Clinical trials: Inhalation
Stroke
Diffuse Optical Monitoring With Inhaled Nitric Oxide
This study is a non-randomized, Phase 2 clinical trial designed to measure the cerebral blood flow (CBF) response to inhaled nitric oxide in acute ischemic stroke patients and healthy subjects.
- Trial name
- DOMINO (NCT03023449)
- Testing
- Nitric Oxide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Steven Messe
Chronic Obstructive Pulmonary Disease
An Efficacy and Safety Profile of Inhaled TV48108 in Healthy Volunteers and COPD Patients
The primary objective of the study is to characterize the safety profile and duration of bronchodilation of a single dose of inhaled TV48108.
- Trial name
- NCT02315144
- Testing
- TV48108
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Respiratory Function, Vocal Performance
Combined SOVT and Respiratory Exercises: Effects on MPT and Respiratory Function
This study aims to investigate the effects of combined SOVT and breathing exercises, administered twice weekly for six weeks to conservatory students, through a randomized controlled trial.
- Conditions
- Respiratory Function, Vocal Performance, Voice
- Trial name
- NCT07677501
- Testing
- combined soft and breathing exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Healthy
A Clinical Study to Determine the Safety, Tolerability and Effect of RLS-0071 Doses When Given to Healthy Adults After Inhaling LPS
This is a Phase 1b, randomized, double-blind, placebo-controlled, dose range finding study to assess the safety, tolerability, pharmacodynamics (PK) and pharmacokinetics (PD) of RLS-0071 in healthy adult subjects after challenge…
- Trial name
- NCT05351671
- Testing
- RLS-0071 (10 mg/kg intravenously every 8 hours for total of 3 doses), RLS-0071 (loading dose of 120 mg/kg followed by 40 mg/kg every 8 hours for 2 additional doses)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ReAlta Life Sciences, Inc.
Smartphone Addiction, Postural Disorders
Smartphone Addiction, Posture and Breathing Control in University Students
The aim of this study is to investigate the effects of smartphone addiction on postural problems and breathing control in healthy university students.
- Conditions
- Smartphone Addiction, Postural Disorders, Dysfunctional Breathing
- Trial name
- NCT07615322
- Testing
- Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Anxiety, Panic Disorder
Ventilatory Physiology in Children at Risk for Anxiety
The importance of the proposed research project derives from a steady accumulation of research findings on the relationship between respiration and anxiety.
- Trial name
- NCT00101777
- Where
- United States
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Chronic Obstructive Pulmonary Disease
A Clinical Trial of TQC3721 Suspension for Inhalation
To evaluate the safety, tolerability and pharmacokinetic characteristics of TQC3721 suspension for inhalation in single/multiple administration(s) in healthy subjects; to evaluate the safety,tolerability and efficacy TQC3721…
- Trial name
- NCT05051930
- Testing
- TQC3721 suspension for inhalation
- Where
- China
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Chronic Obstructive Pulmonary Disease
Comparative Effects of ACBT and Slow Expiration in Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is characterized by nonreversible airway obstruction. A diagnosis of COPD is determined by clinical assessment of airflow limitation and symptoms such as cough and wheeze; however, the…
- Trial name
- NCT05922267
- Testing
- ACTIVE CYCLE OF BREATHING TECHNIQUES, SLOW EXPIRATION WITH OPEN GLOTTIS IN LATERAL POSITION
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Asthma, Chronic Obstructive Pulmonary Disease
Trial Comparing Effect of He/O2 to Medical Air on Pulmonary Function Disease
This clinical trial will include healthy volunteers, COPD patients and asthmatic patients who will breathe He/O2 78:22, He/O2 65:35 and medical air consecutively in a randomised order.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Healthy
- Trial name
- NCT00801307
- Testing
- spirometer
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Air Liquide SA
Postpartum Hemorrhage
Comparison of Inhaled Oxytocin (IH) With Intramuscular (IM) Oxytocin in Pregnant Women and With Intravenous (IV) Oxytocin in Healthy Non-pregnant Women
The study will evaluate a stable, dry-powder formulation of oxytocin, with the goal of reducing post-partum hemorrhage morbidity and mortality in resource poor settings.
