Clinical trials: Infertility/Sterility
Fertility Issues
PLR and NLR as Predictor Factors for Semen Abnormality
The aim of this study was to evaluate the relationship of seminal parameters with the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR), which are inflammatory markers, in men with an abnormal semen…
- Trial name
- NCT06478199
- Testing
- semen analysis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Infertility
Role of Inhibin A as Biomarker for Ovarian Response for IVF Treatment
To evaluate the role of Inhibin A as bio marker for the number of mature oocytes, compared to Estradiol
- Trial name
- NCT03607409
- Where
- United Arab Emirates
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Male Infertility
Treatment of Severe Male Infertility - Predictive Factors (Imaging)
Testes of men with non-obstructive azoospermia (NOA) are imaged using MRI to find potential differences depending on the outcome, ie. sperm recovery in consequent microdissection testicular sperm extraction (MD-TESE).
- Trial name
- TESE-MRI (NCT02931721)
- Testing
- MRI
- Where
- 2 sites in Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Fertility Disorders, Fertility Issues
Menstrual Phase Endometrial Scratch in IUI Cycles
Patients undergoing treatment with intrauterine insemination (IUI) will be randomized to receive an endometrial scratch or sham procedure during the menstrual phase of the treatment cycle.
- Trial name
- NCT04641598
- Testing
- Endometrial Scratch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Infertility
Assessment of the Sexuality of the Infertile Couple
The study hypothesis is that infertile couples experience an impact of their sexuality impacted during the diagnostic process carried out as part of the medically assisted procreation assessment, and also by the announcement of…
- Trial name
- INFEXO (NCT04539392)
- Testing
- Questionnaires on sexuality
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Infertility, Female
Effects of Pentoxifylline and Vitamin E on Pregnancy Rate in Infertile Women Treated by ICSI:
Our findings will provide preliminary clinical evidence to suggest the new experimental treatment approaches, toward female factor infertility treatment with pentoxyfylline.
- Trial name
- NCT03476564
- Testing
- pentoxifylline, Vit E
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Benha University
Female Infertility, NF-κB Ligand
Clinical Relevance of Modifying RANKL Signaling During Folliculogenesis
Female infertility presents a significant societal challenge that will be aggravated in the future due to delayed parenthood. Our translational research suggests that receptor activator of NF-κB ligand (RANKL) is a novel…
- Conditions
- Female Infertility, NF-κB Ligand, RANKL, Osteoporosis
- Trial name
- NCT07546552
- Testing
- Denosumab, PBS
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Male Infertility
Excision Versus Preservation of Spermatic Cord Lipoma Detected During Subinguinal Varicocelectomy
In the current study, the adult infertile patients with clinical varicoceles will be included. the patients will undergo subinguinal varicocelectomy.
- Trial name
- NCT06257459
- Testing
- subinguinal varicocelectomy
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Infertility
Multi-country, Multi-center Cohort Study of Anti-Mullerian Hormone Profile in Asia Pacific Infertile Patients
This study is to detect the infertile couple (women) Anti-Mullerian Hormone (AMH) profile in major subgroups such as Poly Cystic Ovarian Syndrome (PCOS), Endometriosis, etc via age intervals and ethnic difference.
- Trial name
- NCT04203355
- Where
- 11 sites in China, Hong Kong and 9 more
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Uterine Factor Infertility
Transplantation of Uterus for Uterine infertiLIty From Living Donor or Deceased Donor
Patients with absolute Uterine Factor Infertility (AUFI) are infertile due to the absence of a uterus. The absence of a uterus can be either iatrogenic (hysterectomy for gynecological pathology such as cancer or for obstetric…
- Trial name
- TULIPE (NCT05726305)
- Testing
- Live donor uterus transplantation, Deceased donor uterus transplantation
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Infertile Women Undergoing IVF or ICSI
Observational Study to Develop Dosing Chart
To confirm the predictors based on patient specific characteristics and ovarian response and develop dosing chart when Follitrope™ PFS is administered to infertility women patients.
- Trial name
- NCT04227171
- Where
- South Korea
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- LG Chem
Unexplained Infertility
Role of Routine Hysteroscopy in Management of Cases of Unexplained Infertility
The aim of this work is to assess the value of hysteroscopy in unexplained infertility.
- Trial name
- NCT03380364
- Testing
- hystroscope
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Infertility (IVF Patients)
An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera
A clinical trial will determine the effectiveness of using the Opt-IVF decision support tool for each patient's personalized and optimal drug dosage profile in the United States.
- Trial name
- NCT07148999
- Testing
- Opt-IVF, Control
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Urmila DIwekar
Infertility, Female
Topical Analgesia for Pain Relief in Hysterosalpingography
The study will involve giving topical analgesia or placebo and then assessing pain and satisfaction during and after the procedure in order to see wed to the placebo.hether the topical analgesia has helped in decreasing pain…
- Trial name
- HSG (NCT03802032)
- Testing
- Lidocaine Gel, KY jelly
- Where
- Nigeria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University Teaching Hospital
Infertility, IVF
Health of Frozen Transferred Versus Fresh Transferred Children
In order to give strong recommendation on the efficacy and safety of fresh versus frozen embryo transfer, we conduct this study in order to investigate the physical and mental development of children from fresh versus frozen…
- Trial name
- NCT04099784
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Infertility
The Effects of Two Endometrium Preparation Protocols in Frozen-thawed Embryo Transfer in Women With Irregular Cycles
There are two main cycle regimens used for endometrial preparation for frozen embryo transfer (FET) in women with irregular cycles: hormone replacement therapy cycles (HRT) in which the endometrium is artificially prepared by…
- Trial name
- NCT01780610
- Testing
- Letrozole and human chorionic gonadotrophin, estradiol and progesterone
- Where
- China
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Infertility, Female
Effects of Physical Activity and Fitness, Cardiovascular- and Psychosocial Health on Medically Assisted Reproduction
This prospective observational study aims to investigate the association between physical activity and clinical pregnancy rates in women undergoing medically assisted reproduction.
- Trial name
- REPRO-FIT (NCT07321665)
- Testing
- Health, fitness and lifestyle assessment
- Where
- Switzerland
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Infertility
Miniflare Versus Long Protocol in Poor Responders
The study is performed to compare the outcomes of two stimulation protocols, the minidose long protocol versus the microdose flare protocol in poor responders undergoing IVF/ICSI.
- Trial name
- NCT02681536
- Testing
- Triptorelin, Combined oral contraceptive pills, HMG
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Infertility
Endometrial Assessment of Women With Uterine Infection
Unexplained infertility is clinically diagnosed when there are no apparent or clear factors causing infertility on regular infertility assessment tools .
- Trial name
- NCT03824184
- Testing
- manipulation of endometrium
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Male Infertility, Azoospermia
Evaluating the Safety and Clinical Efficacy of the BAIBYS™ System in Intracytoplasmic Sperm Injection (ICSI)
This study looks at an investigational automated, artificial intelligence (AI)-based sperm selection technology called the BAIBYS™ System.
- Trial name
- Benchmark (NCT06990906)
- Testing
- BAIBYS Sperm selection, Intra cytoplasmatic sperm injection, Conventional manual sperm selection
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- BAIBYS Fertility
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