Clinical trials: Infiltration Anesthesia
Anesthesia
Comparison of Articaine Mandibular Infiltration to Lidocaine Inferior Alveolar Nerve Block in Pediatric Patients
This is a prospective, single-blind, parallel-design randomized controlled clinical trial that aims compare the effectiveness of articaine local infiltration to lidocaine inferior alveolar nerve block (IANB) for restorative…
- Trial name
- NCT04865848
- Testing
- Dental local anesthesia
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Local Analgesia Via Infiltration, Caudal Epidural Anesthesia
Perioperative Analgesia Using Ultrasound Guided Erector Spinae Block vs Ultrasound Guided Caudal Block for Pain Control in Children Aged 2-7 Years Undergoing Lower Abdominal Surgery
The goal of this prospective study is to is to evaluate the perioperative pain management of Erector Spinae Block versus Caudal Block using the Face, Legs, Activity, Cry, Conceal ability (FLACC) Pain Scale inn children aged 2 to…
- Conditions
- Local Analgesia Via Infiltration, Caudal Epidural Anesthesia, Caudal Block, Caudal Block for Postoperative Analgesia
- Trial name
- NCT07281235
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block, Caudal Block Anesthesia
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Knee Surgeries, Total Ankle Arthroplasty
Adductor Canal Block With IPACK Versus 4-in-1 Block for Postoperative Analgesia in Knee Surgery
This randomized interventional study compares the analgesic efficacy of Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) versus the 4-in-1 block technique in patients undergoing knee…
- Conditions
- Knee Surgeries, Total Ankle Arthroplasty, Anterior Cruciate Ligament (ACL) Tear, Posterior Cruciate Ligament Tear
- Trial name
- NCT07700797
- Testing
- Adductor canal block with IPACK, 4 in 1 block
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Dental Anxiety, Pain
Comparison of Five Anesthetic Delivery Systems for Palatal Infiltration
This study is a randomized clinical trial evaluating five different anesthetic delivery systems for palatal infiltration in adults undergoing maxillary molar extraction.
- Conditions
- Dental Anxiety, Pain, Dental, Palatal Anesthesia
- Trial name
- PAL-INJECT (NCT07184879)
- Testing
- Conventional Dental Syringe, Spring-Activated Syringe (PCJ, PAROJECT™), Needle-Free Jet Injector (NFI, Comfort-in™)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sercan Küçükkurt
Pain Perception, Local Anesthesia
Pain Perception Comparison of Computerized vs Conventional Injection Methods
This study was conducted to a Comparison of Pain Perception for Nerve Block and Infiltration Injection Using the Conventional Method and Two Computerized Control Systems.
- Trial name
- NCT06129162
- Testing
- Conventional Syringe, STA Single Tooth Anesthesia® System., Star Pen anesthesia device.
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Anesthesia Efficacy
Anesthetic Efficacy of Liposomal Prilocaine in Maxillary Infiltration Anesthesia
This blinded randomized, crossover, three period study aim to evaluate the anesthetic efficacy of liposome-encapsulated 3% prilocaine compared to 3% plain prilocaine and 3% prilocaine with 0,03IU/mL felypressin, after 1.8mL…
- Trial name
- NCT01073371
- Testing
- Prilocaine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Anesthesia, Local, Needle Phobia
Needle-free Dental Anesthesia
Many patients experience pain and anxiety from traditional needle anesthesia and may avoid necessary dental treatments. The needle-free liquid jet injection(NFLJI) could solve these problems.
- Trial name
- NCT04493528
- Testing
- Meso-Jet, 2% lidocaine(xylocaine), Needle,2% lidocaine(xylocaine)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Anesthesia, Local, Infiltration
A Trial Comparing Pain During Local Tumesent Injection In Fingers Using Different Syringe-Needle Combinations
Background: This study aims to obtain the most favorable syringe and needle combination, which causes the least pain during local anesthesia tumescent injection in the simulation of fully awake hand surgery.
- Conditions
- Anesthesia, Local, Infiltration, Injection Site, Pain
- Trial name
- NCT03736915
- Testing
- Injection using 1 cc of NaCl 0.9%, Patient Preference Question, Questionnaires
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Anesthesia, Local
Intraligamental Local Anesthesia Versus Infiltration Technique for Extraction of Grade II Mobility Maxillary Molars
The study aims to assess the use of intraligamental local anesthetic injection compared to buccal infiltration for extraction of maxillary molars suffering grade II mobility in terms of pain control and extraction duration.
