Clinical trials: Infertility/Sterility
Male Infertility
Effect of Liver Cirrhosis on Semen Parameters and Reproductive Hormones
Normal testicular hormonal and spermatogenic function depends not only on the testis itself, but also on the integrity of the hypothalamus and anterior pituitary.
- Trial name
- NCT03167749
- Testing
- Laboratory test
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility
The Impact of Lifestyle Behaviors on In Vitro Fertilization (IVF) Outcome
Many women undergoing in vitro fertilization (IVF) ask their doctor if there are any behaviors they should avoid, or any behaviors they should emphasize during their IVF cycle.
- Trial name
- NCT01119391
- Testing
- There was no intervention; this was a survey only study
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility
Mitochondrial Activity of Cumulus Cells From the Cumulus-oocyte Complex and Oocyte Competence
The need for non-invasive biomarkers of oocyte competency has become urgent as women increasingly delay attempts at childbearing.
- Trial name
- NCT02793752
- Testing
- Age
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
Female Infertility
Effect of Growth Hormone on Uterine Receptivity in Women With RIF in an Oocyte Donation Program
105 infertile women are enrolled in the randomized controlled trial: 70 women with a history of RIF with donated oocytes and 35 infertile women undergoing the first oocyte donation attempt.
- Trial name
- NCT03237117
- Testing
- Growth Hormone (GH)
- Where
- Spain
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Competence Centre on Health Technologies
Insulin Resistance, Oligospermia
Insulin Resistance in Idiopathic Oligospermia and Azoospermia
Insulin resistance in men can be the underlying major factor in reproductive abnormalities ( chronic hypospermatogenesis ) as well as metabolic abnormalities similar to polycystic ovarian syndrome ( PCOS ) in women.
- Conditions
- Insulin Resistance, Oligospermia, Azoospermia
- Trial name
- NCT01509482
- Testing
- blood samples
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Egyptian IVF-ET Center
Ovarian Stimulation
Mechanical Stimulation of the Ovary for Infertility Treatment in Patients With Very Low Ovarian Reserve
Examine the possibility that mechanical stimulation and ovarian fragmentation in women with premature ovarian failure or low ovarian reserve intended for egg donation may cause early follicular recruitment and increase chances of…
- Trial name
- NCT03298750
- Testing
- Resection of ovarian tissue and mechanical stimulation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Endometriosis
Open Label Immunotherapy of Endometriosis
Endometriosis is a chronic gynecological disease characterized by sustained painful symptoms that are responsible for a decline in the quality of life of sufferers.
- Trial name
- NCT03340324
- Testing
- V-Endo
- Where
- Mongolia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Immunitor LLC
Infertility
Comparison of the Long GnRH Agonist Protocol and the Flexible GnRH Antagonist Protocol of Ovarian Stimulation
The purpose of this study is to compare the efficacy of two controlled ovarian stimulation protocols, the GnRH agonist protocol, widely known as the "long" protocol, and the flexible GnRH antagonist protocol, in terms of…
- Trial name
- NCT00417183
- Testing
- Arvekap 0.1 mg (Triptorelin, Ipsen, France), Ganirelix 0.25 (Orgalutran, Organon, The Netherlands)
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Eugonia
Infertility
Comparison Between Recombinant Versus Urinary hCG for Ovulation Induction in High Responders
The purpose of this study is to compare the clinical outcomes of recombinant human chorionic gonadotrophin (rHCG) and urinary HCG (uHCG) in patients undergoing IVF cycles.
- Trial name
- NCT00415766
- Testing
- rHCG 250ug, uHCG 5000 IU, uHCG 7500 IU
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eugonia
Infertility
Corifollitropin Alfa Versus Recombinant Follicle Stimulating Hormone (FSH) in Ovarian Stimulation of Women Undergoing in Vitro Fertilisation
The use of corifollitropin alfa is superior in terms of pregnancy outcome parameters as compared to recombinant follicle stimulating hormone (FSH) during ovarian stimulation protocols in women undergoing in vitro fertilisation.
