Clinical trials: Inhalation
Healthy
Pharmacodynamic/Pharmacokinetic Interactions Between Oral Roflumilast and Inhaled Formoterol
This Phase I, open, randomized controlled, multiple-dose, parallel-group study investigated the potential pharmacodynamic and pharmacokinetic interactions between multiple doses of oral roflumilast and inhaled formoterol.
- Trial name
- NCT00940329
- Testing
- Roflumilast
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Spinal Cord Injuries
Non-Invasive Spinal Cord Stimulation After Injury
The goal of this study is to assess the function of the lungs and the muscles are used to breathe after individuals receive respiratory training, spinal cord stimulation, a combination of respiratory training and stimulation, a…
- Trial name
- NCT03998527
- Testing
- Transcutaneous Electrical Spinal Cord Stimulation (TcESCS)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Menopause
Relationship Between Genitourinary and Respiratory Symptoms in Postmanopause
The aim of this study is to evaluate the relationship between genitourinary system symptoms and respiratory function and respiratory muscle strength in postmenopausal women.
- Trial name
- NCT07651566
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Halic University
Inspired Oxygen (FIO2), End-tidal Oxygen (ETO2), End-tidal Carbon Dioxide (ETCO2) and Respiratory Rate (RR) Will be Measured Every 30 Seconds
Comparison of the Classic Face Mask Versus NuMask for Preoxygenation
Currently used face mask has certain disadvantages; such as, not providing a complete seal in certain patients, causing hand fatigue after holding the mask in place for more than a few minutes, causing claustrophobia in an…
- Trial name
- NCT01865851
- Testing
- Classic Face Mask and NuMask
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nimmagadda, Usharani, M.D.
Breathing, Sleep Disorder
Effect of Breathing Exercise on Certain Physiological Parameters, Sleep Quality and Vitality in Elderly
Objective: To determine the effect of breathing exercises on certain physiological parameters, sleep quality and vitality in the elderly.
- Trial name
- NCT04469972
- Testing
- Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Aysun Erdal
Chronic Obstructive Pulmonary Disease, Healthy
Ventilation Distribution in COPD Patients During Breathing Exercises
ELTGOL (Slow Expiration with the Opened Glottis in the Lateral posture) is an airway clearance technique performed in the lateral decubitus position.
- Trial name
- NCT06381973
- Testing
- ELTGOL_Physio, ELTGOL_Auto, PEP
- Where
- Belgium
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- William Poncin, PT, PhD
Asthma
A Study of GW685698X in Healthy Japanese Male Subjects
This is a randomized, double blind, placebo controlled, parallel-group, repeat dose study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of inhaled dose from a novel dry powder device in healthy…
- Trial name
- NCT00972673
- Testing
- GW685698X
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Preoperative Care, Child
Reducing Anxiety of Children and Their Parents in the Pre-Operative Process With Therapeutic Play
It is emphasized in studies that child and parent anxiety that arises in pediatric surgery should be prevented or reduced. According to previous studies, one way to reduce child and parent anxiety in the preoperative period is…
- Conditions
- Preoperative Care, Child, Parents, Anxiety
- Trial name
- NCT05540041
- Testing
- Bubble breathing play therapy group, Tell-show-do play therapy group, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Isparta University of Applied Sciences
Pulmonary Disease, Chronic Obstructive
Effect of GSK1160724 In Healthy Volunteers
GSK1160724 is a potent mAChR antagonist, which is being developed for treatment of chronic obstructive pulmonary disease (COPD)
- Trial name
- NCT00555022
- Testing
- GSK1160724, Tiotropium bromide
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Respiratory, Postoperative Pain
The Effect of Pranayama on Pain and Respiration After Coronary Bypass Surgery
After CABG surgery, patients tend to breathe superficially because they experience pain while breathing. By restricting deep inspiration and cough; There is a decrease in lung tidal volume, vital capacity, and functional residual…
- Conditions
- Respiratory, Postoperative Pain, Nursing
- Trial name
- NCT06485531
- Testing
- Pranamaya, Pursed Lips Breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Obstructive Sleep Apnea, Sleep-Disordered Breathing
Tongue Morphology and Posterior Airway Space as Predictors of Response in Patientswith Hypoglossal Nerve Stimulation Therapy
Hypoglossal nerve stimulation (HNS) plays an increasingly important role in managing patients with obstructive sleep apnea (OSA) who do not tolerate CPAP therapy and are not eligible for other alternative treatment options, such…
- Trial name
- NCT06154577
- Testing
- Ultrasonography
- Where
- 2 sites in Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital, Baselland
Obesity
Flintstone Foods 1
This exploratory study is designed to compare the gastric layering and rates of emptying and by inference rates of digestion of a Palaeolithic inspired meal and a reference meal.
