Clinical trials: Infertility
Postoperative Pain, Edema
Effects of Sterile Kinesio Tape on Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament reconstruction (ACLR) is a surgical tissue graft replacement of the anterior cruciate ligament, located in the knee, to restore its function after an injury.
- Trial name
- NCT04873921
- Testing
- sterile kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Baskent University
Idiopathic Infertility
Effect of Pentoxifylline and Zinc Co-administration in Patients With Oligoasthenoteratozoospermia
The aim of this study is to investigate the impact of co-administration of Pentoxifylline and Zinc sulfate on oxidative stress, apoptosis, and inflammation, sperm capacitation and parameters in infertile men.
- Trial name
- OAT (NCT05156684)
- Testing
- Pentoxifylline, zinc, zinc + pentoxifylline
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Infertility, Spermatozoa
Ejaculatory Abstinence in IUI Cycles
Intrauterine insemination (IUI) combined with ovarian stimulation, has been an extensively used procedure for the treatment of patients with unexplained infertility.
- Conditions
- Infertility, Spermatozoa, Reproductive Disorder
- Trial name
- NCT04361292
- Testing
- INTRAUTERINE INSEMINATION
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Infertility, Recurrent Implantation Failure
Endometrial Biopsy Protocol for In Vitro Fertilization (IVF)
Endometrial biopsy has been shown to improve IVF pregnancy and live birth rates. The optimal time of performing the biopsy is yet to be established.
- Trial name
- NCT01278706
- Testing
- endometrial biopsy/ies
- Where
- 2 sites in Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Subfertility
RCT on the Effect of Endometrial Injury on Ongoing Pregnancy Rate in Subfertile Women Undergoing IVF
Implantation failure remains one of the major factors limiting success in IVF treatment. It was postulated that the local injury to endometrium induces secretions of cytokines and growth factors such as leukemia inhibitory…
- Trial name
- NCT01977976
- Testing
- Endometrial aspiration by pipelle
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Infertility
Physical Endometrial Manipulation and Its Effect on ICSI
Unexplained infertility is clinically diagnosed when there are no apparent or clear factors causing infertility on regular infertility assessment tools .
- Trial name
- NCT03345251
- Testing
- Hydrotubation
- Where
- Egypt
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Infertility
The Effect of GnRH Agonist Administered in the Luteal Phase on ART Cycle Outcomes
This prospective clinical trial evaluates the effect of a two dose GnRH agonist administered in the luteal phase on the outcome of ART cycles stimulated with the long GnRH agonist and GnRH antagonist protocol.
- Trial name
- NCT02114645
- Testing
- Leuprolide acetate, vaginal progesterone, 4 mg oral estradiol valerate
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Infertility
The Impact of the SPIKES Protocol With IVF Patients
The purpose of this study is to determine if the utilization of the SPIKES protocol for delivering bad news is perceived to be more compassionate and effective than the current standard of care for IVF patients receiving negative…
- Trial name
- NCT04917445
- Testing
- Spikes-focused bad news protocol
- Where
- 2 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility, Female, Perimenopausal Disorder
Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women
Autologous PRP intra ovarian infusion may improve ovarian response and women's hormonal profile and may promote folliculogenesis in perimenopausal women.
