Clinical trials: Infertility/Sterility
Infertility, Female
Ibuprofen Versus Ketorolac for Pain Relief During Hysterosalpingogram
Hysterosalpingogram (HSG) testing is a vital part of the workup for infertility patients. It is often noted to be biggest pain that patients undergo during the workup.
- Trial name
- NCT05190341
- Testing
- Ibuprofen 800 mg oral, Ketorolac 30mg oral
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Total Shoulder Arthroplasty, Shoulder Infection
Surgiphor Us in TSA
Bacteria is occasionally present in the shoulder during shoulder arthroplasty surgery and is hypothesized to increase the risk of failure of the prosthesis.
- Conditions
- Total Shoulder Arthroplasty, Shoulder Infection, Povidone Iodine
- Trial name
- NCT06601803
- Testing
- sterile saline solution, Surgiphor, Sample Collection
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Infertility
Conventional Infertility Treatment vs. Fast Track to IVF
The purpose of this randomized prospective clinical trial is to determine whether an infertility treatment that moves quickly to In Vitro Fertilization (IVF) is more cost effective than the usual treatment strategy which includes…
- Trial name
- FASTT (NCT00260091)
- Testing
- intrauterine insemination, infertility
- Where
- 7 sites in United States
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infertility, Female
COVID-19 Infection and Reproductive Health in Infertile Women
An increased number of women has been infected by COVID-19 in the last 2 years SARS-CoV-2 infection could have a role in potential disturbances on hormon levels and human fertility Has not completely demonstrated COVID-19 effects…
- Trial name
- COVINF (NCT05435430)
- Testing
- PERSPECTIVE, MULTICENTRIC and observational
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Female Infertility Due to Advanced Maternal Age
Mitochondrial Energy Production in ART (Assisted Reproductive Technology )
Oocyte maturation requires a lot of energy, which is provided by the mitochondria via the synthesis of ATP. The majority of patients with advanced maternal age (AMA) have poor egg quality.
- Trial name
- Mitenergy (NCT02727400)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Infertility, Male
Modern Analyses of the Semen in Evaluating Male Fertility and Treatment Options of Male Infertility
Men are recruited to collect seminal plasma samples and serum samples from men with azoospermia, men receiving medical treatment of infertility and men attending semen analysis.
- Trial name
- SemiFluid (NCT02932865)
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Healthy
An Open Label, Study of the Systemic Exposure to Articaine After Topical Ocular Dosing of AG-920
This is a Phase 1, open-label, non-comparative study in healthy subjects performed in the US. It is designed to assess systemic exposure to articaine and its metabolite articainic acid after dosing a single topical ocular…
- Trial name
- NCT04759339
- Testing
- AG-920
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- American Genomics, LLC
Infertility, Female, First Trimester Spontaneous Abortion
Determination of Circulating Placental Biomarkers Levels to Predict the Pregnancy Outcome of First Trimester After IVF.
This study will assess the predictive potential of circulating placental biomarkers for spontaneous miscarriage within the following month in an IVF setting.
- Trial name
- NCT04387994
- Testing
- Blood samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility Unexplained, Infertility, Male
Impact of DNA Fragmentation in Sperm on Pregnancy Outcome After Intra-uterine Insemination in a Spontaneous Cycle
Infertility affects about 10% of all couples and is defined by a failure to achieve a clinical pregnancy within a year of regular unprotected sexual intercourse.
- Conditions
- Infertility Unexplained, Infertility, Male, DNA Damage
- Trial name
- NCT03319654
- Testing
- DNA fragmentation by TUNEL assay
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Infertility, Male
Abstinence Period and Semen Quality
Does period of abstinence impact progressive motility in oligoasthenoteratozoospermic (OATS) males? In the evaluation of male fertility, semen analysis is an important investigation.