- Trial name
- NCT05875350
- Testing
- Intraligamental local anesthetic injection
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Pain, Postoperative
Comparing Analgesic Effects of Wound Infiltration Using Bupivacaine, Tramadol, and Tramadol Plus Bupivacaine
The goal of this study's clinical trial is to compare in post-operative analgesic effectiveness of wound infiltration using bupivacaine, tramadol, and tramadol plus bupivacaine in patients undergoing elective cesarean section…
- Trial name
- NCT06076707
- Testing
- bupivacain-tramadol
- Where
- Ethiopia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Wollo University
Anesthesia
Tumescent Lidocaine Maximum Safe mg/kg Dosage
This pharmacokinetic clinical trial is a dose ranging study of lidocaine in tumescent local anesthesia. The goal is to understand the absorption pharmacokinetic of tumescent lidocaine and to determine an objective (statistical)…
- Trial name
- TLA (NCT00977028)
- Testing
- Tumescent Local Anesthesia (lidocaine, epinephrine), Liposuction
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Klein, Jeffrey A., M.D.
Anxiety, Dental, Behavior
The Effect of Using Camouflaged Dental Syringe
Seeing the dental syringe can be terrifying, especially for young children. Hiding the dental syringe during local anesthesia (LA) administration can sometimes be challenging for the pediatric dentist.
- Trial name
- Camouflage (NCT06116994)
- Testing
- The buccal infiltration anesthesia with a camouflaged dental syringe (Angelus ™), The buccal infiltration anesthesia with a conventional dental syringe
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Painful Irreversible Pulpitis
Effect of Fentanyl on the Rate of Anesthesia
Achievement of a deep and long-durated anesthesia is vital before most endodontic procedures; therefore, the investigators conducted this study to compare the local infiltration effect of epinephrine-containing lidocaine with/…
- Trial name
- NCT01794533
- Testing
- Lidocaine with Epinephrine+ Normal saline, Lidocaine with Epinephrine + fentanyl
- Where
- Iran
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Discomfort
Comparing Pain Levels With or Without Topical Anesthesia During Infiltration Injection in Patients Undergoing Tooth Extraction.
This randomized clinical trial aims to assess whether the application of 5% topical lidocaine before infiltration anesthesia reduces pain in patients undergoing tooth extraction.
- Trial name
- NCT07707557
- Testing
- 2% Lidocaine hydrochloride infiltrate injection, 5% topical Lidocaine hydrochloride preparation
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Abbasi Shaheed Hospital
Vertebral Compression Fracture, Kyphoplasty
Anesthesia for Percutaneous Kyphoplasty
The aim of this study was to compare ESP with conventional local infiltration anesthesia (CLIA) and extrapedicular infiltration anesthesia (EPIA) with respect to analgesic efficacy in patients underwent elective PKP for VCF.
- Trial name
- Kyphoplasty (NCT07091513)
- Testing
- group ESP
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Injection Pain, Local Anesthesia Infiltration
Clinical Trial Comparing Pain Perception in Children Using Two Different Local Anesthesia Tools
The goal of this clinical study is to learn whether the Super Pen (SP) device can reduce pain during local anesthesia (LA) infiltration for primary teeth compared to the conventional syringe (CS) in children aged 6-12 years.
- Conditions
- Injection Pain, Local Anesthesia Infiltration, Pediatric Patient
- Trial name
- NCT07292194
- Testing
- super pen
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Lamis D. Rajab
Pain, Postoperative, Pain, Acute
External Oblique Intercostal Block in Laparoscopic Cholecystectomy
Adequate postoperative pain management is essential for improving patient comfort and recovery after laparoscopic cholecystectomy.
- Conditions
- Pain, Postoperative, Pain, Acute, Opioid Use
- Trial name
- NCT07164664
- Testing
- External Oblique Intercostal Block, Port-Site Infiltration, ıv morphine PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Lumbar Spinal Stenosis, Lumbar Spine Instability
Ultrasound-guided ESP Block vs. Wound Infiltration in Lumbar Surgery: A Comparative Analysis (ESP:Erector Spinae Plane)
This study aimed to compare the efficacy of ultrasound-guided erector spinae plane block (ESPB) with that of wound infiltration (WI) for postoperative analgesia in lumbar spinal surgeries involving instrumentation.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Spine Instability, Lumbar Spine Degeneration
- Trial name
- ESP (NCT06567964)
- Testing
- Erector Spinae Plane Block(ESPB), Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Anesthesia, Local
PDL Anesthesia Versus Local Infiltration
The literature concerning the success and pain scores of PDL injection technique compared with other techniques remains controversial; whereas some studies found no significant difference in pain scores between local infiltration…
- Trial name
- PDL (NCT03173898)
- Testing
- PDL anesthesia versus local infiltration
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Healthy Participants, Tooth Extraction
Application Of Dentapen In Dental Local Infiltration Anesthesia
The goal of this clinical study is to compare patients' self-reported pain and mental stress during infiltration anesthesia between conventional syringe and Dentapen.
- Conditions
- Healthy Participants, Tooth Extraction, Orthodontic Patients
- Trial name
- NCT07431801
- Testing
- computer controlled local anesthesia delivery device (Dentapen), Control
- Where
- Vietnam
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Son Hoang Le