Clinical trials: Inflammation
Dysmenorrhea, Inflammation
The Effects of Exercise and Probiotics on Dysmenorrhea and Microbiome
The study try to investigate the possible effects of exercise and probiotics supplementation on dysmenorrhea amelioration from the perspective of microbiome.
- Conditions
- Dysmenorrhea, Inflammation, Microbial Substitution
- Trial name
- NCT05326217
- Testing
- Aerobic exercise, Resistant exercise
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Infant Development
Blueberry Intake and Infant Gut Health
The objective of this project is to investigate the effects of blueberries on gut microbiota, inflammation and innate immunity in breastfed infants during early complementary feeding (~5 to 12 months of age).
- Trial name
- NCT05006989
- Testing
- Blueberry Powder
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Covid19
DNA Damage and Oxidative Stress in Hospitalized COVID-19 Patients
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic challenging health systems worldwide.
- Trial name
- ABCD (NCT04784468)
- Testing
- No intervention
- Where
- Austria
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Infertility, Female, Infertility Unexplained
Pro-inflammatory Cytokines and Implantation Process in Women With Primary Idiopathic Infertility
Infertility is a common, worldwide problem. In about 20% of couples, the causative agent of infertility cannot be identified after routine diagnostic tests.
- Conditions
- Infertility, Female, Infertility Unexplained, Inflammatory Response
- Trial name
- NCT05190250
- Testing
- Pipelle biopsy
- Where
- Poland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Pruritus
Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch
The purpose of this project is to investigate the effect of capsaicin-induced neurogenic inflammation with three different intensities on itch subsequently induced by histamine and cowhage.
- Trial name
- NCT02769910
- Testing
- Capsaicin 24 Hours, Capsaicin 1 Hour, Qutenza Demo Patch
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hjalte Holm Andersen
Diabetes, Hypertension
FFA Hypertension and Inflammation in Lean and Obese Subjects
Although a large number of obese patients develop high blood pressure, the cause is unknown. The purpose of this study is to look at the effect of high fatty acids (a type of fat) in the development of high blood pressure in…
- Conditions
- Diabetes, Hypertension, Obesity
- Trial name
- FFAADA (NCT00721617)
- Testing
- Intralipid 20%, Normal Saline, Oral fat load
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Gingivitis
Effectiveness of the Use of Dental Floss
Bacterial plaque-induced gingivitis is considered the most common oral disease in dentate individuals and the most frequent type of periodontal disease.
- Trial name
- NCT04909840
- Testing
- Instructions oral hygiene with toothbrush plus dental floss, Instructions oral hygiene with toothbrush only
- Where
- Brazil
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Osteoarthritis, Knee
Combination of Curcuminoid With Acupressure for Inflammation and Pain in the Elderly With Osteoarthritis Genu
The goal of this clinical trial is to to investigate the efficacy of acupressure and standardized curcuminoids from turmeric extract to inflammatory markers, endorphin hormones in the blood and quality of life in elderly patient…
- Trial name
- NCT06105840
- Testing
- Acupressure and Standardized Curcuminoid from Turmeric Extract
- Where
- Indonesia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Toxic Shock Syndrome Staphylococcal
Phase I STEBVax in Healthy Adults
The main purpose of this study is to test the safety of a new vaccine, STEBVax, which may lead to a useful treatment for toxic shock syndrome.
- Trial name
- NCT00974935
- Testing
- Aluminum hydroxide, STEBVax vaccine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Inflammation
Nitrosomonas Eutropha on Nitrolipids in the Skin
We are looking to see how the addition of nitrosomonas alters the presence of nitrolipids and inflammatory cytokines on the skin.
- Trial name
- NCT02938650
- Testing
- Nitrosomonas eutropha
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Sepsis, Severe Sepsis
Subpopulation-Specific Sepsis Identification Using Machine Learning
The focus of this study will be to conduct a prospective, randomized controlled trial (RCT) at Cape Regional Medical Center (CRMC), Oroville Hospital (OH), and UCSF Medical Center (UCSF) in which a subpopulation-optimized…
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- NCT03644940
- Testing
- CustomSight
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dascena
Pregnancy, Obesity
Advanced MRI for Uteroplacental Flow, Perfusion, Oxygenation & Inflammation
The purpose of the study is to develop advanced ultrasound (U/S) and Magnetic Resonance Imaging, known as MRI to study uteroplacental health.