- Conditions
- Infertility, Female, Perimenopausal Disorder, Menstrual Cycle Abnormal
- Trial name
- PRP (NCT03951194)
- Testing
- Autologous Platelet Rich Plasma (PRP) intra ovarian infusion
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Embryonic Mosaicism, Embryo Culture Media
Media, Morphokinetics, and Mosaicism
Embryonic aneuploidy is the underlying etiology for the majority of failed implantation and miscarriage. Preimplantation genetic screening (PGS) with transfer of a euploid embryo has been advocated as a strategy for increasing…
- Conditions
- Embryonic Mosaicism, Embryo Culture Media, Embryo Morphokinetics, Infertility
- Trial name
- 3M (NCT03503877)
- Testing
- EmbryoScope Plus, GLOBAL MEDIA, SAGE MEDIA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Female , Infertility
Comparison Between Effect of Enoxaparin and Clopidogrel on Improving Pregnancy Rate in ICSI
Comparison between effect of enoxaparin and clopidogrel on improving pregnancy rate in ICSI
- Trial name
- NCT02696330
- Testing
- clopidogrel, enoxaparin
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Male Infertility, Infertility, Male
The Evaluation of the Effect of Microfluidic Sperm Sorting Chip 'Labs-on-a-chip' on IVF Success in Male Factor
Microfluidic chips are one of the methods of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation in the classical gradient density (Percoll) method used in sperm…
- Trial name
- NCT03960229
- Testing
- MicroFluidic Sperm Sorting Chips, Gradient-Density Centrifugation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility
The Impact of Lifestyle Behavior on in Vitro Fertilization (IVF) Outcome
The purpose of this study is to prospectively examine the impact of various lifestyle habits in both men and women on the outcome of in vitro fertilization.
- Trial name
- NCT01404858
- Testing
- There is no intervention; this is a survey only study
- Where
- United States
- Volunteers
- 12,800 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Embryo Aneuploidies, Implantation Rates
Preimplantation Genetic Screening (PGS) in Advanced Female Age and Male Severe Factor
Preimplantation Genetic Screening (PGS) is used for the selection of chromosomally normal embryos before the transfer in IVF treatments in many cases.
- Conditions
- Embryo Aneuploidies, Implantation Rates, Infertility
- Trial name
- NCT01571076
- Testing
- PGS, Prolonged culture
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Igenomix
Infertility
Optimizing the Temperature for Embryo Culture in In Vitro Fertilization
Many human and animal studies over the past 40 years have revealed that ovaries and Fallopian tubes have a lower temperature than core body temperature, especially around the time of ovulation and early embryo development.
- Trial name
- NCT01506089
- Testing
- 36 degrees Celsius
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility
Effect of Addition of Aromatase Inhibitor to Ovarian Stimulation Therapy in IVF Treatment
This project seeks to determine whether estradiol suppression achieved with adjuvant treatment with an aromatase inhibitor improves end-follicular and midluteal phase parameters during IVF.
- Trial name
- RIOT-A (NCT02946684)
- Testing
- Letrozole
- Where
- 4 sites in Denmark
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Sven O. Skouby
Infertility, Female, Polycystic Ovary Syndrome
Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS)
To offer patients with oligomenorrhoea or amenorrhoea an alternative to frozen embryo transfer in an artificial cycle, endometrial preparation using letrozole may be a valuable option.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, IVF, Ovulation Disorder
- Trial name
- LEFT (NCT04002635)
- Testing
- Letrozole, estradiol valerate
- Volunteers
- healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Infertility, ART
Automation of the In Vitro Fertilization Laboratory
Enrolled patients will undergo an Assisted Reproductive technology (ART) treatment using intracytoplasmic sperm injection (ICSI, the direct injection of a single sperm cell into an oocyte) as the method of insemination.
- Trial name
- NCT06581068
- Testing
- AURA assisted ART treatment
- Where
- 2 sites in Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Conceivable Life Sciences
Infertility
The Effect of Ulipristal Acetate (UPA) on Women Ovarian Reserve
The uterine leiomyoma is the most common female benign disease.UPA seems to be most effective for the medical management of fibroids and could be place as preoperative adjunct to surgery but also as medical therapy to avoid…
- Trial name
- UPA_ovAge (NCT02361892)
- Testing
- ulipristal acetate
- Where
- Italy
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Infertility
Correlation Between Serum Anti-Müllerian Hormone & Müllerian Ducts Anomalies in Infertility
Anti-Müllerian hormone (AMH), also known as Müllerian inhibiting substance, is a dimeric glycoprotein that belongs to the transforming growth factor-beta family.
- Trial name
- NCT02436538
- Testing
- Anti Mullerian hormone level; Mullerian duct anomaly type
- Where
- Egypt
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Ahmed M.Kamel
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