Clinical trials: Inflammatory Marker
Major Depressive Disorder
Mindfulness-Based Cognitive Therapy Effect on Depression and C-Reactive Protein Levels After 8 Weeks of Treatment
This study will investigate the efficacy of an 8-week course in Mindfulness-Based Cognitive Therapy (MBCT) for adults with major depressive disorder (MDD) by ;measuring change from baseline to completion of treatment at 8 weeks…
- Trial name
- NCT02385786
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
IBD-Inflammatory Bowel Disease
Inflammatory Marker in Ibd and Peripheral Arthritis
The Objective Of This Study Is To Estimate The Correlation Between Disease Activity In IBD, Inflammatory Markers And Peripheral Arthritis After Exclusion Of Other Causes Arthritis
- Trial name
- NCT05705232
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Alzheimer's Disease
BONSAI: Biomarkers of Nonsteroidal Anti-Inflammatories
The purpose of this study is to test the effect of ibuprofen on the levels of a number of different proteins (called biomarkers) in cerebrospinal fluid (CSF), blood, and urine to see whether ibuprofen can influence certain…
- Trial name
- NCT00239746
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Vestibular Disorder, Headache
The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain Injury
Test the hypothesis that a certain set of osteopathic manipulation procedures preformed on patients with mild to moderate traumatic brain injury will result in accelerated rates of recovery assessed using vestibular function…
- Conditions
- Vestibular Disorder, Headache, Traumatic Brain Injury
- Trial name
- NCT03163901
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Multiple Trauma
Inflammatory Response After Muscle and Skeleton Trauma
The purpose of this study is to determine the inflammatory response after multiple trauma in humans.
- Trial name
- IRAMST (NCT00710411)
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Obesity
Effect of Whole-grape Powder on Body Composition, Fat and Bone Serum Biomarkers in Postmenopausal Women
The purpose of the study is to provide whole-grape powder or a placebo as a supplement to postmenopausal women for 12 weeks to determine the effects on body composition and bone formation.It is hypothesized that 12 weeks of…
- Trial name
- NCT01717820
- Testing
- Freeze-dried whole-grape powder
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Herper Zoster
Biomarker Study in Patients With Herpes Zoster
Investigators performed this study to investigate the expression levels inflammatory cytokine and neurotransmitters (calcitonin gene-related peptide (CGRP), substance P (SP), vasoactive intestinal peptide (VIP), and β-endorphin)…
- Trial name
- NCT05685797
- Testing
- Herpes zoszter (acute)with inter vention
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Keimyung University Dongsan Medical Center
Depression, Postpartum
Immune/Inflammatory Biomarkers in Postpartum Depression
This will be a very straightforward study assessing changes of immune/inflammatory peripheral biomarkers before/after delivery with postpartum mood and the psychopathological features of postpartum depression (PPD), and with MRI…
- Trial name
- PPDINFLAME (NCT05784116)
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Vaginosis, Bacterial
Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers
It is not known if the use of NuvaRing® alters these innate and inflammatory biomarkers of inflammation. Hypothesis: The hypothesis is that NuvaRing® will alter inflammatory biomarkers of inflammation, such as vaginal defensin…
- Trial name
- NCT01448291
- Testing
- Etonogestrel /Ethinyl Estradiol Contraceptive Vaginal Ring
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Inflammatory Bowel Disease (IBD), Crohn's Disease (CD)
Faecal Calprotectin as a Potential Non-invasive Inflammatory Marker in Pregnancy and Inflammatory Bowel Disease
When women with rheumatoid arthritis become pregnant 75% of them will go into remission, despite stopping medication. This phenomenon is not well understood and is not seen in other inflammatory conditions.
- Conditions
- Inflammatory Bowel Disease (IBD), Crohn's Disease (CD), Ulcerative Colitis (UC), Pregnancy
- Trial name
- PREGCAL (NCT02778464)
- Where
- United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Sjogren's Syndrome
Assessment of Inflammatory Biomarkers Expressed in a Sjogren's Population: Effect of a Topical Steroid Intervention
The primary purpose of this study is to quantify the change in expression of biomarkers on the ocular surface of Sjogren's Syndrome participants after treatment with Maxidex.
