routine diagnostic tests.
- Conditions
- Infertility, Female, Infertility Unexplained, Inflammatory Response
- Trial name
- NCT05190250
- Testing
- Pipelle biopsy
- Where
- Poland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Educational Video
Fertility Awareness in University Students
Recent evidence showed that undergraduate students have inappropriate knowledge about reproductive health and infertility. The investigators' aim was to assess the effectiveness of a brief intervention (video) in increasing the…
- Trial name
- FAST (NCT02607761)
- Testing
- Video
- Where
- Portugal
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Infertile Patients
Investigating the Relationships Among Illness Cognition, Social Support, Stress, and Emotional Reactions of Infertile Patients
The current study attempted to explore the relationships among stressors (cognitions of illness, socioeconomic status, social support, marital stressor, social stressor, etc), perceived stress level, and emotional reactions…
- Trial name
- HSA-246 (NCT01257256)
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Infertility, Assisted Reproductive Technology
Microbiome and Metabolome Profiles in Couples Undergoing IVF and Reproductive Outcomes
This prospective observational cohort study investigates the role of the microbiome and metabolome in couples undergoing in vitro fertilization.
- Conditions
- Infertility, Assisted Reproductive Technology, Pregnancy Complications, Pregnancy Loss, Early
- Trial name
- Mi IVF (NCT07532629)
- Where
- 3 sites in Sweden
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Male Infertility
Study of Sperm Molecular Factors Implicated in Male Fertility
Sperm analysis following World Health Organization guidelines is unable to explain the molecular causes of male infertility when basic sperm parameters are within a normal range and women do not present gynaecological pathology.
- Trial name
- NCT00481403
- Testing
- Microarray analysis, Microarray
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Infertility, Female, IVF
RCT to Assess the Impact of Microbiome Status in Infertile IVF Patients at Their First IVF/ICSI Cycle
Although the endometrium has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- NCT04686357
- Testing
- EMMA/ALICE
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Infertility, Female
CAPA In-vitro Oocyte Maturation
In vitro oocyte maturation (IVM) is a mild-approach assisted reproductive technology (ART). Because of its simplicity, the more favorable financial implications (reduced cost) for patients, and the lower health risk profile of…
- Trial name
- NCT06984081
- Testing
- CAPA IVM
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Subfertility
Hormonal Stimulation in IUI Treatment: Is Clomifen Combined With Ethinyl Estradiol Better, Worse or Equal to Menopur
What is the best medication for hormonal stimulation in cycles with high intra-uterine insemination: tablets of Clomifen (5 days) followed by tablets of Ethinyl Estradiol (5 days) or daily injections with Human Menopausal…
- Trial name
- NCT01569945
- Testing
- Clomifen, Ethinyl Estradiol, Menotropins
- Where
- Belgium
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Oligospermia
Hyperbaric Oxygen Therapy for Men Suffering From Infertility Due to Oligospermia.
Infertility in a couple is defined as the inability to achieve conception despite one year of frequent, unprotected intercourse. Infertility affects approximately 12% of couples attempting to conceive.
- Trial name
- NCT05842239
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Infertility, Reproductive Issues
Impact of a Predetermined Day 5 ET vs. a Predetermined Day 6 ET on Clinical Pregnancy Rate After ICSI Treatment
The aim of this prospective multicenter study is to investigate the influence of a predetermined embryo transfer on day 6 compared to a predetermined embryo transfer on day 5.
- Trial name
- NCT06447077
- Where
- Germany
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund
Azoospermia
Testicular Evaluation of Azoospermia Using Micro-Ultrasound
The investigation is a small feasibility study to determine whether there are imaging features related to the seminiferous tubules in the testes under microultrasound.
- Trial name
- NCT06941922
- Where
- 2 sites in United States, Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Paul Shin
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