Clinical trials: Inflamed Gums
Gingivitis and Periodontal Diseases
Evaluation and Correlation of Serum Fetuin-A Levels in Periodontal Health and Disease: A Clinico-biochemical Study
The present clinico-biochemical study was carried out to estimate the levels of Fetuin A and MMP7 in serum of systemically healthy subjects in periodontal health and disease and to evaluate the impact of periodontal…
- Trial name
- NCT04198610
- Testing
- Non surgical periodontal therapy
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Diabete Mellitus, Dyslipidaemia
Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 Years
Overweight and obesity, as well as periodontitis, are common public health problems with increasing prevalence. Both conditions may be linked through shared mechanisms involving chronic low-grade systemic inflammation.
- Conditions
- Diabete Mellitus, Dyslipidaemia, Chronic Kidney Disease, Psychiatric Disorder
- Trial name
- NCT07880717
- Testing
- Periodontal Examination, Questionnaire interview, Anthropometric measurements
- Where
- Thailand
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Reducing Gingivitis, Clinical Effect
Effectiveness of Coconut Oil Pulling and Moringa Mouthwash Versus Chlorhexidine in Reducing Gingivitis in Diabetic Children
Gingivitis is a common and reversible inflammatory condition, mainly caused by dental plaque, and is particularly prevalent among children.
- Trial name
- NCT07826390
- Testing
- Chlorhexidine mouthwash, Moringa olfera mouthwash, coconut oil pulling
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Amira Yehia Zakaria
Plaque Accumulation, Gingival Inflammation
Triphila Mouthwash Effect as Anti-plaque and Anti-gingivitis in Children
The study aim to to assess the antiplaque and antigingivitis efficacy of Triphala mouthwash versus chlorhexidine mouthwash among children.
- Trial name
- NCT07016659
- Testing
- 0.12% Chlorhexidine Mouthwash ( Hexitol ), Triphila mouthwash
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peripheral Giant Cell Granuloma, Gingival Lesions
Lymphocyte Subpopulations in Peripheral Giant Cell Granuloma
Peripheral giant cell granuloma (PGCG) is a non-neoplastic inflammatory lesion of gingival tissues. This study aims to evaluate and compare lymphocyte subpopulations in PGCG tissues and adjacent healthy gingival tissues obtained…
- Conditions
- Peripheral Giant Cell Granuloma, Gingival Lesions, Gingival Enlargement
- Trial name
- NCT07551310
- Testing
- Immunohistochemical Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ataturk University
Gingivitis
The Effects of Periodontal Therapy on Gingival Crevicular Fluid NLRP3,Caspase-1,IL-1β Levels in Children With Gingivitis
This study aims to determine the levels of NLRP3, caspase-1 and IL-1β concentrations in the gingival crevicular fluid of paediatric patients with gingivitis and their changes after periodontal treatment.
- Trial name
- NCT06507280
- Testing
- Periodontal theraphy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Cystic Fibrosis, Periodontitis
Cystic Fibrosis and Periodontal Diseases
The number of CF adults is increasing year after year (61.7% in 2021) confirming that patients are living longer. These data do not leave aside the desire to see CF patients "age well" considering of all the comorbidities linked…
- Conditions
- Cystic Fibrosis, Periodontitis, Gingivitis
- Trial name
- MucoParo (NCT06133335)
- Testing
- Periodontal examination
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Pemphigoid, Benign Mucous Membrane, Gingivitis Hyperplastic
Peridontal and Intestinal Microbiota in Patients With Gingival Scarring Pemphigoid
Patients suffering from Mucous Membrane Pemphigoid with desquamative gingivitis (MMPg) generally present a more degraded periodontal condition compared with controls.