- Trial name
- NCT00631358
- Testing
- Maxidex, No treatment
- Where
- 2 sites in Canada
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Lipedema, Inflamation
Investigation of Systemic Inflammation Markers in Lipedema
The aim of this study is to evaluate systemic inflammation in individuals with lipedema using hematological and biochemical inflammation indices and to examine the relationship between these indices and clinical findings.
- Conditions
- Lipedema, Inflamation, Inflammation Biomarkers, Obesity & Overweight
- Trial name
- NCT07787234
- Testing
- Clinical parameters, Laboratory parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Inflammatory Bowel Diseases
Biobank - Investigating the Gut Microbiota, Genetics, Epigenetics and Metabolites
Inflammatory bowel disease (IBD) affects 1 in 500 to 1,000 people in the West. Previously a disease predominantly of the West, there is now a marked increase in the incidence of ulcerative colitis (UC) and Crohn's disease (CD) in…
- Trial name
- NCT03855657
- Where
- Hong Kong
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
High Blood Pressure
Microcirculation and Inflammatory Markers in Patients With Resistant, Stages 1/2 Hypertension and Normal Blood Pressure
Nailfold videocapillaroscopy (NVC), Venous occlusion Plethysmography (VOP) and inflammatory biomarkers have been used to study endothelial function in patients with resistant hypertension, stages 1 and 2 hypertension and…
- Trial name
- MICRORAH (NCT02759276)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Daniel Alexandre Bottino
Gingivitis
Dietary Diversities: Exploring the Influence of Keto Diet and Intermittent Fasting on Oral Health and Salivary Inflammatory Biomarkers
This study aims to investigate the impact of short term, two distinct dietary interventions, namely the Keto diet and Intermittent Fasting on oral health by measuring the severity of: Periodontal diseases (Gingivitis).
- Trial name
- NCT06597708
- Testing
- keto diet, intermittent fasting with calorie restriction
- Where
- Iraq
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Major Depressive Disorder
Study on the Effect of PRKCB1 Modulating Inflammatory Factors and the Role for Developing Major Depressive Disorder
Depressive disorder is known as being accompanied with the activation of immune system which could lead to a series of changes including the neuron apoptosis, synapses transmission inhibition and emotional symptoms.
- Trial name
- NCT03899194
- Testing
- fish oil capsules, escitalopram
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Periapical Periodontitis
Effect of Corticosteroid Injection in Symptomatic Pulpitis Cases
This randomized clinical trial compared standard single-visit root canal treatment with adjunctive submucosal betamethasone and gentamicin in 100 patients with symptomatic irreversible pulpitis, assessing postoperative pain and…
- Trial name
- (SCIP) (NCT07704398)
- Testing
- Corticosteroid, Standard endodontic treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Infectious Disease, Fever
Validation of a Proteomic Signature and Assessment of Viremia in Children With Fever Without Source
The study is an observational blinded Validation study in pediatric patients below 3 years old with a diagnosis of Fever Without Source (FWS).
- Conditions
- Infectious Disease, Fever, Viremia
- Trial name
- NCT03224026
- Where
- Switzerland
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- MeMed Diagnostics Ltd.
Cardiovascular Diseases, Metabolic Syndrome X
Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome
The purpose of the study is to test higher versus lower doses of aspirin on markers of atherosclerosis in patients at risk of a first heart attack.
- Conditions
- Cardiovascular Diseases, Metabolic Syndrome X, Atherosclerosis
- Trial name
- PAD (NCT00272311)
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Florida Atlantic University
Systemic Inflammatory Response Syndrome, Sepsis
Alpha-1-acid Glycoprotein as a Biomarker of Developmental Diagnosing and Monitoring Effectiveness in Sepsis
To assess the potential value of alpha-1-acid glycoprotein (AGP) for early diagnosis and prognosis of patients with sepsis, and then compared with C-reactive protein (CRP), procalcitonin (PCT), white blood cell (WBC) counts…
- Trial name
- NCT01838525
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital