Clinical trials: Inflammation
Inflammation, Dyslipidemia
Effects of a Probiotics on the Health of Normal Young Males
The important role played by the GI tract microflora on the metabolic health of an individual are increasingly recognized. In this respect, the initial studies of Metchinkoff that suggested a role of fermented food (specifically…
- Trial name
- FFF (NCT02230345)
- Testing
- Probiotic yogurt, Acidified milk
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Poly Cystic Ovarian Syndrome, Polycystic Ovary Syndrome (PCOS)
Biomechanical Changes in Females with Poly Cystic Ovarian Syndrome
Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder that causes an inversion of the normal luteinizing hormone (LH) to follicle-stimulating hormone (FSH) ratio.
- Trial name
- NCT06673901
- Testing
- Measurments
- Where
- Egypt
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Peripheral Effects of Endotoxin on Insulin Resistance
The aim of the study is to isolate the direct effects of endotoxin on glucose, lipid and protein metabolism. Eight healthy volunteers are enrolled.
- Trial name
- NCT00929136
- Testing
- USP endotoxin
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Diffuse Lewy Body Disease, Dementia With Lewy Bodies
Imaging Inflammation in Patients With Parkinson's Disease Dementia or Dementia With Lewy Bodies
This study uses a special type of scan called a positron emission tomography (PET) scan to take pictures of the brain. During the PET scan, a special dye called 11C-PBR28 is injected into the body.
- Conditions
- Diffuse Lewy Body Disease, Dementia With Lewy Bodies, Parkinson's Disease Dementia
- Trial name
- NCT02702102
- Testing
- 11C-PBR28
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Columbia University
Diabetes Mellitus
Colostrum and Inflammation
Colostrum is the milk that is first produced by a mother after giving birth. It plays a key role in the normal early development of mammals by providing substances that are important for nutrition, immunological defence and…
- Trial name
- NCT04602039
- Testing
- Bovine Colostrum
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Swansea University
Cognition, Inflammation Biomarkers
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Inflammation Biomarkers, Bone Metabolism Biomarkers, Fatigue Symptom
- Trial name
- NCT07740967
- Testing
- Collagen peptides and omega-3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Postmenopause
Pharmacogenetic Study of Different Hormone Therapies in Recent Menopause Women
This is cross-over, randomized clinical trial, with objective to evaluate the effects of low-dose oral hormone therapy and non-oral hormone therapy on endothelial function markers (fibrinogen, von Willebrand factor, c-reactive…
- Trial name
- NCT01432028
- Testing
- Estradiol and Progesterone, Estradiol and Drospirenone
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Denusa Wiltgen
Inflammation
Omega-3 Fatty Acid Supplementation in Older Adults
The purpose of this study to determine whether Fish oil (Omega-3 Fatty Acid) supplementation has an impact on inflammation and lean body mass in older adults.
- Trial name
- NCT01666392
- Testing
- Omega-3 fatty acid
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Memphis
Pregnancy Related, Microbiome
Maternal & Offspring Microbiome Study
The purpose of the study is to learn how different dietary interventions affect microbiota diversity in pregnant women and the transmission of microbiota to their infants during pregnancy, birth, and postpartum.
- Conditions
- Pregnancy Related, Microbiome, Immune Function, Inflammation
- Trial name
- MOMS (NCT05123612)
- Testing
- Fiber, Fermented Foods
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depression, Inflammation
Stress and Inflammation in Late-Life Depression
Over 18% of Americans aged 65 years and older have depression. Recent evidence suggests that there is a link between depression and inflammatory disease.
- Trial name
- S&I (NCT02389465)
- Testing
- Escitalopram + Celecoxib
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Emotional Dysregulation
Emotional Regulation in Teens: Improvement of Constructive Skills
This is a prospective randomized study with twofold aim. The first aim is to evaluate the impact of a school-based intervention focused on emotional regulation skills according to Dialectical Behavior Therapy for Adolescents.
