Clinical trials: Informed Decision-making
Lung Neoplasms
Development and Feasibility Testing of a Lung Cancer Screening Decision Aid
This study evaluates the feasibility and acceptability of LuCaS Choices, a web-based decision aid designed to facilitate informed decision making about participation in lung cancer screening among individuals at high risk of lung…
- Trial name
- LuCaS-DA (NCT02790866)
- Testing
- LuCaS Decision Aid, NCI Website
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jamie Studts
Colorectal Cancer Screening
ICIBS Trial - Improving Patient Information About Bowel Cancer Screening - a Decision Aid Trial
This project has been completed and consisted of a randomised trial of six tailored decision aids giving patients evidence-based information about faecal occult blood test screening for bowel cancer.
- Trial name
- NCT00148226
- Testing
- Decision Aid
- Where
- Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sydney
Adolescents
Parental Permission and Adolescent Assent and Decision-Making in Clinical Research
This study will evaluate how adolescents enrolled in clinical research and their parents: Understood the study information presented before they agreed to participate Made decisions about enrolling in the study Experienced the…
- Trial name
- NCT00571311
- Where
- United States
- Volunteers
- 356 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Prematurity, Framing
Framing and Decision Making in Neonatology
The purpose of this study is to study how people make decisions regarding delivery room management for infants born extremely premature when survival and long term outcomes are uncertain.
- Conditions
- Prematurity, Framing, Perinatal Decision Making
- Trial name
- NCT01421238
- Testing
- Survey
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Columbia University
Pregnancy - Prenatal Testing
Informed Choice Regarding Invasive Prenatal Testing
This study will compare the effectiveness of two interventions to help women make informed choices about whether or not to undergo an invasive procedure (amniocentesis or chorionic villus sampling) for prenatal testing.
- Trial name
- NCT00514553
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Cancer, Health Literacy
Improving Cancer Patients' Insurance Choices
The goal of this research study is to find out if a decision aid (DA) created by investigators, I Can PIC, is effective in helping cancer patients make decisions about their health insurance.
- Conditions
- Cancer, Health Literacy, Health Insurance, Health Services Accessibility
- Trial name
- I Can PIC (NCT03592433)
- Testing
- I Can PIC
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Educational Problems
Improving Informed Decision Making for Cancer Clinical Trial Participation
The goal of this study is to develop and pilot test a multi-communication approach to improve informed decision-making about cancer Clinical Trials (CTs) participation by increasing awareness of CTs and Mays Cancer Center (MCC)…
- Trial name
- NCT03820687
- Testing
- Clinical Trial Educational Video, Clinical Trial Fact Sheet, Low literacy booklet
- Where
- United States
- Volunteers
- 581 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Human Immunodeficiency Virus, Human Immunodeficiency Virus Transmission
The OPENS Trial: Offering Women PrEP (Aim 2)
To address the significant barriers to pre-exposure prophylaxis (PrEP) implementation for cisgender women and address racial inequities in HIV prevention in the United States (US), a novel approach that accounts for multilevel…
- Conditions
- Human Immunodeficiency Virus, Human Immunodeficiency Virus Transmission, Sexually Transmitted Diseases
- Trial name
- NCT05619497
- Testing
- Clinic-wide Trainings, Clinic-wide Trainings and HIV Prevention Decision Support Tool (DST), Standard Care with the HIV Prevention Decision Support Tool (DST)
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Kidney Diseases, Apolipoprotein L1
APOL1 Genetic Testing Program for Living Donors
Living donor (LD) kidney transplantation is the optimal treatment for patients with end-stage kidney disease (ESKD). However, LDs take on a higher risk of future ESKD themselves.
- Conditions
- Chronic Kidney Diseases, Apolipoprotein L1, Kidney Transplantation
- Trial name
- NCT04910867
- Testing
- Components of Genetic Counseling, APOL1 genetic testing, EHR integration
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- Northwestern University
Vestibular Hypofunction
Making INformed Decisions in Gaze and Postural Stability: A Pilot Feasibility Study
The proposed research is relevant to vestibular science and the general public because age-related vestibular hypofunction is a major contributor to poor balance, falls, and other adverse health outcomes.
- Trial name
- MINDGAPS (NCT05391932)
- Testing
- MINDGAPS
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Montana
Prenatal Disorder
Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes
The goal of this study is to ensure that pregnant patients have the resources and support needed to access Prenatal Screening \& Diagnostic Testing (PS\&D) in an informed and evidence-based fashion by developing an innovative…
- Trial name
- OPUS (NCT06382636)
- Testing
- Standard Care, Obstetric Prenatal Genetic Testing Engagement Solution (OPUS) AI Chatbot
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- The Cleveland Clinic
Prostate Cancer, Metastatic Prostate Cancer
MENCORE-2: Audio Recordings to Improve Decision-making in Advanced Prostate Cancer
This is a single-arm hybrid implementation trial of men with metastatic castrate-resistant prostate cancer (mCRPC) involving a patient-administered mobile app for consultation audio recordings.
- Conditions
- Prostate Cancer, Metastatic Prostate Cancer, Metastatic Castration-resistant Prostate Cancer
- Trial name
- NCT05127850
- Testing
- Consultation audio recording app
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of California, San Francisco
Colorectal Cancer, Shared Decision Making
Preoperative 3D Models and Shared Decision-making
The objectives of this study will be to quantify, using validated scales, the effects of 3D-printed models on shared decision-making and patient anxiety during the pre-operative consent and education process.
- Conditions
- Colorectal Cancer, Shared Decision Making, Anxiety, Informed Consent
- Trial name
- NCT06625008
- Testing
- 3D-printed model
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Vanderbilt University Medical Center
Alzheimer Disease, Neurodegenerative Diseases
Decision-making, Ethical Consent, and Interactive Dialogue in Ongoing Neurocognitive Decline - DECISION
DECISION Study - Summary Title: Decision-making, Ethical Consent, and Interactive Dialogue in Ongoing Neurocognitive Decline The DECISION study aims to develop and validate a simplified yet robust tool for assessing the capacity…
- Trial name
- DECISION (NCT07514520)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Colorectal Cancer
Use and Decision-making About Colorectal Cancer Screening Among Hispanic Men and Women
During this first year, the researchers have worked toward identifying factors influencing initiation of colorectal cancer screening among Hispanic men and women aged 50 and older and developing an intervention plan using…
- Trial name
- NCT00136227
- Testing
- small media intervention using video, flip chart, and pamphlets and a tailored interactive multimedia intervention
- Where
- United States
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Vestibular Hypofunction
Improving Psychological and Vestibular Health: MINDGAPS
The purpose of this study is twofold: 1) Develop norms for measures of inner ear function and psychological health, and 2) Examine the feasibility of using the MINDGAPS system (a remote monitoring system) to track progress during…
- Trial name
- MINDGAPS (NCT05986279)
- Testing
- Rehab
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Montana
Localized Prostate Cancer
Treatment Decision Making in Early-Stage Prostate Cancer
We plan to test the effectiveness of a recently developed computer-based program that is designed to improve patient knowledge about prostate cancer treatments.
- Trial name
- NCT00196781
- Testing
- CD-ROM-based prostate cancer treatment education, CD-ROM-based prostate ca treatment education+decision tools
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Georgetown University
Prostate Cancer, Shared Decision Making
RCT of NLP-Based Feedback for Improving SDM in Men With Localized Prostate Cancer
The purpose of the research is to assess the impact of a natural language processing + artificial intelligence (NLP+AI)-based risk communication feedback system to improve quality of risk communication of key tradeoffs during…
- Conditions
- Prostate Cancer, Shared Decision Making, Risk Communication
- Trial name
- NLP RCT (NCT06856694)
- Testing
- NLP+AI Report
- Where
- United States
- Volunteers
- 283 people
- Sponsor
- Cedars-Sinai Medical Center
Prostate Carcinoma
Informed Decision Making Intervention in Screening for Prostate Cancer of Predominantly African American Participants in a Community Outreach Program
This clinical trial studies an informed decision making intervention of screening for prostate cancer in predominantly African American participants.
- Trial name
- NCT02419846
- Testing
- Educational Intervention, digital rectal examination, Pre-test administration
- Where
- United States
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Sickle Cell Disease
Motivations, Expectations, and Decision-making of Sickle Cell Patients in Clinical Research
Background: Sickle cell disease is an inherited blood disorder. People with this disease have a problem with their hemoglobin. That is a protein in red blood cells that carries oxygen in the body.
- Trial name
- NCT03709303
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- National Institutes of Health Clinical Center (CC)