Clinical trials: Infertility/Sterility
Infertility
Prevalence of Uterine Malformations in Newly Married Unselected Population
Uterine malformation is occur due to the abnormal development of Mullerian canal during embryogenesis and it is known that it reduces the fertility and live birth rate and also increases the abortion and preterm birth rate.
- Trial name
- NCT04686227
- Testing
- 3D Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Ovarian Cancer, Borderline Ovarian Tumors
Treg, Th17 Cells, NKT in Epithelial Ovarian Tumor
The aim of the study was to estimate the percentage and of Treg, Th17 and NKT in peripheral blood and the tissue of the epithelial ovarian tumor and relationship with blood serum level of HE4, CA125, as well as algorithm ROMA.
- Conditions
- Ovarian Cancer, Borderline Ovarian Tumors, Benign Ovarian Tumor, Unexplained Infertility
- Trial name
- NCT03779399
- Testing
- Assessment of percentage of Treg, Th17, NKT and serum level of HE4, CA125 and ROMA.
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Infertility, Assisted Reproductive Technology
Prognostic Value of Progesterone on Oocyte Retrieval Day for In Vitro Fertilization Outcome
This observational study aims the potential role of serum progesterone levels on the day of oocyte pick-up on the probability of pregnancy, in patients undergoing antagonist IVF cycles.
- Trial name
- NCT02109900
- Testing
- Serum Progesterone Levels
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Infertility, IVF
Quality of Human Embryos in IVF, Culturing in Differentiated Oxygen
The goal of this clinical trial is to evaluate the importance of differential O2 tension to the developing embryos. As a secondary aim, we investigate the levels of reactive oxygen species (ROS) in spent media from the developing…
- Conditions
- Infertility, IVF, Embryo
- Trial name
- NCT05737381
- Testing
- Differential oxygen tension
- Where
- Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Oligospermia, Teratospermia
Ramipril for the Treatment of Oligospermia
This is a randomized controlled trial to evaluate the effect of ramipril in stimulating and promoting sperm production in men with low sperm count.
- Conditions
- Oligospermia, Teratospermia, Asthenozoospermia, Male Infertility
- Trial name
- NCT01856361
- Testing
- Ramipril
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility
PC Protocol: Preconceptional Screening
Background: Despite considerable progress in the field of assisted reproductive technology (ART) maximum pregnancy rates generally do not exceed 30%.
- Trial name
- PC (NCT02309073)
- Where
- Netherlands
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Infertility
The Impact of Distress on the IVF Outcome
Stress is a primary reason why in vitro fertilization (IVF) patients drop out of treatment, and it may have a detrimental impact on pregnancy rates, yet there is minimal published research on the efficacy of structured…
- Trial name
- NCT01103973
- Testing
- Mind/Body Program, Control
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Sterility
Effectiveness of Nasal Endoscope Sterilization Using a Novel Rig-S™ Device
This study compares the sterility of rigid nasoendoscopies after being sterilized with a conventional autoclave machine and a novel rig-S device that uses standard high level disinfectant
- Trial name
- NCT04605003
- Testing
- Novel rig-S, Conventional Autoclave machine
- Where
- Malaysia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
CHLAMYDIA INFECTIONS
Immunopathogenesis of Chlamydia
Sexually transmitted Chlamydia trachomatis infections are a widespread public health concern due to their prevalence and potentially devastating reproductive consequences, including pelvic inflammatory disease, infertility, and…
- Trial name
- NCT00607659
- Testing
- No intervention, only observational
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Association Model; Chinese Medicine Physique Types; Health Care Base on Traditional Chinese Medicine; Women Infertility
Discussion on the Association Model of Traditional Chinese Medi-cine Body Constitution and Female Infertility
Abstract Background: Infertility may cause physiological and psychological distress. The Health Promotion Administration in Taiwan has listed infertility improvement under the "Reproductive health and prevention section" in the…
- Trial name
- NCT05725629
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Female Infertility
The Embryologist's Impact on Blastocyst Vitrification and Thawing
The goal of this monocentric retrospective observational study is to analyse, for the first time in literature, the role of the embryologist who freezes and thaws the embryos.
- Trial name
- NCT06220227
- Testing
- vitrification and thawing procedures
- Where
- Italy
- Volunteers
- 6,800 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Infertility
Ovarian Stimulation: Inositol and Melatonin
An efficient protocol of ovarian stimulation is a key part of assisted reproductive technology. In order to obtain the highest oocyte retrieval with no adverse effects, numerous studies have evaluated the efficiency of the…
- Trial name
- NCT01267604
- Testing
- Recombinant FSH (rFSH), rFSH + Inositol + Melatonin
- Where
- 2 sites in Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Infertility, Female
Characterizing Follicles From Auto-transplanted Ovarian Tissue
The aim of the project is to characterize the hormonal conditions in egg follicles in women who, prior to fertility treatment, have had autotransplanted frozen ovarian tissue for the purpose of fertility preservation.
- Trial name
- NCT04905771
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Infertility
Histomorphometry Analysis in Fertile and Infertile Patients
To detect similarities and differences in the endometrium of fertile and infertile patients
- Trial name
- NCT01623063
- Testing
- Hysteroscopy
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Infertility
Endometrial Biopsy in Infertile Patients
When a woman becomes pregnant, the fertilized egg attaches itself to the lining of the uterus (endometrium). The endometrium is constantly changing throughout a woman's menstrual cycle in response to the female hormones estrogen…
- Trial name
- NCT00064935
- Testing
- Endometrial biopsy
- Where
- 8 sites in United States
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infertility
2D Versus SonoAVC Scanning in High Responders
Accurate follicular monitoring of Controlled Ovarian Stimulation by transvaginal ultrasound is considered important for the success of human in vitro fertilization (IVF).
- Trial name
- NCT03610009
- Testing
- 2D ultrasound, SonoAVC
- Where
- Greece
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eugonia
Infertility
Prospective, Randomized Trial Comparing ICSI to Insemination for Non-Male Factor Patients Undergoing PGT-A
Intracytoplasmic sperm injection (ICSI) is a procedure performed during in vitro fertilization (IVF) in which a single sperm is injected directly into an oocyte.
- Trial name
- NCT05548101
- Testing
- ICSI
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Texas Fertility Center
Ovarian Failure, Ovarian Insufficiency
Ovarian Tissue Allo-transplantation
Premature ovarian failure, also known as primary ovarian insufficiency (POI), or premature menopause, affects 1-2% of women under 40.
- Conditions
- Ovarian Failure, Ovarian Insufficiency, Menopause Ovarian Failure, Menopause, Premature
- Trial name
- NCT06673004
- Testing
- Ovarian tissue allo-transplantation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Male Infertility
Effect of Eurycoma Longifolia (DLBS5055) and Multivitamins (Vitamin C+Vitamin E+ β-carotene) for Infertile Males
Infertility is defined as the inability of a couple to get pregnant after one year of regular and unprotected sexual intercourse.
- Trial name
- NCT06100432
- Testing
- DLBS5055 200mg, Multivitamin (Vitamin C 500mg + Vitamin E 100IU + Beta Carotene 10000IU)
- Where
- Indonesia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Duta Wacana Christian University
Infertility
Study of Gene Associations and Infertility
The purpose of this this study is to use DNA screening strategies to identify genes and localize genomic regions that are differentially expressed in patients with infertility to further understand the genetic basis for…
- Trial name
- NCT01223092
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
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