- Trial name
- NCT01925053
- Testing
- PAL meal, REF meal
- Where
- United Kingdom
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Asthma
Pharmacokinetic Profile of Four Formulations of Fluticasone Furoate (FF) Using Unit Dose Dry Powder Inhaler (UD-DPI) Compared With FF ELLIPTA® Presentation
This is an open-label, five- period, cross-over, randomized, single dose, single centre study in healthy subjects. This is the second clinical study for the UD-DPI.
- Trial name
- NCT02218723
- Testing
- FF UD-DPI, FF ELLIPTA DPI
- Where
- 2 sites in Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healty Male Volunteers, Athlete
The Effect of Respiratory Muscle Warm-up on Pulmonary Diffusion Capacity in Athletes
Several studies suggest that inspiratory muscle warm-up (IMW) could potentially affect exercise performance; however, its mechanistic basis is still unclear.
- Trial name
- NCT06736236
- Testing
- Inspiratory muscle warm-up, General warm-up (Control)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Emre Karaduman
Chronic Obstructive Pulmonary Disease (COPD)
A First Time in Man Study to Asses the Safety and Tolerability of AZD7624 in Healthy Subjects
This is a First in Human study to assess the safety and tolerability of AZD7624, following inhaled administration of single ascending doses in healthy male volunteers and female volunteers of non-child bearing potential.
- Trial name
- NCT01754844
- Testing
- AZD7624
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Volunteers
Pharmacokinetic Study Comparing Tiotropium Easyhaler® and Spiriva® HandiHaler®
Absorption of inhaled tiotropium is compared between five Tiotropium Easyhaler product variants and Spiriva capsules inhaled via HandiHaler without charcoal.
- Trial name
- TESSA (NCT04850144)
- Testing
- Tiotropium Bromide Monohydrate, Tiotropium Easyhaler with oral activated charcoal
- Where
- Finland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Orion Corporation, Orion Pharma
Asthma, Bioequivalence
A Bioequivalence Study Between Fluticasone Propionate 250 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals vs. FLOVENT DISKUS® 250 mcg/Blister Oral Inhalation Powder /GSK in Healthy Volunteers Under Fasting Conditions
Bioequivalence study between two inhaler products of ffluticasone propionate inhalation powder
- Trial name
- NCT05397834
- Testing
- Fluticasone Propionate 250 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals, FLOVENT DISKUS
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Respirent Pharmaceuticals Co Ltd.
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Healthy
A Single and Multiple Ascending Dose Study With AZD9164 Given for 13 Days in Healthy Male and Female Japanese Subjects
This is a single centre, Double blinded, Randomised, Placebo-controlled, Parallel group study to access the safety, tolerability, and pharmacokinetics of Inhaled AZD9164 after administration of single and Multiple Ascending doses…
- Trial name
- JSMAD (NCT01096563)
- Testing
- AZD9164
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Cholecystectomy, Laparoscopic
The Effect of Breath Exercise on Patients' Post-Operative Anxiety Level, Sleep and Recovery Quality
This study was conducted to determine the effect of breath exercise on post-operative anxiety level, sleep and recovery quality after laparoscopic cholecystectomy surger. This was a randomized controlled experimental study.
- Trial name
- NCT05532436
- Testing
- Breath Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Ataturk University
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