Clinical trials: Infertility/Sterility
Metabolic Syndrome X, Infertility
Female Subfertility: a Metabolic and Vascular Profile
Introduction: Overall, 10 - 15% of couples seek specialist help once in their lives when a spontaneous pregnancy does not occur.
- Trial name
- NCT02136472
- Where
- Netherlands
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Infertility
A Clinical Trial to Evaluate the Efficacy and Safety of DR-2011 for In Vitro Fertilization
This is a multi-center study to evaluate the effects of DR-2011 compared to a progesterone gel in women undergoing in vitro fertilization with fresh eggs.
- Trial name
- NCT00615251
- Testing
- DR-2011, Crinone 8%
- Where
- 29 sites in United States
- Volunteers
- 1,297 people, healthy volunteers welcome
- Sponsor
- Duramed Research
Resolve Infertility
Acceptance of Uterus Transplantation
Transplantation of an uterus
- Trial name
- NCT03048396
- Testing
- Uterus transplantation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Infertility, Female, Infertility
Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI
Female inability to conceive a child. The purpose of this prospective randomized, double-blinded, double dummy, two-arm cross-over study is to investigate the difference on histological, transcriptional and immunological level in…
- Conditions
- Infertility, Female, Infertility, Genital Diseases, Male, Genital Diseases, Female
- Trial name
- NCT03677336
- Testing
- Dydrogesterone Oral Tablet, Micronized progesterone
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Erectile Dysfunction, Azoospermia
Trial to Evaluate Erectile Function, Fertility and Sperm Count in Male Cyclists Compared to Age Matched Controls
Bicycle riding is associated with related diverse urogenital symptoms ranging from genital numbness to erectile dysfunction (ED).
- Trial name
- NCT00282477
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Sexual Dysfunction, PCOS
Sexual Dysfunction in Infertile Women With PCOS Undergoing Fertility Treatment
Infertility, defined as the inability to become pregnant after one year of regular unprotected sexual intercourse. It is estimated that around 20 % of couples suffer from infertility with prevalence rates of infertility differing…
- Trial name
- NCT05402800
- Testing
- FSFI questionnaire
- Where
- Egypt
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hyperprolactinemia, Subfertility
Hyperprolactinaemia Management in Reproductive Services at University Hospital of Coventry and Warwickshire
Hyperprolactinaemia and thyroid disorders can significantly reduce fertility by causing ovulatory dysfunction. There is no evidence to suggest treatment of hyperprolactinaemia in the presence of regular ovulatory menstruation…
- Conditions
- Hyperprolactinemia, Subfertility, Subclinical hypothyroïdism
- Trial name
- NCT03569787
- Testing
- MRI Pituitary
- Where
- United Kingdom
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Infertility
Evaluation of the Alife Hera System as an Adjunctive Tool for the Prioritization of Embryos Deemed Suitable for Transfer
To evaluate the clinical pregnancy rate (pregnancy defined as fetal heartbeat at 6-8 weeks) with the adjunctive use of the Hera System (Hera System used with traditional morphological grading) with embryos already deemed suitable…
- Trial name
- LOTUS (NCT05483985)
- Testing
- Hera Score
- Where
- 7 sites in United States
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Alife Health
Nursing Education, Clinical Skills Training
"EFFECTS OF PEYTON'S MODEL"
Detailed Description This randomized controlled trial aims to compare the effectiveness of three educational approaches in improving nursing students' knowledge, clinical skill performance, and self-efficacy regarding sterile…
- Trial name
- MU-NS-PEYTON26 (NCT07732049)
- Testing
- Peyton Four-Step Teaching Model, Traditional Demonstration-Based Teaching
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Infertility (IVF Patients), Infertility Assisted Reproductive Technology
Quantifying Uterine Elastography in Menstruating Women
This study is aiming to characterize the elasticity of the female reproductive tract including the uterus, cervix and ovary using shear wave elastography at different times during the menstrual cycle and define the standard…
- Trial name
- QUEST (NCT06816381)
- Testing
- Shear wave elastography measurements
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Poor Response to Ovulation Induction, PCOS
The Angiotensin-Melatonin Axis in Poor and Hyper Responders for IVF Treatment
According the World Health Organization (WHO), infertility is a disease of the male or female reproductive system defined by the failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse.
- Conditions
- Poor Response to Ovulation Induction, PCOS, Endometriosis, Infertility, Female
- Trial name
- NCT05298657
- Where
- United Arab Emirates
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fatima College of Health Sciences
Cervical Mucus Dysfunction, Infertility, Female
Identification of Biomarkers in Cervical Mucus
Cervical mucus is a biological fluid secreted by the endocervical glandular epithelium whose quantitative and qualitative characteristics vary in response to the hormonal stimulus produced by the ovary during the woman's…
- Trial name
- IBISCUS (NCT06771401)
- Testing
- cervical mucus sampling
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Premature Ovarian Failure
Dehydroepiandrosterone (DHEA) Treatment and Premature Ovarian Failure (POF)
The experimental focus of this project is on the interaction of DHEA treatment on pregnancy in women with open tubes, fertile male partners and evidence of premature ovarian failure.
- Trial name
- DHEAFert2 (NCT00948857)
- Testing
- Dehydroepiandrosterone
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- David H. Barad
Male Infertility, Testicular Diseases
Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm
Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility.
- Conditions
- Male Infertility, Testicular Diseases, Urologic and Male Genital Diseases, Lead Poisoning
- Trial name
- NCT00012480
- Where
- 3 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Infertility
Assessment of the Sexuality of the Infertile Couple
The study hypothesis is that infertile couples experience an impact of their sexuality impacted during the diagnostic process carried out as part of the medically assisted procreation assessment, and also by the announcement of…
- Trial name
- INFEXO (NCT04539392)
- Testing
- Questionnaires on sexuality
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Infertility
Novel Approach for Embryo Transfer Medium by Adding Cytokine to Hyaluronan Enriched Embryo Transfer Medium (Embryo Glue)
It was proven that the Cytokine granulocyte-Macrophage clony stimulating factor had been found naturally in reproductive tract so our target is to test its effect if added to embryo transfer medium.
- Trial name
- NCT02422134
- Testing
- Cytokine group
- Where
- 2 sites in Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ibn Sina Hospital
Infertility, Female
PROspective Study of Mothers' and Infants' Social and Epidemiologic Determinants of Health
The goal of the PROMISE study is to determine how pre-conception lifestyle factors (e.g., sleep, nutrition, physical activity) affect short- and long-term reproductive outcomes.
- Trial name
- PROMISE (NCT05358483)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Maternal Cardiometabolic Health, Infertility
St Mary's Assisted Reproductive Technology and Cardiometabolic Health: Modifiable Targets for Multimorbidity Prevention (START-HEALThY)
The main causes of death in women are conditions affecting the heart and blood vessels (cardiovascular disease, CVD). Women who have difficulties getting pregnant (infertility) may be at increased risk, but the reasons for this…
- Conditions
- Maternal Cardiometabolic Health, Infertility, Assisted Reproductive Technology, Cardiovascular Health
- Trial name
- START-HEALThY (NCT07173569)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Infertility (IVF Patients)
The Role of hCG in Thawed Embryo Transfer
This prospective randomized trial will assess the relevance, if any, of a corpus luteum induced by hCG in transfers of thawed embryos.
- Trial name
- NCT07004192
- Testing
- HCG injection, No intervention
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Infertility, Female
A Study of HS-10518 in Healthy Adult Premenopausal Females in China
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HS-10518 in healthy adult premenopausal females in China
- Trial name
- NCT07264192
- Testing
- HS-10518
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
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