- Trial name
- NCT04955782
- Testing
- samples will be analyzed for semen volume, pH, count, concentration, motility, morphology and viability
- Where
- Oman
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
The Effect of Telehealth Applications on the Level of Anxiety in the Treatment of Infertility
It is expected that 84% natural pregnancy will occur at the end of the first 12 months of sexual intercourse without the use of contraceptive methods.The lack of natural fertility is under the influence of multiple factors.
- Trial name
- NCT05148273
- Testing
- telenursing
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Infertility, IVF
Quality of Human Embryos in IVF, Culturing in Differentiated Oxygen
The goal of this clinical trial is to evaluate the importance of differential O2 tension to the developing embryos. As a secondary aim, we investigate the levels of reactive oxygen species (ROS) in spent media from the developing…
- Conditions
- Infertility, IVF, Embryo
- Trial name
- NCT05737381
- Testing
- Differential oxygen tension
- Where
- Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Erectile Dysfunction, Azoospermia
Trial to Evaluate Erectile Function, Fertility and Sperm Count in Male Cyclists Compared to Age Matched Controls
Bicycle riding is associated with related diverse urogenital symptoms ranging from genital numbness to erectile dysfunction (ED).
- Trial name
- NCT00282477
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Male Infertility
The Impact of Lifestyle on Sperm Telomere Length and Telomerase Activity in Men Undergoing IVF Treatments
This aim of this study is to determine the impact of lifestyle on telomere length and telomerase enzyme activity on sperm cells of men undergoing IVF treatments.
- Trial name
- NCT04158765
- Testing
- DNeasy Tissue Kit (QIAGEN Inc., Mississauga, Ontario, Canada) and PCR- based assay (TRAPeze Telomerase Detection Kit; Millipore, Billerica, MA).
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Female Infertility Due to Nonimplantation of Ovum, Complications Associated With Artificial Fertilization
Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression
The purpose of this study is to assess the non-inferiority of a multidose GnRH antagonist (cetrorelix) regimen to a GnRH agonist (triptorelin) long protocol in young infertile women undergoing ovarian stimulation with Pergoveris…
- Trial name
- Pergoveris (NCT01565265)
- Testing
- Pergoveris in long protocol with GnRH agonist, Pergoveris in GnRH antagonist protocol
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Infertility Due to Nonimplantation
Effect Of Intravenous IntralipidTherapyon Pregnancy Outcome in Women With History of Recurrent Implantation Failure Undergoing Intracytoplasmic Sperm Injection-Embryo Transfer Cycle: A Randomized Controlled Trial
To evaluate the effect ofempiricintralipidinfusion therapy on pregnancy outcomes in patient withunexplained recurrentimplantation failure (RIF) undergoIntracytoplasmic sperm injection (ICSI).
- Trial name
- NCT03374163
- Testing
- intralipid 20%
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Infertility
Association of the Mediterranean Diet With Fertility Outcomes
Infertility affects one of every six couples and one out of ten couples may seek fertility treatment such as ovulation induction and assisted reproductive technologies. With respect to diet, several dietary factors, i.e.
- Trial name
- MedDietIVF (NCT03050944)
- Testing
- Lifestyle behaviour and dietary habits assessment
- Where
- Greece
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Infertility
Effects of Intrauterine Administration of Autologous PBMC Modulated With IFNt on Endometrial Cell Populations
The aim of this clinical trial is to investigate the change in endometrial composition during the window of implantation following intrauterine administration of PBMC immunomodulated with IFNt.
- Trial name
- NCT05775211
- Testing
- Intrauterine administration of PBMC immunomodulated with IFNt
- Where
- Bulgaria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nadezhda Women's Health Hospital
Skin Sterility After Use of Ethyl-chloride Spray.
Skin Sterility After Ethyl-Chloride Spray
The aim of this study is to investigate sterility of ethyl-chloride topical anesthetic spray when used prior to an injection. The hypothesis is that the spray does not change the sterility of the injection site after skin is…
- Trial name
- NCT01292850
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Dentistry of New Jersey
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