- Trial name
- NCT02999100
- Testing
- IH Oxytocin, IM Oxytocin, IV Oxytocin
- Where
- 3 sites in Australia, United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Lung Function
Maximal Effort-dependent Respiratory Flow Rates
The general objective of this project is to determine the best method to measure maximal inspiratory flow rates, to study their reproducibility and create reference equations in healthy subjects.
- Trial name
- NCT03197701
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Muscle Aches, Stress
Telerehabilitation-Based Yoga Versus Yoga-Pranayama in University Students
This study will compare two online exercise programs for university students: yoga alone and yoga combined with breathing exercises called pranayama.
- Conditions
- Muscle Aches, Stress, Neck Disorders, Students
- Trial name
- NCT07770139
- Testing
- Yoga-Pranayama, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Altitude Hypoxia
Effect of Acetazolamide on Sleep Disordered Breathing in Lowlanders Older Than 40 Years at Altitude
Randomized, placebo controlled trial evaluating the effect of acetazolamide on sleep disordered breathing in lowlanders older than 40 years travelling from 760 m to 3'100 m.
- Trial name
- NCT03536507
- Testing
- ACETAZOLAMIDE oral capsule
- Where
- Kyrgyzstan
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Labor Pain
Effectiveness of Backside Massage and Lamaze Breathing on Labour Outcome Among Primigravida
The study aims to investigate the effects of a combination of Lamaze breathing exercises and backside massage on the labor experiences of primigravidae in Pakistan.
- Trial name
- NCT06304311
- Testing
- Routine Obstetrics care & Lamaze breathing techniques and backside massage, Routine obstetrics care
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Respiratory Insufficiency
Effect of Neuromuscular Blockade and Reversal on Breathing
In this study the investigators will assess (i) the effect of partial neuromuscular blockade (NMB; TOF ratio 0.8 and 0.6) induced by low-dose rocuronium on the ventilatory response to isocapnic hypoxia and (ii) the effect over…
- Trial name
- BREATH (NCT02845375)
- Testing
- Sugammadex, Neostigmine
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Diabetes Mellitus
A Clinical Trial Assessing the Impact of Inhaled Insulin on Glucose Disposition
To assess the impact of inhalation of insulin on glucose disposition in patients with type 1 diabetes
- Trial name
- NCT00287066
- Testing
- Inhaled Human Insulin, Regular Human Insulin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Pfizer
Manual Therapies, Respiratory Muscle Training
Respiratory Exercises Versus Manual Therapy and Respiratory Exercises in Moderate Smokers
The aim of this study is to assess if an intervention of manual therapy and motor control exercises combined with an inspiratory muscle training program is more effective than an inspiratory muscle training program alone in…
- Conditions
- Manual Therapies, Respiratory Muscle Training, Exercise Therapy, Inspiratory Capacity
- Trial name
- NCT02514161
- Testing
- Inspiratory Muscle training, IMT + Manual Therapy and Motor Control Exercise
- Where
- Spain
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Chronic Obstructive Pulmonary Disease
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects
AZD8871 is a new chemical entity possessing long-acting effect in a single molecule which presents a novel treatment approach to chronic obstructive pulmonary disease [COPD] and potentially also asthma (in combination with an…
- Trial name
- NCT02814656
- Testing
- AZD8871
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthly Volunteers, Women
Psychosocial and Cardiopulmonary Outcomes Following Diaphragm-Focused IMT Training in Healthy Women
The aim of this clinical study is to determine whether diaphragm-focused IMT training has an effect on respiratory, psychosocial, and cardiovascular parameters in healthy women.
- Trial name
- NCT07553039
- Testing
- Inspiratory Muscle Training(PowerBreathe), Inspiratory Muscle Training (%0 MIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Pain, Labor, Anxiety
The Effect of Ylang Ylang Oil and Lemon Oil
This study was conducted as a randomized controlled experimental study.To evaluate the effects of aromatherapy, one of the non-pharmacological pain methods, on labor pain and anxiety in the active phase in primiparous pregnant…
- Conditions
- Pain, Labor, Anxiety, Aromatherapy
- Trial name
- Aromatherapy (NCT05657431)
- Testing
- essential oils (Ylang ylang oil), essential oils (lemon oil)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Özlem Çağan
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