Clinical trials: Inflammation Function
Persistent Postural Perceptual Dizziness
Using Glialia for Treating Persistent Perceptual Postural Dizziness
This pilot study will involve 30 participants recruited from the Santa Lucia Foundation IRCCS, including 20 patients diagnosed with Persistent Perceptual Postural Dizziness (PPPD), and might or might not have previously…
- Trial name
- GLI-PPPD (NCT06741358)
- Testing
- Glialia, Control
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Cognitive Impairment, Cognitive Decline
A Prospective, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of LasoperinTM on Cognitive Function in Healthy Adults
The potential impact of various dietary ingredients to improve cognitive function, mood, well-being, and overall levels of affects are largely undetermined.
- Conditions
- Cognitive Impairment, Cognitive Decline, Cognition Disorders in Old Age, Well-Being, Psychological
- Trial name
- COG (NCT05994391)
- Testing
- LasoperinTM, Placeo
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Atherosclerosis
Inflammation, Viral Replication, and Atherosclerosis in Treated HIV Infection
This is a longitudinal observational study of HIV-infected patients and HIV-negative control patients that is being conducted to learn more about immunologic factors, inflammation, and cardiovascular risk in patients with HIV…
- Trial name
- NCT01519141
- Where
- United States
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vascular Health, Autonomic Function
Vascular and Neuro-inflammatory Effects of Endurance Exercise Training in African Americans
The purpose of this study is to test the effects of endurance exercise training on arterial structure and function, and to examine potential mechanisms producing changes in arterial structure and function in young (18-35 years of…
- Trial name
- VINE (NCT01024634)
- Testing
- Endurance Exercise
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Severe Sepsis, Critical Illness
Ultrasound Measurement of Reactive Hyperemia in Critical Care
The investigators hypothesize that doctors and nurses can undergo a brief period of training and then use ultrasound to accurately measure blood flow in a forearm artery after a brief period when this flow is interrupted with a…
- Trial name
- URHC (NCT01726595)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Neonatal Sepsis, Markers
Tissue Doppler Echocardiographic Assessment of Cardiac Function in Neonatal Sepsis
1. To assess myocardial function in neonates with sepsis using tissue doppler echocardiography. 2. To assess sepsis induced cardiac dysfunction. 3.
- Trial name
- NCT07572916
- Testing
- cardiac troponin, and blood culture
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
HIV Infection, Cardiovascular Disease
The Role of Inflammation and Aging in HIV-Associated Cardiovascular Risk
It is the central hypothesis of the investigators study that HIV disease is a pro-inflammatory condition, and that years of inflammation result in premature "aging' of the immune system ("immunosenescence").
- Conditions
- HIV Infection, Cardiovascular Disease, Inflammation
- Trial name
- NCT01333644
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Inflammatory Bowel Diseases
Assessing Cardiovascular Dysfunction Pre- & Post-treatment in Inflammatory Bowel Diseases
The aim of this study is to compare medical and surgery treatment in IBD patients and healthy controls, by assessing the endothelial and cardiac function and the inflammation status.
- Trial name
- NCT03615287
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Athens
Oxidative Stress, Inflammation
Effects of Magnesium and Spinning Training on Echocardiographic, Inflammatory, and Aerobic Outcomes
Regular aerobic exercise may improve cardiorespiratory fitness while modulating systemic inflammation and oxidative stress. Spinning, as a structured indoor cycling modality, provides a practical aerobic exercise model with…
- Conditions
- Oxidative Stress, Inflammation, Physical Fitness, Echocardiography
- Trial name
- NCT07662954
- Testing
- Spinning Training, Magnesium Supplementation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
To Determine Whether Estrogen Influences the Effects of Training on Glycemic Control and Insulin Sensitivity
Does Estrogen Blunt the Effects of Exercise Training on Glycemic Control
Previous research has found that males and females respond differently to exercise training, particularly with respect to improvements in blood sugar control and immune system health.
