Clinical trials: Inflammatory Conditions
Decay, Dental, Missing Teeth
Relationship Between Oral Findings and Salivary Factors in Sars-Cov-2 Patients
Two hundred individuals will be formed according to the study and control groups: Group-1: coronavirus 2 (Covid-19) (+) patients (n=100) and Group-2: Healthy individuals (in which the volunteers will be included due to group-1)…
- Conditions
- Decay, Dental, Missing Teeth, COVID-19, Cytokine Storm
- Trial name
- NCT05476848
- Testing
- ELISA test for Cytokines
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Ege University
Delivery, Cesarean Delivery
Comparison of Inflammatory Responses Subsequent to Different Cesarean Section Techniques
In this study, the investigators aimed to find out whether there are any differences in inflammatory reactions occured subsequent to two different cesarean delivery techniques; modified Misgav-Ladach vs Pfannenstiel-Kerr…
- Conditions
- Delivery, Cesarean Delivery, Inflammation
- Trial name
- C/S (NCT02976311)
- Testing
- cesarean section(C/S) via the modified Misgav-Ladach technique, cesarean section via the Pfannenstiel-Kerr technique
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Premature Ventricular Complexes, Diet Quality
Premature Ventricular Complex and Diet Inflamatuar Index
The aim of this study is to evaluate differences in energy, macro- and micronutrient intakes, dietary characteristics, quality of life, and biochemical parameters between individuals with and without premature ventricular…
- Conditions
- Premature Ventricular Complexes, Diet Quality, Biochemical Markers, Life Quality
- Trial name
- PVT (NCT07870109)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Sepsis
Detection of Sepsis Occurrence by Using Blood Fluorescence
This study adopted a case-control study method to explore a reagent-free, highly sensitive, and frequently screened blood fluorescence metabolite analyzer for sepsis, which can detect the emergence of inflammatory free radicals…
- Trial name
- NCT06745115
- Testing
- Blood fluorescence metabolite analyzer
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Inflammation
Inflammatory Responses to Acute and Chronic Opioid Exposure in Humans
We aim to examine the extent to which inflammation is affected by acute and chronic opioid exposure.
- Trial name
- NCT01749826
- Testing
- Morphine Sulfate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy
Bioavailability Study Of PF-06651600 In Healthy Subjects
PF-06651600 is being developed for treatment of inflammatory bowel disease. This study will test the bioavailability of a solid dose formulation of PF-06651600 compared to an oral solution formulation under fasting conditions and…
- Trial name
- NCT02684760
- Testing
- PF-06651600
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pfizer
High Altitude
Effects of Non-steroidal Anti-inflammatory Drugs (NSAIDS) on Acclimatization to High Altitude
Ibuprofen is often taken by travelers to high altitude to treat the symptoms of acute mountain sickness such as headache and malaise.
- Trial name
- NCT02233582
- Testing
- Ibuprofen, Sugar pill
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Toxic Shock Syndrome Staphylococcal
Phase I STEBVax in Healthy Adults
The main purpose of this study is to test the safety of a new vaccine, STEBVax, which may lead to a useful treatment for toxic shock syndrome.
- Trial name
- NCT00974935
- Testing
- Aluminum hydroxide, STEBVax vaccine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Castleman Disease, Angiofollicular Lymphoid Hyperplasia
Unlock the Cell: Castleman's Disease Flow Cytometry Study
Castleman disease, a rare lymphoproliferative disorder, is characterized by inflammatory cytokine production and multiple organ system dysfunction.
