Clinical trials: Inflammation
Hypertension
Heart Inflammation and Mental Stress Study
The aim of the study is to investigate the neural underpinnings of cardiovascular reactivity to mental stress as a function of HIV and hypertensive risk.
- Trial name
- HIMS (NCT03695146)
- Testing
- Paced breathing, Active relaxation
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Miami
Chronic Obstructive Pulmonary Disease
Multiorgan Pathology in Chronic Obstructive Pulmonary Disease (COPD)
There is increasing evidence in the literature that COPD should not be considered as a localised pulmonary disorder but as a systemic disease involving pathology in several extra pulmonary tissues.
- Trial name
- NCT00864994
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Top Institute Pharma
COVID 19
Impact of Cryopreservation Methods on Post-Thaw SARS-CoV-2 in Semen Samples
Cryopreservation of seminal fluid or spermatozoa from epididymary and testicular retrieval represents a crucial tool in managing conditions of permanent or temporary infertility, as well as in cases of secretory and excretory…
- Trial name
- SEM-COV-19 (NCT06703723)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Systemic Inflammatory Response Syndrome
Evaluation of Corticosteroid in Systemic Inflammatory Response Syndrome
Cardiac surgery and cardiopulmonary bypass (CPB) initiate a whole-body systemic inflammatory response (SIRS) characterized by the activation of leukocytes, monocytes, and the complement cascade.
- Trial name
- NCT03876041
- Testing
- solumedrol, Dexamethasone phosphate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gonarthrosis, Serum Albumin Low
PROGNOSTIC ROLE OF SERUM ALBUMIN LEVEL IN RADIOLOGICAL PROGRESSION OF GONARTHROSIS: IS IT A BIOMARKER IN ITSELF? A BIOMARKER ASSOCIATED WITH SYSTEMIC INFLAMMATION?
The aim of our study is to evaluate the prognostic roles of serum albumin level and systemic inflammation-related indices, including and not including serum albumin level, in the radiological progression of gonarthrosis.
- Trial name
- NCT06159751
- Testing
- serum albumin level
- Where
- Turkey (Türkiye)
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Chronic Periodontitis, Aggressive Periodontitis
IL-34 Levels in Various Types of Periodontitis
The objective of this study is to 1) identification of the impact of IL-34 on the pathogenesis of periodontal disease and determine whether any relationship among the existing levels of Gingival crevicular fluid (GCF) Interleukin…
- Trial name
- NCT04223869
- Testing
- non-surgical periodontal treatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Cancer
Acute Immunological Effects of Exercise in Cancer Patients
The aim of the study is to evaluate and compare immune response to a single exercise intervention in cancer patients and healthy age-maged individuals.
- Trial name
- ACTIVE (NCT05656651)
- Testing
- High intensity interval exercise training
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universität Duisburg-Essen
Healthy, Hypercholesterolemia
Health Effects of Consuming Olive Pomace Oil
Healthy and at risk (hypercholesterolemic) subjects consumed during 4 weeks 45 g/d of either olive pomace oil (OPO) or sunflower oil (SO) as the only dietary fat in a randomized, crossover trial.
- Trial name
- ORUJOSALUD-2 (NCT04998695)
- Testing
- Olive pomace oil, Sunflower oil
- Where
- Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Intracranial Aneurysm, Cerebral Aneurysm
PET-imaging of Unruptured Intracranial Aneurysm Inflammation
The main purpose of this study is to determine if PET-imaging can be used to evaluate inflammation level of intracranial aneurysms, thus helping to evaluate the rupture risk of intracranial aneurysm.
- Conditions
- Intracranial Aneurysm, Cerebral Aneurysm, Inflammation
- Trial name
- PET-IA (NCT04715503)
- Testing
- PET imaging, 18F-FDG, PET imaging, 68Ga-DOTANOC
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Pericoronitis
Third Molar Clinical Trials: Pericoronitis Studies
The purpose of this research study is to find out if the infection around 3rd molars and the resulting inflammation around the gum also produces a general systemic inflammation.
