Clinical trials: Inflamed Gums
Gingivitis, Supragingival Plaque
Evaluation of the Efficacy and Safety of a Loop Stretchable Dental Floss
This will be a single-blind, single-center, parallel, randomized controlled clinical trial to evaluate the efficacy and safety of Floss Loops stretchable floss for the control of gingivitis and supragingival plaque removal…
- Trial name
- NCT06515483
- Testing
- Brushing and Flossing of teeth, Brushing Only
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Indiana University
Plaque, Gingivitis
Randomized Trial to Evaluate the Efficacy of Two Different Toothbrushes on Plaque Control
The aim of the present study was to evaluate the efficacy of two different toothbrushes (manual and sonic) on plaque control
- Trial name
- NCT03099551
- Testing
- Group using manual toothbrush Curaprox 5460 Ultra Soft, Group using sonic toothbrush Edel White
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Gingival Pigmentation, Gingivitis
The Association of Blood Haemoglobin and Colour of Gums
AIM: To evaluate the association of the levels of blood haemoglobin to the distribution and severity of gingival melanin pigmentation at 3 different periodontal health status SAMPLE SIZE ESTIMATION Done using GPower v.3.1.9.2…
- Conditions
- Gingival Pigmentation, Gingivitis, Periodontitis, Healthy
- Trial name
- NCT03791957
- Testing
- Blood Haemoglobin
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KLE Society's Institute of Dental Sciences
Plaque Induced Gingivitis, Halitosis
Role of Kefir Mouth Wash in Oral Health Status Amelioration
The present research aims to evaluate the efficiency of kefir mouthwash in enhancing oral health status by employing an in vivo experimental approach.
- Conditions
- Plaque Induced Gingivitis, Halitosis, Oral Disease
- Trial name
- NCT06900881
- Testing
- Kefir Mouth Wash, Chlorhexidine 0,12%Biofresh Mouthwash
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Plaque Control, Gingivitis Infection
Plaque-Disclosing Agent for Plaque Control of Gingivitis Patients.
Why was this study done? Gingivitis is the earliest and most common form of gum disease. It develops when dental plaque, a sticky layer of bacteria, builds up on the teeth.
- Trial name
- NCT07746128
- Testing
- hree-tone plaque-disclosing agent-assisted oral hygiene instruction
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Atlas University
Gingivitis, Oral Health
Frequency of Oral Hygiene
The purpose of this study is to evaluate the frequency of oral hygiene in the maintenance of gingival health in patients with an adequate method of oral hygiene.
- Trial name
- NCT01630837
- Testing
- frequency of oral hygiene
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Gingivitis
Health Impact of L.Reuteri Consumption in Crew Members of a Naval Ship at Sea
This study is designed to evaluate the impact of the regular consumption of probiotic Lactobacillus reuteri-containing lozenges over a period of 42 days on parameters of oral and general health in crew members of a naval ship at…
- Trial name
- NAVLAC16 (NCT02775019)
- Testing
- Lactobacillus reuteri
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Gingivitis, Periodontitis
Circadian Clock Gene Expression in Periodontal Disease
This observational study aims to investigate whether periodontal inflammation is associated with alterations in the expression of circadian clock-related genes and proteins in gingival tissues.
- Trial name
- PERIOCLOCK (NCT07452783)
- Testing
- Gingival Tissue Biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inonu University
Dental Plaque, Gingivitis
Assessing the Effects of Three Oral Care Regimens
Assessing the effects of three oral care regimen on plaque, gingivitis, and tooth whitening: A randomized, person-centric, comparative effectiveness clinical research study by the Practitioners Engaged in Applied Research and…
- Trial name
- NCT02940821
- Testing
- Toothbrushing, Fluoridated Dentifrice (.15% sodium monofluorophosphate), Fluoridated Dentifrice Whitening System (.454% stannous fluoride with 2% hydrogen peroxide)
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Pearl Network
Gingivitis, Diabetes
Mechanical-chemical Gingival Therapy in Diabetics and/or Obese
Diabetes and obesity affect many people in different countries. Similarly, millions of people have some type of gum disease such as gingivitis.