- Conditions
- Castleman Disease, Angiofollicular Lymphoid Hyperplasia, GLNH, Hyperplasia
- Trial name
- NCT02853968
- Testing
- Blood draw/buccal swab
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Uremia, Inflammation
Influence of Oral Vitamin C Supplement on the Inflammation Status in Dialysis Patients
Subclinical inflammation is a common phenomenon in patients receiving maintenance hemodialysis (MHD). This is because various pro-inflammatory cytokines are promoted due to metabolic acidosis, volume overload, and / or…
- Trial name
- NCT01356433
- Testing
- oral vitamin C
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Sepsis, Endotoxemia, Immunosuppression
The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells
We will investigate whether human endotoxemia induces changes in human bone marrow cells and their downstream effector cells. To comprehensively investigate underlying mechanisms behind functional and transcriptional changes in…
- Trial name
- LPS-BM (NCT05570643)
- Testing
- LPS
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Sepsis
Circulating microRNAs as Biomarkers of Sepsis
MicroRNA has been demonstrated to play a crucial role in regulating cell processes. Recently, microRNA was identified to exist in human serum or plasma, and it might be related to certain diseases.
- Trial name
- NCT00862290
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Psoriatic Arthritis, Arthritis
99mTc-anti-TNF-alpha Scintigraphy in the Evaluation of Inflammatory Processes Activity
Rheumatoid and psoriatic arthritis patients benefit from anti-TNF-α therapy, once it is effective in reducing joint and skin manifestations in 60-70% of patients with inflammatory articular joint and skin diseases.
- Trial name
- NCT02134613
- Testing
- 99mTc-anti-TNF-alpha Scintigraphy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Sepsis, Infection
Biomarkers in Infection
The purpose of this investigation is to evaluate how early biomarkers of infection and inflammation perform in identifying patients at risk for poor outcome in sepsis and septic shock.
- Conditions
- Sepsis, Infection, Inflammation
- Trial name
- NCT02545478
- Where
- 2 sites in United States
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Sepsis
abioSCOPE PSP Reference Range Study; Extension of AB-PSP-003
This is a monocentric, prospective, biomarker-result-blinded observational study evaluating immunoassay measurements of pancreatic stone protein (PSP) performed on Abionic's abioSCOPE device with the PSP assay on generally…
- Trial name
- AB-PSP-007 (NCT05849935)
- Testing
- abioSCOPE
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Abionic SA
Critical Illness, Septic Shock
Microcirculatory Alterations in Critical Disease: New Ultrasound Technology
Aim of this study is (1) to test and further develop a new non-invasive ultrasound method, and (2) to gain new insight into microcirculatory alterations during critical disease, particularly in critical septic shock patients.
- Trial name
- SepCease (NCT03311568)
- Testing
- ultrasound for microcirculatory assessment
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Pro- and Anti-inflammatory Cytokines in PCOS
The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin…
- Trial name
- NCT06793085
- Testing
- Measurement of interleukin-6 (il-6) concentration in blood serum, Measurement of fasting tumor necrosis factor α (TNF-α) concentration, Measurement of interleukin-18 (il-18) concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Polyneuropathies, Septic Shock
Electrical Muscle Stimulation in the Development of Acquired Weakness in Patients With Severe Sepsis and Septic Shock
The aim of this study is to compare the effect of EMS and conventional physical therapy on strength and muscle mass and development in adult patients with severe sepsis and septic shock.
- Conditions
- Polyneuropathies, Septic Shock, Muscle Weakness
- Trial name
- NCT03765489
- Testing
- electrical muscle stimulation, conventional physical therapy
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Chile
Inflammation, Inflammatory Response
Inflammatory Response to OMT
Investigators will evaluate inflammation before and after an osteopathic manipulative treatment (OMT) in healthy adults, 18-59 years of age. Investigators will look at proteins in the blood called "cytokines".
- Trial name
- NCT06820684
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pacific Northwest University of Health Sciences
Cardiovascular Disease, Healthcare Associated Infectious Disease
Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (HAI)_2
The investigators will conduct qualitative interviews of hospital personnel regarding HAI prevention practices, and use coded data from these interviews to assist in developing standardized practices.
- Conditions
- Cardiovascular Disease, Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection, Deep Sternal Infection
- Trial name
- NCT02073760
- Testing
- There is no intervention. The investigators are interviewing cardiac surgery staff with knowledge of infection prevention.
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Michigan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.