Clinical trials: Inflammatory Bowel System
Crohn's Disease
Use of Combined Measurements of Serum Infliximab and Anti-infliximab Antibodies in the Treatment of Patients With Crohns Disease Failing Infliximab Therapy
To compare treatment outcome in patients with Crohn's disease with secondary loss of response to infliximab (i.e. initial good response follow by loss of response) treated according to current standards based only on clinical…
- Trial name
- NCT00851565
- Testing
- Measurement of serum infliximab and anti-infliximab antibodies, Treatment according to current standards without knowledge of serum infliximab and anti-infliximab Ab status
- Where
- 8 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Copenhagen University Hospital at Herlev
Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer
The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients
The study was designed as a prospective, observational study. Pediatric patients under 18 years of age scheduled for peripheral vascular access placement during day-case surgery or non-operating room anesthesia (NORA) will be…
- Conditions
- Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer, Cataract, Crohn's Disease
- Trial name
- NCT07315711
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sibel Seçkin Pehlivan
Ulcerative Colitis (UC)
Dose-Evaluation Study of the Efficacy and Safety of TLA Gut™ Leukapheresis Treatment in Patients With Ulcerative Colitis
An open-label, randomised, multi-centre, dose evaluation study of the efficacy and safety of TLA Gut™ leukapheresis treatment in patients with UC.
- Trial name
- NCT04550130
- Testing
- TLA Gut™
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- TLA, Targeted Immunotherapies AB
Inflammatory Bowel Disease
Genetic Studies of Inflammatory Bowel Disease
This study will examine the existence of genetic regions that are believed to bring about a risk for inflammatory bowel disease (IBD), with its subtypes of Crohn's disease and ulcerative colitis.
- Trial name
- NCT00340444
- Where
- 5 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Acute Appendicitis
Comparative Study on the Diagnostic Validity of the Alvarado Score, Appendicitis Inflammatory Response (AIR), and Adult Appendicitis Score (AAS) in Acute Appendicitis at East Lancashire Hospitals NHS Trust (ELHT)
This retrospective observational study aims to compare the diagnostic accuracy of Alvarado Score, Appendicitis Inflammatory Response (AIR) Score, and Adult Appendicitis Score (AAS) in predicting histologically confirmed acute…
- Trial name
- DV-AAA ELHT (NCT07804238)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Inflammatory Bowel Diseases
Preoperative Oral ImmunoNuTrition to Improve Surgical Outcomes for IBD Patients (PINT)
The central focus of this trial is to understand the effectiveness of Preoperative Immunonutrition (PINT) in improving surgical outcomes for patients with inflammatory bowel disease (IBD).
- Trial name
- PINT (NCT03333148)
- Testing
- Nestle IMPACT Immunonutrition, Arm B- Standard of Care
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Ulcerative Colitis
Azathioprine Based on Endoscopy After Clinical Remission in Moderate to Severe Ulcerative Colitis
The aim of this study is to determine whether azathioprine is effective for mucosal healing in UC patients who achieved clinical remission by the first course of corticosteroids but not mucosal healing in endoscopy.
- Trial name
- ACE (NCT02579733)
- Testing
- Azathioprine
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Kyungpook National University Hospital
Inflammatory Bowel Diseases
VeDOlizumab PERsistence in IBD Patients After Switching From Intravenous to Subcutaneous Administration : a Real-life Multicenter Study (DOPER)
Descriptive : A 12-months multicenter, observational, prospective cohort study. Population : IBD patients under stable clinical and biological remission will be proposed to switch from the IV vedolizumab to the SC vedolizumab as…
- Trial name
- DOPER (NCT05158517)
- Testing
- Subcutaneous vedolizumab
- Where
- France
- Volunteers
- 349 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Ulcerative Colitis (UC), Ulcerative Colitis
Desloratadine in Patients With Ulcerative Colitis
The purpose of this study is to investigate safety and therapeutic efficacy of antihistamine (desloratadine) on inflammation and disease activity when administered as adjuvant therapies with the traditional therapy…
- Trial name
- UC (NCT07333716)
- Testing
- Desloratadine, mesalamine
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Molecular Analysis
Report of a New Method Used to Identify the Bacteria Present in a Human Colon Biopsy Sample
The method used for the biopsy analysis may be able to provide important insights into the complex microbial communities found in the human colon or in complex human infections.
- Trial name
- NCT00882752
- Testing
- molecular analysis
- Volunteers
- 1 people
- Sponsor
- Southwest Regional Wound Care Center
IBD and Renal Involement, Chronic Kidney Disease
Renal Dysfunction in Patients With Inflammatory Bowel Disease and the General Population (NEPHRO-IBD)
The NEPHRO-IBD study is a multicenter prospective observational study designed to evaluate the prevalence of renal dysfunction and renal complications in adult patients with inflammatory bowel disease (IBD) compared with…
- Conditions
- IBD and Renal Involement, Chronic Kidney Disease, Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis)
- Trial name
- NEPHRO-IBD (NCT07593352)
- Testing
- Prospective assessment of the prevalence of kidney disease and/or renal complications in patients with IBD/the general population based on routine laboratory test and abdominal ultrasound.
- Where
- Poland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i Administracji
Morbus Crohn, Colitis, Ulcerative
Acupuncture in Pediatrics and Adolescents With Chronic Inflammatory Bowel Diseases
Chronic inflammatory bowel disease (CIBD) with its prevalence of 2.6 million people in Europe is diagnosed in 25% before the age of 18 years.
- Trial name
- NCT04488198
- Testing
- Acupuncture
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Neonatal Sepsis, Necrotizing Enterocolitis
Bovine Lactoferrin and Neonatal Survival in Low Birth Weight Babies.
Pakistan has the third highest number of neonatal deaths worldwide. During the last two decades (1990-2013), neonatal mortality rate in the country has declined by only 1.0% per year.
- Trial name
- NCT03431558
- Testing
- bLF (Bovine lactoferrin)
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Crohn's Disease
Study To Test Whether PF-00547659 Is Safe And Improves Disease Symptoms In Patients With Crohn's Disease
Adults with Crohn's disease that is clinically active despite conventional treatment will be eligible for this study. Patients may receive one of three doses of PF-00547659 (experimental drug) or placebo (inactive drug).
- Trial name
- OPERA (NCT01276509)
- Testing
- PF-00547659 SC injection
- Where
- 137 sites in United States, Austria and 14 more
- Volunteers
- 265 people
- Sponsor
- Shire
Metabolic Syndrome
Pomegranate Consumption by Poly-medicated Metabolic Syndrome Patients
The objective is to evaluate whether the medication in polymedicated metabolic syndrome patients could determine the effects of a pomegranate extract on i) metabolic markers, ii) inflammatory markers, and iii) the modulation of…
- Trial name
- NCT04075032
- Testing
- Pomegranate extract
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- National Research Council, Spain
Crohn Disease, Ulcerative Colitis
The PRECIOUS Study: Predicting Crohn's & ColitIs Outcomes in the United States
A multi-center observational study based at referral centers and community hospitals within the US. Patients' blood will be collected at enrollment for testing with PredictSURE IBD™, which will occur at a later date.
- Conditions
- Crohn Disease, Ulcerative Colitis, IBD, Inflammatory Bowel Diseases
- Trial name
- NCT03952364
- Testing
- PredictSURE IBD™
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- PredictImmune Ltd
Ulcerative Colitis
Tolerability and Efficacy of Sodium Picosulfate/Magnesium Citrate Versus PEG/Ascorbic Acid in Ulcerative Colitis Patients
Ulcerative colitis is a chronic condition that results in the inflammation of the colon and rectum. Patients suspected to have ulcerative colitis are diagnosed via colonoscopy.
- Trial name
- NCT03581149
- Testing
- Sodium Picosulfate/Magnesium Citrate Laxative, 2L polyethylene glycol/ascorbic acid
- Where
- Lebanon
- Volunteers
- 68 people
- Sponsor
- American University of Beirut Medical Center
Crohn Disease of Ileum
Ileocolic Resection for Complex Crohn's Disease
Laparoscopic ileocolic resection is the preferred surgical approach for patients with ileocecal Crohn's disease (CD). Objective of this study was to evaluate the efficacy of a minimally invasive gas-less ileocolic resection in…
- Trial name
- NCT03950726
- Testing
- ileocolic resection
- Volunteers
- 27 people
- Sponsor
- University of Roma La Sapienza
Healthy Nutrition
Dietary Impact on Intestinal Sulfate Metabolism
This is a 5-week crossover pilot study of 15 highly motivated healthy volunteers who will consume two 7-day intervention diets: 1) a diet low in sulfur-containing amino acids (Low-S diet), emphasizing plant-based foods and fat…
- Trial name
- NCT05333900
- Testing
- Plant-Based Diet then animal-based diet, Animal-based diet then plant-based diet
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Colitis, Ulcerative
A Safety and Effectiveness Study of Golimumab in Japanese Patients With Moderately to Severely Active Ulcerative Colitis.
The purpose of this study is to evaluate safety and effectiveness of golimumab in Japanese participants with moderately to severely active ulcerative colitis.
- Trial name
- NCT01863771
- Testing
- Golimumab
- Where
- 38 sites in Japan
- Volunteers
- 144 people
- Sponsor
- Janssen Pharmaceutical K.K.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.