Clinical trials: Inflammatory Response in Total Knee Arthroplasty
Other Acute Postoperative Pain, Systemic Inflammatory Response Syndrome
Systemic Inflammation Versus Acute Pain in Total Knee Arthroplasty (TKA)
In this study we evaluate if there is a correlation between acute pain and systemic inflammatory markers after total Knee Arthroplasty (TKA).
- Trial name
- NCT01322074
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Hvidovre University Hospital
Knee Osteoarthritis
An Artificial Intelligence-based Approach in Total Knee Arthroplasty: From Inflammatory Responses to Personalized Medicine
Goal: The goal of this interventional study is to understand how multimodal preoperative data can predict outcomes after Total Knee Arthroplasty (TKA) and improve personalized medicine practices.
- Trial name
- AI-TKA (NCT06634654)
- Testing
- Total Knee Arthroplasty, Multifaceted diagnostic assessments, Follow-ups
- Where
- Italy
- Volunteers
- 197 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Knee Osteoarthritis, Arthritis
Inflammatory Response Conventional Total Knee Replacement Versus Mako Total Knee Replacement
Total knee Arthroplasty (TKA) is a highly effective treatment for knee osteoarthritis. Mid- to long-term follow-up studies have shown good clinical outcomes following TKA; despite these results, there is a high incidence of…
- Conditions
- Knee Osteoarthritis, Arthritis, Surgery
- Trial name
- NCT04192006
- Testing
- Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
Postoperative Inflammatory Response
Steroids in Bilateral Total Knee Replacement
Inflammation related to cytokine release is known to occur with surgery. The cytokine IL6, a major marker of inflammation is known to increase during total joint replacement surgery.
- Trial name
- NCT01399268
- Testing
- Hydrocortisone, Saline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Inflammation, Magnesium Deficiency
Systemic Inflammatory Response: Thiamine and Magnesium Status (Sir TaM Study)
We wish to determine to what extent magnesium, thiamine and transketolase activity are affected by the Systemic Inflammatory Response (SIR).
- Conditions
- Inflammation, Magnesium Deficiency, Iron-deficiency, Thiamine Deficiency
- Trial name
- SirTaM (NCT03554668)
- Testing
- Blood draw
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- Glasgow Royal Infirmary
Inflammatory Response in Total Knee Arthroplasty
Spinal Versus General Anesthesia and Inflammatory Response Measured by Delta Neutrophil Index in Total Knee Arthroplasty: An Observational Study
This study aims to compare the effects of spinal versus general anesthesia on the inflammatory response measured by Delta Neutrophil Index (DNI) in patients undergoing total knee arthroplasty.
- Trial name
- DNA-TKA (NCT07214558)
- Testing
- Routine Clinical Anesthesia Practice
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Spinal Aneshtesia, General Anesthetic
Effects of Anesthesia Type on Inflammatory Response
In total knee arthroplasty, surgical and anesthetic procedures can lead to a significant increase in systemic inflammation. This procedure is frequently performed under either general or spinal anesthesia.
- Conditions
- Spinal Aneshtesia, General Anesthetic, Inflammation, Neutrophils
- Trial name
- NCT06984315
- Testing
- The effects of the groups on perioperative inflammation changes were compared.
- Where
- Turkey (Türkiye)
- Volunteers
- 849 people
- Sponsor
- Tokat Gaziosmanpasa University