- Trial name
- NCT07791394
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Healthy
The Effect of AGE on the Immune System
This is a nutritional intervention study using healthy overweight/obese humans to investigate if a supplement made from aged garlic extract has an impact on immunity.
- Trial name
- EAGESIS II (NCT01959646)
- Testing
- Aged Garlic Extract Supplementation Group, Standard for Groups
- Where
- 2 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Florida
Renal Transplant Failure and Rejection, Inflammation
The Effect of Biomarkers of Inflammation on Graft Function in Kidney Transplantation
The aim of the study was to investigate the relationship of inflammation markers with postoperative graft function and mortality in patients undergoing kidney transplantation.
- Trial name
- NCT05753488
- Testing
- graft function
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Cardiovascular Health, Obesity
Effects of the Atkins Diet Versus a Low Fat Diet on Inflammation
The purpose of this research is to assess the effects of a low-carbohydrate (modified Atkins) diet versus a low fat (Heart Healthy) diet on cardiovascular health.
- Trial name
- NCT00993278
- Testing
- Low-Carbohydrate (Modified Atkins) Diet, Low-Fat (Heart Healthy) Diet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Coronary Artery Disease
Intravenous Fish Oil in Critically Ill Cardiac Patients
A large body of evidence has accumulated showing that n-3 PUFAs exert extensive cardiac effects. The development of commercial solutions of FO opens perspectives for therapeutic applications in patients with acute cardiac…
- Trial name
- FO-cardiac (NCT00516178)
- Testing
- Fish oil emulsion, Saline
- Where
- 2 sites in Switzerland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Functional Dyspepsia
Neuro-immune Interactions and PPI
Prospective interventional study on duodenal neuro-immune interactions in healthy volunteers and functional dyspepsia patients and the effects of PPI
- Trial name
- NCT04713969
- Testing
- Pantoprazole 40mg
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Immune System Processes, Inflammatory Activation and Modulation
The Sounds of Compassion: Testing How Specific Elements of Meditation Change Daily Life
Important health benefits of meditation may be conferred as much by what people actually do and say in their daily lives as by how they self-perceive the effect of training on their behavior and emotions.
- Conditions
- Immune System Processes, Inflammatory Activation and Modulation, ANS Function
- Trial name
- NCT01643369
- Testing
- Cognitive-Based Compassion Training, Adult Health Education Curriculum, Mindful Attention Training
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Hypertension
Effect of Polyphenols Combined to L-citrulline on Ambulatory Blood Pressure
The general objective of this project is to investigate the chronic effect of consuming supplements combining polyphenols from cranberry and grape seed extracts and L-citrulline (Nitric Oxide Ultra capsules, Pure Encapsulations…
- Trial name
- NCT03679195
- Testing
- NO Ultra
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Laval University
Cognitive Function, Cardiopulmonary Function
Commuter Air Pollution Intervention Study
Traffic related air pollution is a well-recognised and much studied contributor to smog and is linked to a number of adverse health outcomes.
- Conditions
- Cognitive Function, Cardiopulmonary Function, Saliva Stress Hormones, Air Pollution Exposure
- Trial name
- CAPI (NCT02277002)
- Testing
- Cabin Air Filtration
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Health Canada
Sepsis, SIRS(Systemic Inflammatory Response Syndrome)
Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients
The imbalance between anti- and pro-inflammation often occurs in patients with sepsis. And continuous such imbalance could lead to immunoparalysis, which is characterized by loss of delayed type hypersensitivity, failure of…
- Trial name
- NCT01801839
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Insulin Resistance, Endothelial Dysfunction
Effect of Continuous GHRP-3 Infusion at on GH-IGF-I System, Blood Pressure, Glucose, and Insulin Resistance
The hypothesis is that GHRP-3 will exert beneficial effects on endothelial function and insulin resistance in older men and women via hormonal (GH, IGF-I, IGFBP-3,-1, insulin) and non-hormonal actions (anti-inflammatory).
- Trial name
- NCT00846872
- Testing
- GHRP-3 low dose, GHRP-3 high dose, Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tulane University Health Sciences Center