- Trial name
- EmoTIConS (NCT04349709)
- Testing
- Brief school-based DBT-A
- Where
- Italy
- Volunteers
- 462 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Inflammation, Necrosis
Antimicrobial Pulpotomy of Primary Molars
There is a lack of evidence of the long-term successful outcomes of antimicrobial endodontic treatment for primary teeth. This study intended to evaluate (by survival analysis) the effectiveness of an antimicrobial pulpotomy…
- Trial name
- NCT01010451
- Testing
- Antimicrobial pulpotomy, Calcium hydroxide pulpectomy
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Experimental Lung Inflammation
Validation of a Lung Inflammation Model in Healthy Volunteers by Radiological Tools and Glucocorticoid Treatment
The purpose of this study is to investigate the local and systemic inflammatory response and haemostatic alterations in the lungs after lipopolysaccharide (LPS) instillation and to determine the feasibility of imaging techniques…
- Trial name
- NCT01714427
- Testing
- Dexamethasone, Sterile isotonic saline
- Where
- Austria
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Chronic Renal Failure Requiring Hemodialysis
Oxidative Stress on Muscle Dysfunction in Hemodialysis Patient
In hemodialysis patient (HD) a reduction of the skeletal muscle mass and strength has previously been reported. This muscle impairment constitutes an independent prognosis factor in HD patients.
- Trial name
- POPEYE (NCT02794142)
- Testing
- renal transplantation, No intervention
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Erectile Dysfunction, Penile Prosthesis; Complications, Infection or Inflammation
Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement
The purpose of this study is to assess whether intraoperative irrigation with Irrisept is not inferior to irrigation with multiple antibiotics during placement of a first time inflatable penile prosthesis device.
- Trial name
- NCT06489431
- Testing
- Chlorhexidine, Gentamicin, Rifampin
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Immune Response
LIFEHOUSE: Description of the Tent Bucket -Immune Support
This immune support program will be an extension to the existing LIFEHOUSE program. Essential employees in Gig Harbor, WA; Colonial Heights, VA; Lenexa, KS, and Santa Fe Springs, CA, will be offered complimentary supplementation…
- Trial name
- LIFEHOUSE (NCT04734288)
- Testing
- Vit.D3 5000 IU, Immune Active
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Cancer, Chronic Lymphocytic Leukemia
Time Restricted Eating in Haematological Malignancies
The goal of this clinical trial is to learn if time restricted eating (TRE), a form of intermittent fasting, can impact health outcomes in patients with chronic lymphocytic leukemia (CLL).
- Trial name
- NCT06862323
- Testing
- Time-Restricted Eating
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Endotoxemia
The Role of Dietary Fat on Postprandial Endotoxemia in Healthy Adults
The purpose of this study was to determine the effect of different dietary fats (saturated or unsaturated) on postprandial endotoxemia and systemic low grade acute inflammation.
- Trial name
- NCT02521779
- Testing
- Low-fat Treatment Meal, Saturated-fat Treatment Meal, N-3 fat Treatment Meal
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Obstructive Sleep Apnea
Mucosal Inflammation in Children With OSA
Objectives: Variability of clinical phenotypes in childhood obstructive sleep apnoea (OSA) has prompted research for biomarkers to identify patients at risk of developing OSA-related complications.
- Trial name
- NCT06452979
- Where
- Hong Kong
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Inflammation, Muscle Recovery
The Effect of Aspalathus Linearis on Muscle Soreness and Post-exercise Recovery in Young, Physically Inactive Women
Exercise has been found to exert beneficial effect on overall health. However, it also induces muscle damage at the same time. This then leads to muscle pain, temporary inflammation and reduced muscle function.
- Conditions
- Inflammation, Muscle Recovery, Muscle Soreness
- Trial name
- NCT06561750
- Testing
- Rooibos tea, Control
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hasselt University
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