- Conditions
- Pregnancy, Obesity, Preeclampsia
- Trial name
- NCT02791568
- Testing
- Ultrasound Scan, MRI Scan, Ferumoxytol
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Inflammation
Effect of Glucose Load on Expression of Advanced Glycation End Products in Women Screened for Gestational Diabetes
The investigator's main objective is to analyze the effects of a routine prenatal care screening tool (glucola test for gestational diabetes) on maternal inflammation through assessment of maternal circulatory biomarkers and…
- Trial name
- NCT03029546
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Gut Inflammation, Hypertension
Gut Organoid and Microbiome Interactions in Hypertension
The study compared basic properties of gut epithelia of hypertensive and normotensive reference subjects. The study determined if there are fundamental differences in the gut epithelium in hypertension compared to normotension.
- Trial name
- NCT04497727
- Testing
- Gene Expression
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Florida
Shift-Work Related Sleep Disturbance, Inflammation
Markers of Inflammation and of the Pro-thrombotic State in Hospital Shift and Day Workers
The goal of this observational study is to learn if acutely and/or chronically altered sleep induces inflammation and/or a pro-thrombotic state (a tendency to form clots) in hospital workers who either work in shifts or are…
- Conditions
- Shift-Work Related Sleep Disturbance, Inflammation, Hemostatic Disorder, Sleep Disorder
- Trial name
- IPNO (NCT05775731)
- Testing
- Tests for markers of inflammation and activated hemostasis
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Cataract, Myopia
Measurement of Antioxidant Activity on Postoperative Inflammation in Patients Undergoing Ophthalmic Surgery
This trial hypothesized that novel laser refractive surgery techniques (PRK, LASIK, SMILE) or laser-assisted cataract surgery (FLACAS) could suppress postoperative inflammation and improve recovery in patients by reducing…
- Trial name
- NCT05905237
- Testing
- Cataract surgery, Femtosecond-LASIK, SMILE
- Where
- 2 sites in Taiwan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Immune Response
LIFEHOUSE: Description of the Tent Bucket -Immune Support
This immune support program will be an extension to the existing LIFEHOUSE program. Essential employees in Gig Harbor, WA; Colonial Heights, VA; Lenexa, KS, and Santa Fe Springs, CA, will be offered complimentary supplementation…
- Trial name
- LIFEHOUSE (NCT04734288)
- Testing
- Vit.D3 5000 IU, Immune Active
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Metabolic Syndrome, Overweight
Systematic Review and Meta-analysis of the Differential Effects of DHA and EPA on Inflammation
According to the World Health Organization, cardiovascular diseases (CVDs) are the number 1 cause of death globally. Systemic and local tissue inflammation is now recognized as a key etiological process leading to CVD.
- Conditions
- Metabolic Syndrome, Overweight, Obesity, Chronic Inflammation
- Trial name
- NCT03520556
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma, Allergic Asthma
Asthma Inflammation Research
The overall goal of the Asthma Inflammation Research [AIR] Translational Program is to create an integrated multidisciplinary team for the focused purpose of development of diagnostic and prognostic tests informative for airway…
- Conditions
- Asthma, Allergic Asthma, Non-allergic Asthma
- Trial name
- AIR (NCT01536522)
- Testing
- Nutritional approach for asthma, Low Caloric Shake, whole lung allergen challenge
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Dyslipidemia, Insulin Resistance Syndrome
Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults
The prevalence of overweight and obesity remains epidemic in the United States, with some of the highest rates seen in older adults.
- Conditions
- Dyslipidemia, Insulin Resistance Syndrome, Hypertension, Inflammation Chronic
- Trial name
- NCT07221279
- Testing
- Step counts for predictable changes in body weight/compositon and cardiometabolic risk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
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