- Trial name
- NCT01319695
- Testing
- corifollitropin alfa, recombinant follicle stimulating hormone (FSH)
- Where
- 2 sites in Greece
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Infertility
Elonva in Combination With Hp-FSH Versus Elonva With Low Dose hCG
The study compares in a randomized controlled way two stimulation methods. One of these stimulation methods implements a new insight in ovarian follicular growth.
- Trial name
- NCT03208972
- Testing
- low dose hCG, hp-FSH, Corifollitropin Alfa
- Where
- Belgium
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- AZ Jan Palfijn Gent
Ultrasound, Sterile Puncture Area
Ultrasound-guided Blood Sampling With a Sterile and Dry Puncture Area
Thousands of vein punctures are done every day at hospitals worldwide. Vein puncture are performed in connection with blood sampling, peripheral intravenous catheter (PIV) placement or blood donation.
- Conditions
- Ultrasound, Sterile Puncture Area, Blood Sampling
- Trial name
- NCT01785225
- Testing
- A product type of the modified commercial drape Tegaderm (R)
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Infertility
Effect of Psychological Intervention on Drop-out Rates in IVF
The most common reason why insured In Vitro Fertilization (IVF) patients drop out of treatment is the distress caused by the treatment.
- Trial name
- NCT01318291
- Testing
- CCRI Group, Control
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Obesity, Childhood, Lifestyle Intervention
Obesity-fertility Cohort Study: Protocol for the Assessment of Children Aged 6-12 Years and Their Mothers
Maternal preconception obesity and adverse gestational metabolic health increase the risk of childhood obesity in offspring. A group of investigators from Université de Sherbrooke therefore developed a lifestyle intervention…
- Conditions
- Obesity, Childhood, Lifestyle Intervention, Preconception Care
- Trial name
- NCT06402825
- Testing
- Fit-for-Fertility program
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Infertility, Female, Web
Responsive Web-based Roadmap (InT-mAp) in Infertility Treatment
Infertility affects approximately 48 million couples and 186 million individuals globally, and it has biological, psychosocial, and economic problems in couples.
- Conditions
- Infertility, Female, Web, Anxiety, IVF
- Trial name
- InT-mAp (NCT05890625)
- Testing
- On going treatment, InT-mAp
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Endometriosis
ENDOMET - Novel Diagnostic Tools and Treatments for Endometriosis
Endometriosis is a chronic disease characterized by the presence of functional endometrial glands and stroma in ectopic locations outside the uterine cavity.
- Trial name
- ENDOMET (NCT01301885)
- Testing
- Laparoscopy/laparotomy
- Where
- 4 sites in Finland
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Infertility
A Comparative Analysis of Arterial Blood Flow in Unexplained Infertility, Tubal Infertility and Fertile Groups
Factors affecting the success of the treatment of infertility can evaluate before and after embryo transfer in two stages. Most of the patients reach the embryo transfer stage.
- Trial name
- NCT02393235
- Testing
- doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Suleymaniye Birth And Women's Health Education And Research Hospital
Infertility
An Open-label, Single Center Trial to Assess the Pharmacokinetics, Pharmacodynamics and Safety of Org 36286 (P07004)
The objectives of this study were to study the pharmacokinetics, pharmacodynamics and safety of Org 36286 after a single subcutaneous administration in healthy females.
- Trial name
- NCT00647933
- Testing
- Org 36286, Lyndiol®
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Infertility, Premature Ovarian Failure
Flexible GnRH Antagonist vs Flare up GnRH Agonist Protocol in Poor Responders
The purpose of this study is to compare ovulation induction using a flexible GnRH antagonist protocol and flare up GnRH agonist protocol in IVF patients with poor response to ovarian stimulation.
- Trial name
- NCT00417066
- Testing
- Ganirelix 0.25mg (Orgalutran, Organon, The Netherlands), Arvekap 0.1mg (Triptorelin, Ipsen, France)
- Where
- Greece
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Eugonia
Anxiety, Depression
Risk Factors of Psychiatric Disorders and Sexual Dysfunction in Infertile Men
To investigate the prevalence of psychological symptoms and sexual dysfunction, and to estimate their possible interactions in infertile men.
- Conditions
- Anxiety, Depression, Sexual Dysfunction, Infertility
- Trial name
- NCT01893216
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
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