Clinical trials: Inhalation
Sleep Disorders, Sleep Apnea
Electrocardiography Data Analysis in Sleep Disorders
The objective of this study is to determine if a non-invasive technique, using an innovative analysis of electrocardiogram (ECG) data, would allow for detection of respiratory events during sleep and discrimination between…
- Conditions
- Sleep Disorders, Sleep Apnea, Sleep Disordered Breathing
- Trial name
- Holter (NCT02188498)
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Breast Cancer
Evaluation of the Efficacy of Digital Breast Tomosynthesis Imaging
The primary objective of this protocol is to collect the 2-dimensional (2D) screening and diagnostic images, and 3-dimensional (3D) Digital Breast Tomosynthesis (DBT) scans from patient mammography examinations acquired on…
- Trial name
- DBT (NCT01373671)
- Testing
- SIEMENS INSPIRATION DIGITAL BREAST TOMOSYNTHESIS (DBT) SYSTEM
- Where
- United States
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- Siemens Medical Solutions USA - CSG
Pulmonary Fibroses, Idiopathic
Study to Assess CMR316 in Healthy Volunteers and Patients With Idiopathic Pulmonary Fibrosis
The purpose of this study is to assess the safety, tolerability and pharmacokinetics single and multiple inhaled doses of CMR316 in healthy volunteers and patients with Idiopathic Pulmonary Fibrosis (IPF).
- Trial name
- NCT06589219
- Testing
- CMR316
- Where
- Germany
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Calibr, a division of Scripps Research
Prostatic Neoplasm, Urinary Bladder Neoplasm
The Effect of Prolonged Inspiratory Time on Gas Exchange During Robot-assisted Laparoscopic Surgery With Steep Trendelenburg Position : A Crossover Randomized Clinical Trial
Gas exchange disturbance frequently occurs in steep Trendelenburg position during robot-assisted laparoscopic prostatectomy or cystectomy.
- Trial name
- NCT02966535
- Testing
- Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:2 to 1:1), Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:1 to 1:2)
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Insomnia, Cognitive Impairment
The Effect of Aromatherapy on Sleep and Cognitive Level in the Elderly
This research aims to investigate the effect of aromatherapy on sleep duration, sleep quality, falling asleep time and cognitive functions of elderly individuals in the short term and to improve the general health status and…
- Conditions
- Insomnia, Cognitive Impairment, Elderly
- Trial name
- NCT06208800
- Testing
- Blend Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medipol University
COVID-19 Respiratory Infection
A Study to Assess the Safety, Tolerability and Pharmacokinetics of Inhaled HH-120 Aerosol in Healthy Volunteers
This is a Phase 1, randomized, double-blinded, placebo controlled, dose escalation study of HH-120 in healthy adult volunteers. HH-120 is a novel inhalable biologic being developed for COVID-19 treatment.
- Trial name
- NCT05116865
- Testing
- HH-120 Dose 1, HH-120 Dose 2, HH-120 Dose 3
- Where
- Australia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Huahui Health
Athlete
The Effect of Inspiratory Muscle Warm-up on Decreased Diffusing Capacity for Carbon Monoxide After Maximal Exercise in Athletes
This study aims to examine the effects of inspiratory muscle warm-up (IMW) on the gas exchange capacity of the lungs (DLCO) and its potential contribution to recovery and athletic performance in elite athletes from various…
- Trial name
- NCT06751511
- Testing
- General warm-up, Inspiratory muscle warm-up (%40 IMW)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Emre Karaduman
Accident Caused by Snow Avalanche
Physiological Values When Breathing in an Air-pocket. Mountain Lab 2019 (ML2019)
The literature describes and report neurologic intact patients surviving an avalanche several hours after they were buried. The most important factor for surviving more than 15-35 min of burial is considered to be the presence of…
- Trial name
- NCT03911011
- Testing
- Fresh air
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Telerehabilitation, Body Posture
Effects of Pelvic Floor Muscle Training and Diaphragmatic Breathing Exercise on Body Posture
This study; It will be done in order to show evidence of the effects of pelvic floor muscle training and diaphragmatic breathing exercise via telerehabilitation on body posture and quality of life in healthy individuals.
- Conditions
- Telerehabilitation, Body Posture, Pelvic Floor Muscle Training, Diaphragmatic Breathing
- Trial name
- NCT05410704
- Testing
- exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Respiratory Syncytial Virus (RSV)
A Study to Investigate the Safety and Tolerability of Single and Repeat Doses of PC786
This study investigates the safety, tolerability and pharmacokinetics of single and repeat doses of PC786.
