Clinical trials: Inflamed Gums
Gingival Inflammation
Toothbrush Wear and Its Effect on Subgingival Inflammation Using Two Different Brushing Techniques
Toothbrush plaque removal, along with interproximal flossing, helps to maintain the oral cavity free from periodontal diseases and dental caries.
- Trial name
- NCT03158350
- Testing
- Instructed Brushing Method
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tufts University
Dental Caries, Gingivitis
Effect of a 2-week Sugar Stress on Bacterial Profiles in Whole Saliva
Dental caries is a non-communicable biofilm-mediated disease affecting both crown and exposed root surfaces in the primary and permanent dentitions.
- Trial name
- NCT04199897
- Testing
- Succrose rinsing, Probiotic lozenges, xylitol rinsing
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Plasma Cell Gingivitis
Management of Plasma Cell Gingivitis by Two Surgical Techniques
Two surgical protocols for management of Plasma cell Ginigivitis; either by surgical enblock resection of cold laser resection
- Trial name
- PCG (NCT05236322)
- Testing
- soft tissue laser
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Plaque Induced Gingivitis
Clinical Safety and Efficacy Study of Water Flosser in Enhancing Oral Health Among Healthy Adults Having Plaque-induced Gingivitis and Dental Plaque Accumulation
This is a double-blind, randomized, control-arm clinical study to evaluate safety and efficacy of test water flosser in enhancing oral health among healthy adults having plaque-induced gingivitis and dental plaque accumulation.
- Trial name
- NCT07204951
- Testing
- Gurunanda - Water Flosser, No water Flossing
- Where
- India
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Gingivitis, Dental Plaque
Efficacy of Electric 3D Versus Manual Toothbrushes in Patients With Fixed Orthodontic Appliances
This study evaluates if electric toothbrushes with a 3D action (rotation / oscillation and pulsation) are more effective than manual toothbrushes in removing plaque and reducing gingival inflammation in patients under orthodontic…
- Trial name
- NCT02699931
- Testing
- Electric3D, Manual
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Dental Plaque
Efficacy of Plaque Removal of a Novel Brushing Device
The purpose of this research study is to compare how a novel, automated mouthpiece-based toothbrushing device removes dental plaque compared to a manual toothbrush.
- Trial name
- NCT05038293
- Testing
- Automated mouthpiece-based toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Caries, Gingivitis
Effect of Oral Health Education on Oral Health Status, Treatment Needs and Barriers to Care
Jordanian children have very poor oral hygiene parameters, and this is reflected as very high caries prevalence and poor gingival health conditions.
- Trial name
- NCT04317768
- Testing
- Basic oral health education and motivation, Intensive oral health education and motivation
- Where
- Jordan
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pregnancy, Birth Weight
Periodontal Condition in Pregnancy and Low Birth Delivery Incidence
The objective of this study was the evaluation of periodontal condition in pregnant women and the effect of the treatment of periodontal disease upon low birth weight.
- Conditions
- Pregnancy, Birth Weight, Periodontal Diseases
- Trial name
- NCT02613468
- Testing
- collection of periodontal records, pregnancy parameters, Initial Periodontal Therapy
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Gingivitis
Protocol Efficacy of Mouthwashes in Experimental Gingivitis
This research was performed to find out the clinical efficacy and the anti-plaque and anti-gingivitis properties of a new oral health product (mouthwash and oral gel; StellaLife) compared to chlorhexidine.
- Trial name
- NCT07270952
- Testing
- StellaLife, Chlorhexidine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Gingival Inflammation
Comparison Between the Effect of Triclosan Toothpaste and Chlorhexidine Mouthwash on Gingival Health in a Group of Fixed Orthodontic Patients: A Randomized Controlled Clinical Trial
Study Protocol Introduction Title of the research study Comparison Between the effect of Triclosan Toothpaste and chlorhexidine Mouthwash on Gingival Health in Fixed Orthodontic Patients :A randomization controlled clinical…
- Trial name
- NCT07814898
- Testing
- Triclosan 0.3% toothpaste, sodium fluoride 0.24% toothpaste, Chlorhexidine 0.2% mouthwash
- Where
- Yemen
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Gingivitis
A Proof-of-principle Clinical Study Investigating the Efficacy of an Experimental Dentifrice Containing Sodium Bicarbonate and Sodium Hyaluronate on Gingivitis
The aim of this study is to develop a daily use toothpaste containing sodium bicarbonate, sodium hyaluronate and sodium fluoride with the intention of providing improved/ fast gum healing.
