Clinical trials: Inguinal Hernioplasty
Hernia, Inguinal
Comparative Study of Safety and Efficacy of Heavyweight and Partially Absorbable Mesh in Inguinal Hernia Repair
Proflex® Mesh (partially absorbable mesh, Korea) and Marlex® Mesh (heavyweight mesh) will be used for inguinal hernia repair to compare the safety and efficacy (pain score, quality of life)of two devices at 3 months follow-up.
- Trial name
- NCT01877122
- Testing
- Proflex® Mesh Mesh implantation, Marlex® Mesh Implant
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samyang Biopharmaceuticals Corporation
Inguinal Hernia, Laparoscopic Surgery
Uterine Round Ligament Preservation Vs Resection in Laparoscopic Inguinal Hernia Repair in Women：A Multicenter,Stratified Randomized Controlled Trial
This study aims to compare the clinical effects of uterine round ligament preservation versus resection in laparoscopic inguinal hernia repair in women.The primary outcomes included Time required for patient surgery.The secondary…
- Conditions
- Inguinal Hernia, Laparoscopic Surgery, Randomized Controlled Trial
- Trial name
- NCT06885788
- Testing
- To remove the uterine uterine ligament
- Where
- China
- Volunteers
- 466 people
- Sponsor
- Nanchong Central Hospital
Dexmedetomidine, Ketofol
Dexmedetomidine vs Ketofol on Delirium in Children Undergoing Congenital Inguinal Hernia Repair
The aim of this study is to compare the effect of dexmedetomidine versus ketofol on the incidence of the emergence delirium in children undergoing congenital inguinal hernia repair.
- Conditions
- Dexmedetomidine, Ketofol, Delirium, Hernia
- Trial name
- NCT05786833
- Testing
- Dexmedetomedine, Ketofol, isotonic saline 0.9%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Inguinal Hernia
Comparison of Patient Perceived Pain and Satisfaction Between Lightweight and Heavyweight Mesh for Laparoscopic Inguinal Hernia Repair
This study will be comparing the patients overall satisfaction of two different meshes used in laparoscopic inguinal hernia repairs.
- Trial name
- NCT01638221
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ascension Health
Inguinal Hernia, Femoral Hernia
The Importance of Preserving the Round Ligament in the Repair of Inguinal Hernias in Women
The aim of this study is to evaluate the impact of preserving or not preserving the round ligament during laparoscopic Trans Abdominal Pre-Peritoneal (TAPP) hernia repair on postoperative outcomes in female patients.
- Conditions
- Inguinal Hernia, Femoral Hernia, Obturator Hernia
- Trial name
- NCT06786702
- Testing
- Laparoscopic TAPP (Trans Abdominal Pre-Peritoneal) hernia repair: Round Ligament Preservation, Laparoscopic TAPP (Trans Abdominal Pre-Peritoneal) hernia repair: Round Ligament Cutting
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Muhammet Mustafa Vural
Inguinal Hernia Bilateral, Inguinal Hernia Unilateral
Watchful Waiting Versus Immediate Repair for Occult Contralateral Inguinal Hernias.
This study will compare two ways of managing a small, hidden hernia that can sometimes be found during minimally invasive surgery to repair a hernia on one side of the groin.
- Trial name
- WATCH IT (NCT07461558)
- Testing
- surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, Watchful waiting with supportive care
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- Northwestern University
Hernia, Inguinal
Comparison of Whole Mesh and Split Mesh Use in Laparoscopic Inguinal Hernia Repair
At least 80 patients who will undergo laparoscopic inguinal hernia repair surgery will be randomized into 2 groups. For the patients in the first group, the whole mesh will be laid on the area without being fixed.
- Trial name
- NCT05420376
- Testing
- Split Mesh
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Hernia
Evaluating Changes in Spermatogram Following Bilateral Laparoscopic Inguinal Hernia Repair in Fertile Males
In this prospective open armed study we aim to see if bilateral hernia repair using a mesh alters the spermatogram (sperm count) or testicular volume.
- Trial name
- NCT00282074
- Testing
- laparoscopic bilateral hernia repair
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Postoperative Pain
Pilot Herniorrhaphy Study for Postoperative Analgesia
A Phase 2, Randomized, Pilot Study to Investigate the Safety, Efficacy, Pharmacokinetics and Bioavailability of HTX-011, HTX-002, or HTX-009 Administered Via Injection and/or Topical Application Following Unilateral Open Inguinal…
- Trial name
- NCT02504580
- Testing
- HTX-011, HTX-002, Bupivacaine HCI (Marcaine)
- Where
- 3 sites in United States
- Volunteers
- 463 people
- Sponsor
- Heron Therapeutics
Inguinal Hernia, Postoperative Pain
Comparison of Lornoxicam and Paracetamol for Pre-emptive Intravenous Analgesia for Elective Inguinal Hernia Repair
The purpose of this study is to determine whether lornoxicam or paracetamol is more effective in providing pre-emptive analgesia for adult patients undergoing elective unilateral inguinal hernia repair under general anesthesia.