- Trial name
- NCT03236233
- Testing
- PC786 - Single doses, PC786 - Repeat doses
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Pulmocide Ltd
Respiratory Aspiration of Gastric Content
Does Adding Milk to Coffee Change Gastric Volume?
The intention of this study is to determine wether coffee added milk change gastric volume in comparison with gastric volume after drinking black coffee
- Trial name
- NCT02361632
- Testing
- Coffee with or without milk
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Inhalational Anthrax
Safety, Tolerability and PK of Intravenous (IV) ETI-204 Alone and in Presence of Ciprofloxacin in Adult Volunteers
Evaluate the safety, tolerability and pharmacokinetics (PK) of intravenous (IV) ETI-204 alone and in the presence of IV and oral ciprofloxacin
- Trial name
- NCT01952444
- Testing
- ETI-204, Ciprofloxacin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Elusys Therapeutics
Healthy
Study Evaluating Inhaled AeroLEF Delivered in 4 Aerosol Delivery Devices in Healthy Volunteers
This was an open-label, two-phase, crossover, safety, pharmacokinetic (PK), and pharmacodynamic (PD) study in normal, healthy, non-smoking, fasting male and female subjects. The first phase (A.
- Trial name
- LEF-07 (NCT00794209)
- Testing
- i.v fentanyl, AeroLEF
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- YM BioSciences
Infection, Pulmonary Disease, Chronic Obstructive
Study in COPD (Chronic Obstructive Pulmonary Disease) Subjects to Investigate Safety, Tolerability, and Pharmacokinetics of Ciprofloxacin After Single Dose Inhalations of 50 mg and 75 mg Ciprofloxacin Inhalation Powder
The purpose of this study is to compare the safety and pharmacokinetics of ciprofloxacin after inhalation of single 52.5 and 48.75 mg doses in COPD patients.
- Trial name
- NCT01168895
- Testing
- Cipro Inhale (Ciprofloxacin, BAYQ3939)
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Bayer
Anxiety, Depression
Impact of Complimentary and Alternative Practices on Patient Wellbeing During Rehabilitation
The study's objective is to assess whether CAM methods are feasible and beneficial in the WSRH setting; to assess stress (using the Perceived Stress Scale-14 and using BioSquares™), anxiety (using the Generalized Anxiety…
- Conditions
- Anxiety, Depression, Stress, Pain
- Trial name
- NCT05082246
- Testing
- Conscious Breathing, Heartfulness Meditation, Emotional Freedom Technique
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Bruxism, Bruxism, Sleep-Related
Diaphragmatic Breathing for Sleep Bruxism in Adults: A Randomized Controlled Trial
The goal of this clinical trial is to learn if a diaphragmatic breathing program can reduce sleep bruxism in adults. The main questions it aims to answer are: Can diaphragmatic breathing lower the frequency of teeth grinding…
- Trial name
- DB4SB (NCT07181642)
- Testing
- Diaphragmatic Breathing Program, Neutral Music Listening
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Accessory Muscle
Activation Patterns of Respiratory Muscles to Loaded Inspiratory Muscle Tests in Healthy Adults Under Different Posture
Whether minimizing sternocleidomastoid (SCM) activation in supine position would increase diaphragm activation during loaded inspiratory muscle tests remains to be determined.
- Trial name
- NCT03729986
- Testing
- Loaded inspiratory muscle test
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Asthma
Comparison of Budesonide and Formoterol Absorption From Budesonide/Formoterol Easyhaler and Symbicort Turbuhaler
The purpose of this study is to compare the test product Budesonide/formoterol Easyhaler with the marketed product Symbicort Turbuhaler in terms of the drug absorbed into the bloodstream.
- Trial name
- NCT01386996
- Testing
- Budesonide/formoterol Easyhaler 320/9 microg, Symbicort Turbuhaler forte
- Where
- Finland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Orion Corporation, Orion Pharma
Asthma, Heart Failure
The General Breathing Record Study
This study will test the use of a new handheld device (called the N-Tidal C), that measures a person's tidal breath carbon dioxide, in diagnosing the cause of someone's breathlessness.
- Conditions
- Asthma, Heart Failure, Pneumonia, Motor Neuron Disease
- Trial name
- GBRS (NCT03356288)
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TidalSense
Tetraplegia, Respiratory Failure
Prospective Study on Swallowing/Breathing Interactions in Severe Guillain Barre Syndrome.
To estimate, in a longitudinal and not invasive way, in patients with SGB at respiratory risk, the function of respiratory muscles and that of the upper airways muscles by investigating the force of the tongue, the gulp, and the…
- Trial name
- DGVSB (NCT01024088)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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