- Trial name
- NCT04737538
- Testing
- Experimental Dentrifrice, Positive control dentifrice, Negative control dentifrice
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gingivitis
Propolis Containing Chewing Gum and Gingivitis
Propolis is a natural, non-toxic, sticky substance produced by honeybees that can kill bacteria, fungi, and larvae invading the beehive. It has been used in the treatment of infections and healing of wounds and burns for years.
- Trial name
- NCT06685419
- Testing
- Propolis containing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- naksaka
Dental Plaque, Gingival Bleeding
Comparison Between Interdental Brush and Water Floss on Plaque Accumulation and Gingival Inflammation in Patients Undergoing Fixed Orthodontic Treatment.
The goal of this clinical trial is to test the ability of water flosser to remove plaque and reduce gingival inflammation in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07240428
- Testing
- Interdental brush, Water floss
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Gingival Bleeding, Von Willebrand Diseases
Gingival Bleeding and Von Willebrand Disease Typ 2 and 3
Von Willebrand disease (VWD) is the most common inherent bleeding disorder resulting in prolonged bleeding time. Gingival bleeding is a frequently reported symptom of VWD.
- Trial name
- NCT03078595
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Goethe University
Dental Plaque, Halitosis
Efficacy of Different Toothbrushes and Hygiene Regimen
To evaluate: 1) Evaluate the efficacy of a regimen commercially available versus brush alone on established plaque and gingivitis on adolescents.
- Trial name
- NCT04216069
- Testing
- Total 12 regimen, Toothbrushing alone
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Gingivitis
Efficacy of the Addition of a Power Interdental Device to an Electric Toothbrush on Gingival Health.
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04003298
- Testing
- Electric toothbrush, Control
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Gingivitis
Efficacy of Oil Pulling Therapy on Supragingival Plaque Growth
Oil pulling is a method based on Ayurvedic medicine which aims to obtain local and systemic benefits by swirling oils in the oral cavity for a period of 15 minutes, before spitting it out.12 Although the exact mechanism of action…
- Trial name
- NCT03962777
- Testing
- chlorhexidine, oil pulling
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baskent University
Periodontal Diseases
Clinical and Microbiological Evaluation Of The Efficacy Of Herbal Mouthwashes in Gingivitis
Plaque-induced gingivitis is a clinical condition that appears to cause persistent inflammation in gingiva. It is a preliminary cause to periodontitis but it can be inverted to address the risk of periodontitis development.
- Trial name
- NCT06904742
- Testing
- Tea tree oil, Thyme oil hydrosol, LISTERINE ZERO Alcohol Mouthwash COOL MINT
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Gingivitis
"The Efficacy of Acacia Catechu Mouthrinse as Antiplaque and Antigingivitis Agent in Fixed Orthodontic Appliance Patients.
To study effect of acacia catechu a herbal extract;as antipaque and antigingivitis agent in patients with fixed orthodontic appliances.This study is a double blind randomized controlled trial.
- Trial name
- NCT02154594
- Testing
- Acacia catechu, Chlorhexidine gluconate, Distilled water
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Plaque Induced Gingivitis, Mouth Diseases
Propolis Lozenges Extract and Their Effect on Salivary Biomarkers and on Oral Health Condition in (19_24) Years Old
The goal of this clinical trial is to test the efficiency of using lozenges containing propolis extract over one week to control gingival inflammation and plaque accumulation by measuring the clinical periodontal parameters…
- Conditions
- Plaque Induced Gingivitis, Mouth Diseases, Periodontal Diseases
- Trial name
- NCT06888453
- Testing
- lozenges containing propolis
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University