- Trial name
- NCT01882270
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Adults
Enteral Nutrition and Immune Proteins Study
Eligible healthy adults who consent to take part in the study will be randomised to receive either a specialised milkshake for all of their normal daily diet (exculsive enteral nutrition, EEN) or the same specialised milkshake…
- Trial name
- ENIP (NCT06828094)
- Testing
- enteral nutrition
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Muscle Damage, Inflammation
Compared Effect of a Fruit Milk Shake With a Protein-Carbohydrate Supplement on Recovery After Resistance Exercise
The aim of this study is to assess the effect of ingesting a commercial carbohydrate and protein dietary supplement in powder form (P-CHO supplement) or a milk shake with skimmed milk, strawberries and banana (MS), after…
- Conditions
- Muscle Damage, Inflammation, Oxidative Stress, Functional Recovery
- Trial name
- NCT01555775
- Testing
- P-CHO supplement, Fruit Milk Shake
- Where
- Portugal
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Arthritis, Rheumatoid, Inflammation
A Study To Look At The Safety Of SB-681323 In Healthy Adult Subjects After Intravenous Administration Of A Single Dose
SB-681323 inhibits the action of an enzyme which is known to contribute to the inflammation seen in such conditions as Chronic Obstructive Pulmonary Disease and Rheumatoid Arthritis.
- Trial name
- NCT00439881
- Testing
- SB-681323
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Neuroinflammation
Test Re-Test Reliability of [11C]PF-06809247 as a Novel PET Tacer
This is a study measuring the binding kinetics and test-retest characteristics of a subpharmacological dose of [11C]PF-06809247 Monoacylglycerol lipase (MAGL) Positron Emission Tomography (PET) tracer in healthy adult subjects.
- Trial name
- NCT03100136
- Testing
- [11C]PF-06809247
- Where
- 3 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Pfizer
Sepsis, Septic Shock
Neutrophil FFA2/GPR43 Receptor Expression in Patients With the Diagnosis of Sepsis
This study seeks to elucidate the quantitative expression of G - protein receptor 43/free fatty acid (GPR43/FFA2) receptors in patients with the diagnosis of sepsis and specifically, its expression as it relates to the severity…
- Conditions
- Sepsis, Septic Shock, Multiple Organ Dysfunction, Intra-abdominal Sepsis
- Trial name
- GPR43Sepsis (NCT02699905)
- Testing
- phlebotomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Obesity, Inflammation
Gene Expression and Inflammation in Overweight Subjects
This study will look at gene expression (whether particular sets of genes are activated ["turned on"] or deactivated ["turned off"]) in overweight people as compared to non-overweight individuals.
- Conditions
- Obesity, Inflammation, Nutrition Therapy
- Trial name
- NCT00344266
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Aging Well
Gut Health, Inflammation, Hormones
Pilot exploratory study on the effect of a Bifidobacterium breve extract, as VMK223, on plasma inflammatory markers, saliva hormones, gut microbiota and tolerance in females over 50years old.
- Trial name
- NCT04267731
- Testing
- VMK223, Cellulose
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vemico Ltd.
Attention-Deficit/Hyperactivity Disorder
Inflammation in Children With Attention-Deficit/Hyperactivity Disorder
The aim of this study is to investigate the inflammatory response in children with this disorder.
- Trial name
- ADHD_CYTO (NCT00391495)
- Testing
- Blood drawing
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
HIV Prevention, Sexually Transmitted Diseases
STI Care Model to Reduce Genital Inflammation and HIV Risk in South African Women
The goal of this prospective cohort study is to determine if a model of care including point-of-care testing, immediate therapy, expedited partner therapy and test of cure will result in a higher cure rate and a lower recurrence…
- Trial name
- NCT03407586
- Testing
- Point-of-care STI testing
- Where
- South Africa
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
Athlete, Sedentary Behavior
Health Parameters in Soccer Players and Sedentary Individuals After Consuming a Synbiotic
The main objective of this research was to carry out an experimental study, triple blind, on the possible immunophysiological effects of a nutritional supplement (Synbiotic, Gasteel Plus®, Heel España S.A.U.), containing a…
- Trial name
- NCT04776772
- Testing
- Synbiotic complement
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Catholic University of Murcia
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