Clinical trials: Inflammatory Mediators
Chronic Obstructive Airway Disease, Healthy Volunteers
Regulation of the Release of Inflammatory Mediators From Blood Leukocytes
Chronic obstructive pulmonary disease (COPD for short) involves inflammation inside the air passages of the lungs. This inflammation might be partly responsible for the shortness of breath, cough and susceptibility to chest…
- Trial name
- NCT00180765
- Testing
- Up to 100ml blood will be taken by venupuncture.
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Sepsis
Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis
Aims of the study were to find vascular markers of inflammation and endothelial damage during the course of severe sepsis in septic patients and the effects of treatment with anti-inflammatory medication (such as Drotregocin alfa…
- Trial name
- NCT00222222
- Testing
- vein puncture
- Where
- Germany
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Healthy
Effect of Garlic on Inflammatory Mediators
This research will investigate the effect of garlic oil extract when added to daily diet on inflammatory mediators and blood clotting activation.
- Trial name
- NCT00275405
- Testing
- Garlic Oil Macerate
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Sepsis
Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis
During the past years many investigators have focused on the immunological changes in sepsis disease, and great attention has been paid to the development of practicable means of immunomonitoring.
- Trial name
- MaSep (NCT01535534)
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Psoriasis (PsO), Periodontal Disease
Evaluation of TNF-α, IL-17A, and YKL-40 in GCF and Serum of Psoriasis Patients and Healthy Controls
Background: Psoriasis is a chronic inflammatory skin disease that affects 2-3% of the global population and is linked to immune dysregulation and systemic inflammation.
- Trial name
- NCT06897722
- Testing
- TNF-α analysis in GCF, IL-17A analysis in GCF, YKL-40 analysis in GCF
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zhala Vatankha Sain
Irreversible Pulpitis
Effect of Conservative Root Canal Instrumentation on the Release of Inflammatory Mediators in Root Canal Treatments
The goal of this clinical trial is to evaluate the expression of inflammatory mediators in the crevicular fluid and periodontal ligament after one-visit root canal treatment of mandibular molars of patients with asymptomatic…
- Trial name
- NCT06237985
- Testing
- ProTaper Gold file system, OneShape file system, TruNatomy file system
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Asthma
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
Asthma is a heterogeneous disorder in which multiple potential inflammatory pathways contribute to airway obstruction. The biological basis for airway inflammation is the subject of intensive investigation.
- Trial name
- NCT00595491
- Testing
- Bronchoscopy, Segmental Allergen Challenge, and Broncheoalveolar Lavage
- Where
- United States
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Benjamin Medoff
Allergic Conjunctivitis
Effect of Olopatadine on Allergic Tear Mediators
The purpose of the research is to determine which inflammatory substances are involved in causing allergic symptoms in the eye. Allergic conjunctivitis is a common problem with symptoms of temporary redness, itching, tearing, and…
- Trial name
- NCT00609128
- Testing
- olopatadine
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Coronary Heart Disease
Adipose Tissue and Inflammation in Coronary Heart Disease
The aims of the present project are to study possible differences in inflammatory gene expression and protein secretion in various compartments of adipose tissue being exposed during open cardiac surgery in patients with coronary…
- Trial name
- ATICH (NCT02760914)
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Dry Eye
Effects of Topical Insulin on Levels of Tear Inflammatory Mediators
60 samples are take to determine the effects of topical insulin on tear inflammatory mediators interleukin 1a, interleukin 6 and matrix metalloprotenase 9 in diabetics with dry eye disease.
- Trial name
- NCT04877210
- Testing
- Topical Insulin
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre