Clinical trials: Inguinal Hernioplasty
Hernia, Inguinal, Inguinal Hernia, Direct
Study of Laparoscopic Inguinal Hernia Repair
Although mesh fixation has been associated to an increased incidence of nerve injury and involves increased operative costs, many surgeons feel that fixation is necessary to reduce the risk of hernia recurrence.
- Conditions
- Hernia, Inguinal, Inguinal Hernia, Direct, Inguinal Hernia, Indirect, Hernia, Femoral
- Trial name
- NCT02920307
- Testing
- TEP without fixation, TEP with fixation, TAPP without fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Medical Park Gaziantep Hospital
Inguinal Herniorrhaphy, Orchiopexy
Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine
Caudal epidural analgesia (caudal block) is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et…
- Trial name
- NCT00616577
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Loma Linda University
Hernia, Inguinal, Postoperative Complications
Prospective Study Investigating Aspirin and Intraoperative Blood Loss and Complications Following Inguinal Hernia Repair
The purpose of this study is to determine whether aspirin taken in the perioperative period will increase the blood loss associated with open inguinal hernia repairs.
- Conditions
- Hernia, Inguinal, Postoperative Complications, Postoperative Hemorrhage
- Trial name
- NCT02084615
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Jesse Brown VA Medical Center
Dexmedetomidine, Ketofol
Dexmedetomidine vs Ketofol on Delirium in Children Undergoing Congenital Inguinal Hernia Repair
The aim of this study is to compare the effect of dexmedetomidine versus ketofol on the incidence of the emergence delirium in children undergoing congenital inguinal hernia repair.
- Conditions
- Dexmedetomidine, Ketofol, Delirium, Hernia
- Trial name
- NCT05786833
- Testing
- Dexmedetomedine, Ketofol, isotonic saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Seroma, Hernia, Inguinal
Use of Diathermy Versus Blunt Dissection in TEP for Inguinal Hernia
There is a long debate whether monopoloar or blunt dissection should be adopted in TEP to minimise the chance of seroma formation.
- Trial name
- NCT03665883
- Testing
- Monopolar energy, Blunt dissection
- Where
- China
- Volunteers
- 103 people
- Sponsor
- The University of Hong Kong
Hernia, Inguinal
Non-Mesh Versus Mesh Method for Inguinal Hernia Repair
The study aims at establishing the effectiveness of the non-mesh (Desarda) technique for the treatment of primary inguinal hernias at Mulago Hospital in Uganda.
- Trial name
- IHR (NCT00941941)
- Testing
- Non-mesh Hernia Repair, Mesh Hernia Repair
- Where
- Uganda
- Volunteers
- 98 people
- Sponsor
- Makerere University
Inguinal Hernia, Femoral Hernia
The Importance of Preserving the Round Ligament in the Repair of Inguinal Hernias in Women
The aim of this study is to evaluate the impact of preserving or not preserving the round ligament during laparoscopic Trans Abdominal Pre-Peritoneal (TAPP) hernia repair on postoperative outcomes in female patients.
- Conditions
- Inguinal Hernia, Femoral Hernia, Obturator Hernia
- Trial name
- NCT06786702
- Testing
- Laparoscopic TAPP (Trans Abdominal Pre-Peritoneal) hernia repair: Round Ligament Preservation, Laparoscopic TAPP (Trans Abdominal Pre-Peritoneal) hernia repair: Round Ligament Cutting
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Muhammet Mustafa Vural
Analgesia
Study of Post-Herniorrhaphy Non-opioid MMA Regimens
This is a Phase 3b, open-label study to assess postoperative opioid use in subjects undergoing unilateral open inguinal herniorrhaphy with intraoperative administration of HTX-011 and a postoperative non-opioid multimodal…
- Trial name
- NCT03907176
- Testing
- HTX-011, Luer lock applicator, Ibuprofen
- Where
- 30 sites in United States
- Volunteers
- 209 people
- Sponsor
- Heron Therapeutics
Inguinal Hernia
Biomechanically Compatible,Minimally Invasive Technique for Recurrence Free Groin Hernia Repair
"A bio-mechanically compatible, minimally invasive technique for recurrence-free groin hernia repair by implantation of Tensiflex mesh prosthesis for the enhancement of the tissue tensile strength of the fascia transversalis."
- Trial name
- NCT04764760
- Testing
- Wing shaped Tensiflex prosthesis
- Where
- United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- St. Joseph Mercy Oakland Hospital
Pain, Beta-endorphin
Double-blind, Randomized Controlled Study to Assess the Analgesic Effect of 2 g of Magnesium Dipyrone (Metamizol) and Changes in Plasma Beta-endorphin Immunoreactivity Values in Patients Undergoing Elective Inguinal Herniorrhaphy Under Epidural Anesthesia.
A double-blind, randomized controlled study is designed to assess the analgesic effect of a single intravenous dose of 2 g of magnesium dipyrone (metamizol) and whether the administration of the active drug will be associated…
- Conditions
- Pain, Beta-endorphin, Dipyrone, Hernia Surgery
- Trial name
- NCT04595877
- Testing
- Dipyrone administration, Pain assessment, beta-endorphin immunoreactivity
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Antonio Martín Duce
Inguinal Hernia
Perioperative Rehab for Inguinal Hernia Repair
Despite how common inguinal hernia repair (IHR) surgery is, there is little research on how best to prepare people for this operation.
- Trial name
- NCT07680777
- Testing
- Rehabilitation
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- University of Alberta
Hernia, Inguinal, Hernia, Inguinal, Direct
Evaluation of Clinical Outcomes in Robotic-Assisted Inguinal Hernia Repair
This multi-center, retrospective data collection study will evaluate the feasibility, safety and performance of the da Vinci® surgical system for patients who have undergone robotic-assisted inguinal hernia repair, as well as…
- Conditions
- Hernia, Inguinal, Hernia, Inguinal, Direct, Hernia, Inguinal, Indirect
- Trial name
- NCT02684448
- Testing
- Inguinal Hernia Repair
- Where
- 2 sites in United States
- Volunteers
- 1,258 people
- Sponsor
- Intuitive Surgical
Inguinal Hernia
Laparoscopic Hernia Defect Obliteration With ProFlor-E
This feasibility study highlights the features of the 3D dynamic responsive prosthesis ProFlor-E® for fixation free obliteration of inguinal hernia defect
- Trial name
- NCT04718298
- Testing
- ProFlor laparoscopic technique
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Cagliari
Inguinal Hernia Bilateral, Inguinal Hernia Unilateral
Watchful Waiting Versus Immediate Repair for Occult Contralateral Inguinal Hernias.
This study will compare two ways of managing a small, hidden hernia that can sometimes be found during minimally invasive surgery to repair a hernia on one side of the groin.
- Trial name
- WATCH IT (NCT07461558)
- Testing
- surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, Watchful waiting with supportive care
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- Northwestern University
Recurrent Inguinal Hernia
Recurrent Inguinal Hernia Treatment - Lichtenstein Versus Laparoscopic Totally Extraperitoneal Preperitoneal Hernioplasty
The study aims at detecting possible differences between an open (Lichtenstein) and a video-assisted (TEP) technique in treating recurrent inguinal hernia.
- Trial name
- NCT00642200
- Testing
- Lichtenstein hernioplasty, Laparoscopic TEP
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- North Karelia Central Hospital
Indirect Inguinal Hernia
Study of Histological Findings of the Internal Inguinal Ring in Patients With Indirect Inguinal Hernia
The histology of the internal inguinal ring in patients with indirect hernia submitted to elective surgery was studied. In contrast with recently published studies, the investigators believe that histological findings of the…
- Trial name
- NCT01211067
- Testing
- Lichtenstein hernioplasty
- Where
- 2 sites in Chile
- Volunteers
- 72 people
- Sponsor
- Cirujanos la Serena
Inguinal Hernia
Glubran Mesh Fixation in Lichtenstein Hernioplasty
The purpose of the study is to investigate whether chronic postoperative pain is less frequent and quality of life better when inguinal mesh is fixed by using tissue glue compared to conventional sutures in inguinal hernioplasty.
- Trial name
- Cyanoacr (NCT00659542)
- Testing
- cyanoacrylate glue
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Kuopio University Hospital
Inguinal Hernia
The Effect of Dexamethasone on Rebound Pain in Patients Receiving Ilioinguinal and Iliohypogastric Nerve Block
Rebound pain is a newly defined phenomenon, observed within the first 24 hours after the operation. Open inguinal hernia repair is a common surgical procedure that can be associated with pain of the either acute or chronic…
- Trial name
- NCT05172908
- Testing
- Dexamethasone, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karaman Training and Research Hospital
Hernia, Inguinal
Effects of Using Divided Mesh and Using a Non Divided Mesh on Testicular Blood Flow and Volume in Laparoscopic Hernia Repair
Laparoscopic inguinal hernia repair techniques has been compared with the open techniques in several studies. However, no one studied about the different uses of the same type of mesh on the same surgical technique, and effects…
- Trial name
- NCT03421925
- Testing
- Laparoscopic totally extraperitoneal procedure for inguinal hernia
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Okan University
Hernia, Inguinal, Robotic Surgical Procedures
Robotic vs. Conventional Minimal-invasive Inguinal Hernia Repair
Minimal invasive techniques have become a well established approach for inguinal hernia repair over the last decade in developed countries.
- Trial name
- ROGER-RCT (NCT05216276)
- Testing
- TEP, rTAPP
- Where
- Switzerland
- Volunteers
- 182 people
- Sponsor
- University Hospital, Basel, Switzerland