- Trial name
- NCT01069055
- Testing
- Sterile Saline, Intravenous lornoxicam, Intravenous paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Pain, Postoperative, Postoperative Complications
Open and Laparoscopic Total Extraperitoneal Repair Under Spinal Anesthesia Versus General Anesthesia
Inguinal hernia surgery is one of the most frequently performed procedures among general surgery cases. As with many open surgical methods, this repair is also performed laparoscopically.
- Conditions
- Pain, Postoperative, Postoperative Complications, Inguinal Hernia
- Trial name
- NCT05837013
- Testing
- Spinal anesthesia (with nerve block), General anesthesia (GA)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Konya City Hospital
Inguinal Hernia
Biomechanically Compatible,Minimally Invasive Technique for Recurrence Free Groin Hernia Repair
"A bio-mechanically compatible, minimally invasive technique for recurrence-free groin hernia repair by implantation of Tensiflex mesh prosthesis for the enhancement of the tissue tensile strength of the fascia transversalis."
- Trial name
- NCT04764760
- Testing
- Wing shaped Tensiflex prosthesis
- Where
- United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- St. Joseph Mercy Oakland Hospital
Umbilical Hernia, Inguinal Hernia
The Impact of Medical Clowning on Pain and Stress Level in Pediatric Patients Undergoing Hernia Repair Surgery LAUGH Study.
The purpose of our study to quantitatively examine the stress levels prior to surgery and the use of analgesics post surgery in both children and their parents following a preoperative intervention with a medical clown compared…
- Trial name
- NCT01622218
- Testing
- Medical Clown
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Soroka University Medical Center
Inguinal Hernia, Endotracheal Intubation
Pediatric Inguinal Hernia Repair: Are Muscle Relaxants Necessary? Endotracheal Intubation vs Laryngeal Mask Airway
In prospective, safety-control study; children undergoing laparoscopic inguinal hernia repair using PIRS (Percutaneous Internal Ring Suturing) method will be randomly assigned into four groups.
- Conditions
- Inguinal Hernia, Endotracheal Intubation, Laryngeal Mask, Muscle Relaxants
- Trial name
- NCT02696837
- Testing
- ETT, Proseal LMA, Rocuronium
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Maltepe University
Postsurgical Pain Management
Phase 2/3 Study of TLC590 for Postsurgical Pain Management
A phase 2/3 randomized, double-blind, 2-part, comparator- and placebo-controlled study to assess the safety, pharmacokinetics and efficacy of postsurgical local infiltration in adult subjects following inguinal hernia repair…
- Trial name
- NCT05161637
- Testing
- TLC590, Bupivacain, Ropivacaine
- Volunteers
- 415 people
- Sponsor
- Taiwan Liposome Company
Inguinal Hernia
Modified Guarnieri-Desarda Technique Versus Lichtenstein Technique in Inguinal Hernia Repair
The aim of this study is to compare the surgical outcome of both Lichnichtien tension free mesh hernioplasty of inguinal hernia and the combined modified Guarnieri Desarda technique in terms of postoperative pain, post operative…
- Trial name
- NCT06595628
- Testing
- Lichtenstein Mesh-Based Hernioplasty, Combined Modified Guarnieri-Desarda Tissue-Based Hernioplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Indirect Inguinal Hernia
Comparison of Two Surgical Techniques for Indirect Inguinal Hernia Repair
This study will compare two ways of managing the hernia sac during laparoscopic surgery for an indirect inguinal hernia, a type of groin hernia. A hernia sac is a pouch of tissue that extends through the hernia opening.
- Trial name
- NCT07891845
- Testing
- Standard TAPP Repair With Complete Hernia Sac Dissection, TAPP Repair With Primary Abandon of the Sac
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hitit University
Inguinal Hernia, Analgesia
Dexmedetomidine in TAP Block for Inguinal Hernia Repair
This prospective double-blind randomized study will aim at evaluating the short- and long-term postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane (TAP) block with a combination of local…
- Conditions
- Inguinal Hernia, Analgesia, Pain, Acute, Pain, Chronic
- Trial name
- TAP-dex (NCT04403711)
- Testing
- local anesthetic and dexmedetomidine
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Hernia, Inguinal, Inguinal Hernia, Direct
Study of Laparoscopic Inguinal Hernia Repair
Although mesh fixation has been associated to an increased incidence of nerve injury and involves increased operative costs, many surgeons feel that fixation is necessary to reduce the risk of hernia recurrence.
- Conditions
- Hernia, Inguinal, Inguinal Hernia, Direct, Inguinal Hernia, Indirect, Hernia, Femoral
- Trial name
- NCT02920307
- Testing
- TEP without fixation, TEP with fixation, TAPP without fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Medical Park Gaziantep Hospital
Inguinal Hernia
Telescopic Dissection vs. Balloon Dissection During Laparoscopic TEP Inguinal Hernia Repair
The purpose of this study is to determine if the surgical technique for creation of extraperitoneal space during laparoscopic TEP inguinal hernia repair (telescopic dissection or balloon dissection) has an impact on operative…
- Trial name
- NCT03276871
- Testing
- Telescopic Dissection, Balloon Dissection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic