Clinical trials: Information Disclosure
HIV Infections
Novel Internet-Based Interventions to Reduce Sexual Risk Among Men Who Have Sex With Men
The purpose of this study is to develop and test the efficacy of online HIV risk reduction interventions among men who have sex with men.
- Trial name
- 5Part (NCT00649701)
- Testing
- Standard Text-Based Prevention Web Page, The Morning After, Talking About HIV
- Where
- United States
- Volunteers
- 3,097 people, healthy volunteers welcome
- Sponsor
- Public Health Solutions
HIV, PMTCT
Study to Determine Impact of Feeding Buddies on Adherence to WHO PMTCT Guidelines in South Africa
The 2010 revised WHO recommendations to provide antiretroviral (ARV) prophylaxis or treatment to mothers or infants during the breastfeeding period indicate a paradigm shift in prevention of mother-to-child transmission (PMTCT)…
- Trial name
- NCT02162498
- Testing
- Feeding buddies
- Where
- South Africa
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- PATH
Healthy
A Trial on the Effect of Emotional Disclosure of Traumatic Life Events on Physical Health
This is a randomized, controlled trial on the effect of emotional disclosure of traumatic life events on physical health. The hypothesis is that expression of emotions could possibly improve physical health.
- Trial name
- NCT00896844
- Testing
- emotional disclosure
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham
Literacy, Information Disclosure
ECA vs E-Document Explanation
This study will investigate how consent forms and other health care documents are explained to patients. The findings will be used to create a computer program that can successfully explain consent and other health-related forms…
- Trial name
- NCT03381911
- Testing
- Embodied Conversational Agent
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Education
Transition From Research to Disclosure in Human Genetics
The goal of this study is to design a means of providing research families, from diverse geographical locations, the chance to receive genetic testing after having been educated by video, and meetings or telephone conversations…
- Trial name
- NCT00505466
- Testing
- Genetic Counseling
- Where
- United States
- Volunteers
- 577 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cardiovascular Diseases
Personalised HeartCare: Poligenic Risk Scores Disclosure for Cardiovascular Prevention
The goal of this clinical trial is to evaluate whether the disclosure of Polygenic Risk Scores (PRS) combined with personalized coaching on risk factors can lead to significant improvements in lifestyle behaviors among staff…
- Trial name
- PHC (NCT06888466)
- Testing
- The result of the Polygenic Risk Score will be communicated to the patient with the aim of encouraging a change in behavior
- Where
- Italy
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Bereavement
Bereaved Young Adults Study
Bereaved adolescents and emerging adults are at risk for developing psychological disorders and complicated grief. Clinical grief interventions and conventional wisdom reflect an implicit assumption that sharing and expressing…
- Trial name
- NCT05352243
- Testing
- Expressive Disclosure, Expressive Helping, Fact-Writing
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Trust
Do Patients Perceive Surgeons Who Provide Personal Information as More Trustworthy and Empathetic?
Prior studies have shown that patient trust in their physician is associated with better health outcomes and lower levels of emotional distress.
- Trial name
- NCT04213625
- Testing
- Surgeon Personal Background
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Hiv
Exploring a Digital HIV Onward Disclosure Intervention, in People Living With HIV of Sub-Saharan African Ethnicity.
Research has shown that people living with HIV struggle to disclose their HIV status to others, (a process known as self-disclosure or onward disclosure) due to associated challenges, including fear of discrimination from others.
- Trial name
- NCT05804968
- Testing
- Digital HIV Self Disclosure Intervention
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
Informed Consent, Comprehension
AI-Driven Consent Simplification Study
The overarching goal of this pilot is to explore how generative artificial intelligence (genAI) can be used to improve the accessibility and understandability of informed consent materials in clinical research.
- Conditions
- Informed Consent, Comprehension, Communication, Disclosure
- Trial name
- ACCESS (NCT07303517)
- Testing
- Original ICF, AI Simplified ICF, Podcast - Original ICF
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV
Assessing Strategies for Increasing Male Involvement in Malawi's Antenatal Program
In sub-Saharan Africa, engaging men in HIV prevention, care, and treatment has proven challenging. Along all steps of the HIV care-seeking cascade, men exhibit worse care-seeking behaviors than women.
- Trial name
- NCT02139176
- Testing
- contract referral, patient referral
- Where
- Malawi
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
COVID19
Let It Out (LIO) and COVID19: Testing an Online Emotional Disclosure-based Intervention During the COVID19 Pandemic
A randomised controlled trial designed to test whether an online expressive writing intervention (LIO-C) can reduce distress for English-speaking adults during the global COVID19 pandemic.
- Trial name
- LIO-C (NCT04386668)
- Testing
- Let It Out (LIO)-C, Neutral writing control
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University College, London
Lewy Body Disease
Alpha-synuclein Education and Disclosure in Individuals With Preclinical and Symptomatic Lewy Body Disease
The goal of the study is to assess if learning one's Lewy Body Dementia (LBD) biomarker test result impacts longitudinal psychosocial and behavioral responses and to identify factors that moderate and mediate these outcomes.
- Trial name
- NCT07646652
- Testing
- LBD Biomarker Education and Disclosure
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Patient Doctor Trust
Disclosure of Industry Payments to Physicians and the Patient-Doctor Relationship
Pharmaceutical and medical device manufacturers work closely with doctors and hospitals, and the companies often pay large sums for consulting and advising services.
- Trial name
- NCT02179632
- Testing
- Exposure to disclosure website
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Disclosure of Protective Message
The Effect of a Protective Message on Critical Evaluation of Fake News
Background: Disinformation has become an increasing societal concern, especially due to the speed that news is shared in the current digital era.
- Trial name
- NCT05030883
- Testing
- Source of news
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tilburg University
Error Disclosure, Diagnoses Disease
A Priori Diagnosis and Diagnostic Errors
This is a prospective randomized single-blind simulator-based trial. 156 4th year medical students were randomised to receive one of three different suspected diagnoses of a pre-treating physician (no diagnosis, myocardial…
- Conditions
- Error Disclosure, Diagnoses Disease, Simulation of Physical Illness
- Trial name
- NCT04659265
- Testing
- Suspected diagnosis of a pre-treating physician
- Where
- Switzerland
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Fertility Issues, Disclosure
Feasibility Trial of the TELL Tool Intervention
A radical paradigm shift is taking place where technology, notably the explosion in easy accessible direct-to-consumer genetic testing (e.g., 23andMe) and a high consumer interest in genealogy (e.g., Ancestry.com), has hijacked…
- Conditions
- Fertility Issues, Disclosure, Parenting
- Trial name
- NCT04841967
- Testing
- TELL Tool Intervention, eBook Attention Control
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
HIV Infections, Sexually Transmitted Infections (Not HIV or Hepatitis)
Developing an HIV Disclosure Intervention for Men in Uganda
The goal of this clinical trial is to test an HIV disclosure intervention that the investigators are developing focused on men living with HIV in Uganda.
- Trial name
- DASH (NCT05771519)
- Testing
- HIV disclosure intervention
- Where
- Uganda
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Mental Illness, Behavior Disorders
Up To Me: Erasing the Stigma of Mental Illness on College Campuses
This is a three-lesson, disclosure-based stigma reduction program meant to reduce barriers to community living and participation for college students with psychiatric disabilities.
- Conditions
- Mental Illness, Behavior Disorders, Severe Mental Illness, Psychiatric Diagnosis
- Trial name
- NCT05784818
- Testing
- Up To Me Intervention + No Booster, Up To Me Intervention + Booster
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Endodontic Diseases, Clinical Communication
Generative AI-Based Immersive Training for Endodontic Risk Disclosure and Informed Consent Among Dental Students
The objective of this prospective, parallel-group, 1:1 randomized controlled trial is to evaluate the effectiveness of a generative artificial intelligence (AI)-based immersive training program, utilizing the Gemini platform, in…
- Conditions
- Endodontic Diseases, Clinical Communication, Informed Consent
- Trial name
- GAI-ENDORDIC (NCT07731867)
- Testing
- Generative AI-Based Immersive Training, Conventional Case-Based Learning
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine