Clinical trials: Influenza Virus Infection
Influenza, Human
A Study About Modified RNA Vaccines Against Influenza in Healthy Adults
The purpose of this study is to learn if modified RNA (modRNA) vaccines for the prevention of influenza are: safe; and how these vaccines produce an immune response in generally healthy adults.
- Trial name
- NCT06436703
- Testing
- Influenza ModRNA Vaccine, Quadrivalent Influenza Vaccine (QIV)
- Where
- 32 sites in United States
- Volunteers
- 1,202 people, healthy volunteers welcome
- Sponsor
- Pfizer
Influenza
Chinese Medicinal Herbs Treatment on Novel Influenza A (H1N1)Pneumonia: Multi-centre, Prospective, Randomized Controlled Study
The purpose of the study is to determine whether the combination treatment of Chinese medicinal herbs and oseltamivir is more effective than single oseltamivir in treating novel influenza A (H1N1) pneumonia.
- Trial name
- NCT00936013
- Testing
- oseltamivir, oseltamivir and chinese medicinal herbs
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Capital Medical University
2009 H1N1 Influenza
Effect of Age and Prior Immunity on Response to H1N1 Vaccines in Children
A total of 51 children between the ages of 4 and 9 will be randomized to receive a two dose schedule of either licensed live attenuated A/California/07/09 influenza vaccine (LAIV) or licensed inactivated A/California/07/09…
- Trial name
- H1N1Children (NCT01097941)
- Testing
- Live Attenuated H1N1 Influenza Vaccine, Influenza A (H1N1) 2009 Monovalent Vaccine, Influenza A (H1N1) 2009 Monovalent Vaccine/ Influenza A (H1N1) Monovalent Vaccine Live
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Influenza, Human
Phase 3 Pivotal Trial of NanoFlu™ in Older Adults
A Phase 3, randomized, observer-blinded, active-controlled trial to evaluate the immunogenicity and safety of a recombinant quadrivalent nanoparticle influenza vaccine with Matrix-M1 adjuvant (NanoFlu) compared with a licensed…
- Trial name
- NCT04120194
- Testing
- NanoFlu, Fluzone Quadrivalent
- Where
- 19 sites in United States
- Volunteers
- 2,654 people, healthy volunteers welcome
- Sponsor
- Novavax
Influenza, Human, Acute Respiratory Infection
Efficacy and Safety Study of Ingavirin® to Treat Influenza and Acute Respiratory Viral Infections in Patients 13-17 y.o.
The purpose of this study is to determine whether Ingavirin ® dosed 60 mg daily is effective and safe in the treatment of influenza and other acute respiratory viral infections in 13-17 years old patients.
- Conditions
- Influenza, Human, Acute Respiratory Infection, Viral Infection, Common Cold
- Trial name
- NCT03206346
- Testing
- Ingavirin
- Where
- 5 sites in Russia
- Volunteers
- 161 people
- Sponsor
- Valenta Pharm JSC
Influenza, COVID-19
Patient-Centered Practical Vaccine Talk For Busy Clinicians
The goal of this study is to assess the effect of an educational intervention for primary care providers (PCPs) on influenza and COVID-19 vaccine uptake among their adult patients through a pragmatic, cluster randomized trial in…
- Trial name
- PCP-VAX (NCT07651761)
- Testing
- Provider communication training
- Where
- United States
- Volunteers
- 24,500 people
- Sponsor
- University of Massachusetts, Worcester
Rheumatoid Arthritis
Effectiveness of SMS Reminders on Influenza Vaccination Coverage in Patients With RA in the ART Registry
Biotherapies have significantly improved the prognosis of rheumatoid arthritis (RA), particularly anti-TNF. However, these molecules are associated with a well-demonstrated increase in infectious risk, including an over-risk of…
- Trial name
- NCT05220423
- Testing
- sms and emails reminders, No reminders
- Where
- France
- Volunteers
- 446 people
- Sponsor
- Societe Francaise de Rhumatologie
Influenza
Study to Assess the Efficacy and Safety of GP681 Versus Placebo for Postexposure Prophylaxis Against Influenza
Index patients who are infected with influenza virus (Q-PCR positive) can be treated with anti-influenza drugs if their influenza symptoms onset was within 48 hours of screening.
- Trial name
- NCT06574503
- Testing
- GP681 40mg, GP681 Simulant
- Where
- China
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Aspergillosis, Candidemia
UARK 2009-99 A Non-interventional Observational Study of Infectious Complications in Cancer Patients
OBSERVATIONAL STUDY OF INFECTIOUS COMPLICATIONS IN CANCER PATIENTS
- Conditions
- Aspergillosis, Candidemia, C. Difficile
- Trial name
- NCT01622595
- Where
- United States
- Sponsor
- University of Arkansas
Respiratory Tract Diseases, Influenza (Pandemic)
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of hospitalised…
- Conditions
- Respiratory Tract Diseases, Influenza (Pandemic), Influenza, Community Acquired Pneumonia
- Trial name
- REMAP-CAP (NCT02735707)
- Testing
- Ceftriaxone + Macrolide, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam + Macrolide
- Where
- 408 sites in United States, Australia and 27 more
- Volunteers
- 20,000 people
- Sponsor
- UMC Utrecht
Influenza
Safety and Immunogenicity of a Monovalent Inactivated Influenza H3N2 Variant (H3N2v) Vaccine in Pediatric Populations
This is a Phase II open-label study in approximately 240, and up to 400, healthy males and non-pregnant females, aged 6 months to 17 years.
- Trial name
- NCT02100436
- Testing
- Influenza Virus Vaccine, Monovalent A/H3N2v A/Minnesota/11/2010 NYMC X-203
- Where
- 8 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Influenza
A Trial on the Efficacy, Safety and Immunogenicity of Live-Attenuated Influenza Vaccine (LAIV)
This study is a Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase Ⅲ Trial to evaluate the efficacy, safety and immunogenicity of a single dose of Live-Attenuated influenza Vaccine(LAIV) among healthy children and…
- Trial name
- NCT02964065
- Testing
- Live-Attenuated influenza Vaccine(LAIV)
- Where
- 3 sites in China
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Changchun BCHT Biotechnology Co.
Influenza
CS-8958 Single Inhaled Dose in Elderly
The purpose of this study is to test the safety and tolerability of an investigational inhaled flu medication, CS-8958. Study participants will include 38 elderly males and females, age 65 and older.
- Trial name
- NCT00657111
- Testing
- CS-8958 formulated as dry powder
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Biota Scientific Management Pty Ltd
Influenza
Clinical Efficacy of Trivalent Live-Attenuated Influenza Vaccine (LAIV) Among Children in Senegal
This study will provide the Senegal Ministry of Health with data on the clinical efficacy of the Live-Attenuated Influenza Vaccine (LAIV). This data will inform future policy considerations for influenza vaccine.
- Trial name
- NCT01854632
- Testing
- SIIL Live Attenuated Influenza Vaccine
- Where
- Senegal
- Volunteers
- 1,761 people, healthy volunteers welcome
- Sponsor
- PATH
Influenza
Prospective Study of AI H5N1 in China
The purpose of this study is to see if people in China who have contact with someone infected with bird flu (H5N1) become infected themselves without necessarily getting sick.
- Trial name
- NCT00428493
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Influenza, Human
A Study to Assess the Immune Response and Safety of a Vaccine Against Influenza in Adults 18 Years of Age and Older
"The purpose of this study is to assess the reactogenicity, safety and immune response of GlaxoSmithKlines (GSK) messenger RNA (mRNA)-based multivalent seasonal influenza vaccine candidates administered in healthy younger and…
- Trial name
- NCT07121192
- Testing
- Flu mRNA (Formulation A), Flu mRNA (Formulation B), Comparator 1
- Where
- 22 sites in United States
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza Vaccination
Incentives for Influenza Vaccination
In this work, we are assessing the impact of messaging with or without a $50 financial incentive on influenza vaccination rates in a county health system.
- Trial name
- NCT06300242
- Testing
- Reminders, Financial Incentive
- Where
- United States
- Volunteers
- 69,972 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Influenza, COVID-19
Commercially Available Cannabis Products for Immune Support
This study will be a prospective observation of the use of commercially available hemp and cannabis products marketed for immune support.
- Conditions
- Influenza, COVID-19, Common Cold
- Trial name
- NCT05944705
- Testing
- Immune Support Supplement
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Center For Interventional Pain and Spine
Influenza
Vitamin A and Maternal-infant Flu Vaccine Response
Influenza viral infection can cause serious illness among young infants 0-6 months of age. However, inactivated influenza vaccine is not recommended for this age group but pregnant women can be vaccinated during 2nd - 3rd…
- Trial name
- NCT00817661
- Testing
- Vitamin A
- Where
- Bangladesh
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Influenza
Comparative Clinical Trial of Efficacy and Safety of Ergoferon Versus Oseltamivir in Treatment of Influenza
The purpose of this study is: to assess the efficacy of Ergoferon in treatment of influenza; to assess the safety of Ergoferon in treatment of influenza; to compare the efficacy of Ergoferon and Oseltamivir for treatment of…
- Trial name
- NCT01850446
- Testing
- Ergoferon, Oseltamivir
- Where
- 7 sites in Russia
- Volunteers
- 184 people
- Sponsor
- Materia Medica Holding
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