Clinical trials: Inflammation
Periodontitis, Gingivitis
Regulatory T Cell With Related Interleukins in Periodontal Disease Progression
T Regulatory cells which suppressor subset of T cells and related cytokines remain in blood and infiltrates into the tissue under need.
- Trial name
- NCT06135116
- Testing
- Flow Cytometric Detection of Regulatory T Cells and Cytokines analysis by ELISA
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Obesity, Metabolic Syndrome
Lipoproteins and ImmunoMetabolism
Dietary interventions have been consistently proposed as a part of a comprehensive strategy to lower the incidence and severity of atherosclerosis and cardiovascular diseases (CVD).
- Conditions
- Obesity, Metabolic Syndrome, Metabolism Disorder, Inflammation
- Trial name
- NCT05746013
- Testing
- Lipid Emulsion
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Seville
Bipolar Disorder, Schizophrenia
Immuno-Genetic, Inflammation, Retro-Virus, Environment
Immunology combined to neurobiology now offer prominent tools to yield biomarkers, so far missing in psychiatry, and to design innovative treatment approaches based on the discovery of new molecular and cellular targets.
- Trial name
- I-Give (NCT02878408)
- Testing
- Blood sampling
- Where
- 6 sites in France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Pr. Marion Leboyer
Vitamin D on Tumor Response and Inflammatory Markers, Colo-rectal Cancer
Evaluation the of Role of Vitamin D Supplement on Tumor Response, Inflammation and Apoptosis in Patients With Stage II or III Colorectal Cancer Receiving Chemotherapy.
The aim of this work is to assess the of role of Vitamin D supplement on tumor response, inflammation and apoptosis in patients with stage II or III colorectal cancer receiving chemotherapy using BAX protein and Tumor necrosis…
- Trial name
- NCT07241247
- Testing
- Vitamin D
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tanta University
Sepsis
Pro-adrenomedullin as a Prognostic Marker in Neonatal Sepsis
The aim of this study was to clarify the prognostic value of serum pro-Adrenomedullin level in neonatal sepsis. Eighty term and preterm neonates with sepsis were enrolled in this study.
- Trial name
- NCT01362504
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Food Allergy, Food Hypersensitivity
Mucosal IgE to Improve Diagnosis of Food Allergy and Food Hypersensitivity
Aim of the study is to improve the diagnosis of food allergy and hypersensitivity. Intestinal homogenates will be used to determine total IgE, specific IgE, tryptase, histamine and inflammation parameters (IFNgamma, TNFalpha).
- Trial name
- NCT05259826
- Testing
- biopsy sampling
- Where
- Germany
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Inflammation, Gastrointestinal Symptoms
Evaluating the Ability of a Multi-Strain Postbiotic to Impact Inflammation, Immune Components, Gastrointestinal Symptoms, Recovery, Anxiety, and Intestinal Permeability
This study will evaluate the effects of a multi-strain postbiotic supplement on markers of inflammation, immune function, gastrointestinal symptoms, psychological well-being, and intestinal permeability in healthy adults.
- Trial name
- BIO (NCT07387991)
- Testing
- Multi-Strain Postbiotic
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Acute Kidney Failure With or Without:, MODS
Citrate Pharmacokinetics and Regional Citrate Anticoagulation in CRRT
1. To compare the differences of citrate pharmacokinetics in healthy individuals and critically ill patients as well as the influential factors. 2. To validate a pharmacokinetic model which has been established in a formal paper.
- Conditions
- Acute Kidney Failure With or Without:, MODS, Sepsis, Hepatic Insufficiency
- Trial name
- NCT00948558
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Sepsis
PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors
The purpose of this study is to define the natural history and causes of chronic critical illness (CCI) in surgical intensive care patients who have had sepsis.
- Trial name
- PICS (NCT02276417)
- Testing
- Blood collection, Urine collection, Bioimpedance Analysis
- Where
- United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- University of Florida
Antioxidant Status, Inflammation
Effect of Consuming Pork From Seaweed Extract Fed Animals on Antioxidant Status
Red meat makes a significant contribution to the human diet. The most widely consumed meat globally is pork which accounts for 36% of overall meat intake with beef and poultry contributing 22% and 35%, respectively.
- Trial name
- NCT02682017
- Testing
- Pork meat from pigs feed with a standard feed., Pork meat from pigs fed a feed with a Laminarin/fucoidan mix
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Behavioral Resilience, Biological Resilience
Cognitively-Based Compassion Training and Mindfulness Attention Training Program
This project will explore the effect of Cognitively-Based Compassion Training or mindfulness training on behavior and saliva stress hormones in elementary school-age children.
- Trial name
- NCT01592188
- Testing
- Cognitively-Based Compassion Training (CBCT), Mindfulness training
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Emory University
Myelodysplastic Syndromes
Sterile Inflammation and Molecular Aberrations in MDS
The objective of this study is the description of the possible association between genetic mutation/aberration profiles, inflammatory tonus and clinical phenotype based on PROMs and HRQoL.
- Trial name
- InflamGen (NCT04313231)
- Testing
- Next Generation Sequencing, Tumorimmunological examinations - multiplex assays/quantitative polymerase chain reaction, flow cytometry
- Where
- Austria
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Inflammatory Response, Muscular Injury
Mangoes and Exercise Inflammation
Vigorous exercise bouts result in significant inflammation and muscle soreness. Our research group has published several papers showing that ingestion of various types of fruits enhances inflammation resolution after exercise.
- Trial name
- NCT05409105
- Testing
- Mangoes, Water
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Inflammation
Inflammation and Daily Life Study
UCLA researchers looking for healthy individuals (age 45-60) to participate in a study investigating whether an anti-inflammatory medication can impact daily life experiences.
- Trial name
- NCT03771612
- Testing
- Naproxen
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Type 2 Diabetes
Role of Interleukin-1 in the Regulation of Muscle Derived Interleukin-6 During Exercise
Aim: Evaluate the regulation of muscle derived Interleukin-6 (IL-6)during exercise and in particular whether it is regulated by the Interleukin-1 (IL-1) system.
- Trial name
- MUSIL (NCT01771445)
- Testing
- IL-1Ra
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Marc Y.Donath
Anxiety, Depressive Symptoms
The Effects of High-intensity Interval Training on Mental Health and Inflammation
The present study investigated the effects of high-intensity interval exercise training and placebo-exercise on mental health and inflammation using a randomized control trial.
- Conditions
- Anxiety, Depressive Symptoms, Inflammation
- Trial name
- NCT04118309
- Testing
- Exercise
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McMaster University
Neonatal Sepsis
Salivary C- Reactive Protein, Mean Platelet Volume and Neutrophil Lymphocyte Ratio as Diagnostic Markers for Neonatal Sepsis
To evaluate reliability of salivary C-reactive protein ,mean platelet volume , neutrophil -lymphocyte ratio , and platelet lymphocyte ratio in diagnosis of neonatal sepsis
- Trial name
- NCT04800445
- Testing
- Salivary CRP
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cytokine Storm
The Effect of D3 on Selected Cytokines Involved in Cytokine Storm in the Covid-19 Uninfected Jordanian People
The effect of Weekly 50,000 IU vitamin D3 supplements on the serum levels of selected cytokines involved in cytokine storm of Covid-19; A randomized clinical trial in the Covid-19 uninfected people with vitamin D deficiency.
- Trial name
- NCT04476745
- Testing
- Vitamin D3
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Psoriasis, Obesity
Cross-sectional Evaluation of Biological Markers of Cardiovascular Disease in Children and Adolescents With Psoriasis
Hypothesis 1: Patients with psoriasis will have clinical and laboratory assessments differing from control patients. Hypothesis 2: Patients with psoriasis will have laboratory alterations that correlate with other clinical…
- Conditions
- Psoriasis, Obesity, Cardiovascular Risk, Inflammation
- Trial name
- NCT01122095
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Oxidative Stress, Inflammation
PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers
The goal of this randomized controlled clinical trial is to evaluate whether polysaccharide peptide (PsP) supplementation from Ganoderma lucidum can modulate biomarkers of oxidative stress, inflammation, nicotine exposure, and…
- Conditions
- Oxidative Stress, Inflammation, Cigarette Smoking
- Trial name
- PSPGL (NCT07316400)
- Testing
- PsP
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
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