- Conditions
- Gingivitis, Diabetes, Obesity
- Trial name
- MCGTDO (NCT02123563)
- Testing
- Ultrason Essential oils rinse
- Where
- Brazil
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Dental Plaque, Gingivitis
A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
The aim of this study is to assess the ability of a marketed Cetylpyridinium Chloride (CPC) mouthwash alongside a marketed Stannous Fluoride (SnF2) toothpaste in improving gingival health and reducing plaque accumulation…
- Trial name
- NCT06660069
- Testing
- Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste), CPC Mouthwash (Parodontax Active Gum Health Mouthwash), Regular Fluoride Toothpaste (Crest Cavity Protection)
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- HALEON
Plaque, Gingivitis
A Pilot Study to Evaluate a Method for Plaque When Comparing Stannous Fluoride Toothpaste to a Regular Dentifrice
This study will evaluate the sensitivity of an assay and its ability to split a marketed stannous fluoride toothpaste versus a negative control.
- Trial name
- NCT02543060
- Testing
- stannous fluoride toothpaste, cavity protection toothpaste
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingivitis
Silver Diamine Fluoride and Gingivitis in Geriatric Patients
Gingivitis in the geriatric population is one of the growing global public health concerns, thus finding the most effective and non-invasive approach to prevent and treat gingivitis in the geriatric population is essential to…
- Trial name
- NCT03445286
- Testing
- Silver Diamine Fluoride, Normal Saline
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Texas A & M University Baylor College Of Dentistry
Gingivitis, Dental Plaque Accumulation
6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health
The goal of this clinical trial is to evaluate the clinical efficacy of an antimicrobial mouthrinse, with a particular focus on its effect on established plaque and the improvement of gum health.
- Trial name
- NCT07414173
- Testing
- Test Mouthrinse, Control Mouthrinse
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
The Assessment of Clinical Efficacy of Topical Application of 5% Thymoquinone Gel for Gingivitis Patients
Gingival diseases occur commonly in the global population and herbal products for its intervention have limited body of research evidence.
- Trial name
- NCT05497895
- Testing
- 5% thymoquinone (TQ) gel, Only SRP-one stage prophylaxis
- Where
- Saudi Arabia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Periodontal Disease, Gingivitis and Periodontal Diseases
Hippo Signaling Pathway Proteins in Gingival Crevicular Fluid of Individuals With Periodontal Disease
Periodontal disease is a chronic inflammatory condition of the tooth-supporting tissues in which the host inflammatory response drives the destruction of alveolar bone and periodontal attachment.
- Conditions
- Periodontal Disease, Gingivitis and Periodontal Diseases, Biomarker Discovery and Validation, Pathways
- Trial name
- BYHN-GCF-HIPPO (NCT07759466)
- Testing
- ELISA Biomarker Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Inonu University
Tooth Discoloration, Tooth Sensitivity
At-home Bleaching Using Clear Retainers
The aim of this project is to clinically evaluate patient satisfaction, whitening efficacy, tooth sensitivity, and gingival irritation during at-home whitening with 10% carbamide peroxide using an Essix-type retainer or a Vivera…
- Conditions
- Tooth Discoloration, Tooth Sensitivity, Gingivitis, Satisfaction, Patient
- Trial name
- NCT05835453
- Testing
- Whitening
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Periodontitis
Gas6 and Soluble MerTK in Periodontal Diseases
This study aimed to investigate gingival crevicular fluid (GCF) and serum soluble MerTK (sMerTK) and Gas6 levels in periodontal health and disease.
- Trial name
- NCT07535177
- Testing
- gingival crevicular fluid collection
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Acne Vulgaris, Gingivitis and Periodontal Diseases
Retinoic Acid Therapy and Regulation of Salivary and Serum IL-1β, IL-8 and MCP-1 Levels
This prospective cohort study analysed the effects of systemic retinoic acid use on periodontal status, salivary flow rate (SFR), and salivary and serum levels of interleukin (IL)-1β, IL-8 and monocyte chemoattractant protein…
- Conditions
- Acne Vulgaris, Gingivitis and Periodontal Diseases, Saliva Collection, Inflammation Biomarkers
- Trial name
- NCT06879795
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medipol University
Gingivitis Infection
Chlorhexidine (CHX) Mouthwash With or Without an Anti-Discoloration System (ADS) During Experimental Gingivitis
Recently, a chlorhexidine product with an anti-discoloration system (ADS) was launched in the market. A comparative study was done to confirm the effectiveness of 0.2% chlorhexidine with ADS. The study was single-blinded.
- Trial name
- NCT07696364
- Testing
- Experimental gingivitis model
- Where
- Switzerland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Bern