- Trial name
- MICROPC (NCT06291350)
- Testing
- Plaque sampling and stool collection, periodontal examination
- Where
- 3 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gingivitis, Supragingival Plaque
Evaluation of the Efficacy and Safety of a Loop Stretchable Dental Floss
This will be a single-blind, single-center, parallel, randomized controlled clinical trial to evaluate the efficacy and safety of Floss Loops stretchable floss for the control of gingivitis and supragingival plaque removal…
- Trial name
- NCT06515483
- Testing
- Brushing and Flossing of teeth, Brushing Only
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Indiana University
Plaque, Gingivitis
Randomized Trial to Evaluate the Efficacy of Two Different Toothbrushes on Plaque Control
The aim of the present study was to evaluate the efficacy of two different toothbrushes (manual and sonic) on plaque control
- Trial name
- NCT03099551
- Testing
- Group using manual toothbrush Curaprox 5460 Ultra Soft, Group using sonic toothbrush Edel White
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Polycystic Ovary Syndrome, Gingival Inflammation
Impact of PCOS on Periodontal Status of Adolescent and Adult Age Group Women
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women, primarily affecting the reproductive system, with substantial collateral negative health effects on metabolic, psychological, and cardiovascular…
- Trial name
- NCT05113030
- Testing
- PERIODONTAL STATUS OF FEMALE PATIENTS WITH PCOS (NEWLY DIAGNOSED) OF ADOLESCENT AGE GROUP WILL BE ASSESSED, PERIODONTAL STATUS OF FEMALE PATIENTS WITH PCOS (NEWLY DIAGNOSED) OF ADULT AGE GROUP WILL BE ASSESSED
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Pigmentation, Gingivitis
The Association of Blood Haemoglobin and Colour of Gums
AIM: To evaluate the association of the levels of blood haemoglobin to the distribution and severity of gingival melanin pigmentation at 3 different periodontal health status SAMPLE SIZE ESTIMATION Done using GPower v.3.1.9.2…
- Conditions
- Gingival Pigmentation, Gingivitis, Periodontitis, Healthy
- Trial name
- NCT03791957
- Testing
- Blood Haemoglobin
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KLE Society's Institute of Dental Sciences
Plaque Induced Gingivitis, Halitosis
Role of Kefir Mouth Wash in Oral Health Status Amelioration
The present research aims to evaluate the efficiency of kefir mouthwash in enhancing oral health status by employing an in vivo experimental approach.
- Conditions
- Plaque Induced Gingivitis, Halitosis, Oral Disease
- Trial name
- NCT06900881
- Testing
- Kefir Mouth Wash, Chlorhexidine 0,12%Biofresh Mouthwash
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Plaque Control, Gingivitis Infection
Plaque-Disclosing Agent for Plaque Control of Gingivitis Patients.
Why was this study done? Gingivitis is the earliest and most common form of gum disease. It develops when dental plaque, a sticky layer of bacteria, builds up on the teeth.
- Trial name
- NCT07746128
- Testing
- hree-tone plaque-disclosing agent-assisted oral hygiene instruction
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Atlas University
Gingivitis, Oral Health
Frequency of Oral Hygiene
The purpose of this study is to evaluate the frequency of oral hygiene in the maintenance of gingival health in patients with an adequate method of oral hygiene.
- Trial name
- NCT01630837
- Testing
- frequency of oral hygiene
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Gingivitis
Health Impact of L.Reuteri Consumption in Crew Members of a Naval Ship at Sea
This study is designed to evaluate the impact of the regular consumption of probiotic Lactobacillus reuteri-containing lozenges over a period of 42 days on parameters of oral and general health in crew members of a naval ship at…
- Trial name
- NAVLAC16 (NCT02775019)
- Testing
- Lactobacillus reuteri
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Preterm Birth, Low Birthweight Neonate
Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial
The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conducted in Lilongwe, Malawi and enrolled approximately 10,069 pregnant individuals seeking to evaluate the impact…
- Conditions
- Preterm Birth, Low Birthweight Neonate, Periodontitis, Gingivitis
- Trial name
- XaPPP (NCT07424846)
- Testing
- Xylitol Chewing gum, Sorbitol chewing gum
- Where
- Malawi
- Volunteers
- 6,000 people
- Sponsor
- University of Washington
Gingivitis, Periodontitis
Circadian Clock Gene Expression in Periodontal Disease
This observational study aims to investigate whether periodontal inflammation is associated with alterations in the expression of circadian clock-related genes and proteins in gingival tissues.
- Trial name
- PERIOCLOCK (NCT07452783)
- Testing
- Gingival Tissue Biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inonu University
Dental Plaque, Gingivitis
Assessing the Effects of Three Oral Care Regimens
Assessing the effects of three oral care regimen on plaque, gingivitis, and tooth whitening: A randomized, person-centric, comparative effectiveness clinical research study by the Practitioners Engaged in Applied Research and…
- Trial name
- NCT02940821
- Testing
- Toothbrushing, Fluoridated Dentifrice (.15% sodium monofluorophosphate), Fluoridated Dentifrice Whitening System (.454% stannous fluoride with 2% hydrogen peroxide)
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Pearl Network
Gingivitis, Diabetes
Mechanical-chemical Gingival Therapy in Diabetics and/or Obese
Diabetes and obesity affect many people in different countries. Similarly, millions of people have some type of gum disease such as gingivitis.
- Conditions
- Gingivitis, Diabetes, Obesity
- Trial name
- MCGTDO (NCT02123563)
- Testing
- Ultrason Essential oils rinse
- Where
- Brazil
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Taubate