Clinical trials: Inhalation
Healthy Volunteers
Comparison of 30 Units of TI (Technosphere® Insulin) Prepared With Insulin From Two Different Suppliers
A Phase 1, open-label randomized crossover trial in Healthy Volunteers to evaluate the PK/PD of TI (Technosphere® Insulin) prepared with insulin from two different suppliers.
- Trial name
- NCT01982604
- Testing
- TI-Inhalation Powder A, TI-Inhalation Powder B
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Birch Pollen Allergy, Healthy Control Subjects
Effect of the Nasal Provocation on the Breathing Style
The purpose of this study is to find out how the provocation of the nose changes breathing style (specifically, frequency and tidal volume changes)
- Trial name
- NCT02146300
- Testing
- 1. session birch pollen nasal exposure 2. session xylometazoline nasal exposure
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Premenstrual Syndrome, Anxiety
Effect of Sage Essential Oil Inhalation Aromatherapy on Premenstrual Symptoms and Quality of Life
The changes (mood changes, lethargy, irritability, etc.) that gradually disappear with the start of the menstrual period in women are called premenstrual syndrome.
- Trial name
- NCT05823207
- Testing
- sage essential oil
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Cansu Mine Aydin
Body Scan Meditation, Loving-Kindness Meditation
A Large Multi-site Study on Self-administered Mindfulness
The use of self-administered mindfulness interventions has increased in recent years. The effectiveness of these interventions on regulating stress/emotions, however, is debated.
- Conditions
- Body Scan Meditation, Loving-Kindness Meditation, Mindful Breathing Meditation, Mindful Walking Meditation
- Trial name
- NCT06308744
- Testing
- Body-scan meditation, Mindful Breathing meditation, Loving Kindness meditation
- Where
- United Kingdom
- Volunteers
- 2,239 people, healthy volunteers welcome
- Sponsor
- Swansea University
Oncology, Psychological Distress
Music Breathing for Caregivers of Children Newly Diagnosed With Cancer
This proposed pilot randomised controlled trial aims to examine the effect of mobile health-delivered music breathing therapy in enhancing resilience, reducing psychological distress and caregiver strain, and improving the coping…
- Trial name
- NCT06052904
- Testing
- mHealth-delivered music breathing therapy, Online educational modules
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mouth Breathing
Posture and Pulmonary Function of Mouth-breathing Children
The purpose of this study is to characterize the posture and respiratory function of mouth-breathing children.
- Trial name
- NCT01019525
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Heart Disease
The Effect of a Retrofit Particle Trap on the Vascular Effects of Diesel Exhaust Inhalation
The purpose of this study is to determine whether a retrofit particle trap can reduce the adverse vascular responses to diesel exhaust inhalation
- Trial name
- NCT00745446
- Testing
- Forearm Venous Occlusion Plethysmography
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Asthma
Concentrations of Formoterol in Blood and Urine
The purpose of the study is to assess the blood and urine concentrations of inhaled formoterol.
- Trial name
- NCT00914654
- Testing
- inhaled formoterol
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Simple Obesity
Nutritional Video Intervention Using Mindfulness-based Principles
The purpose of this study is to access the acceptability and potential utility of nutritional intervention videos in 1) changing knowledge and attitudes about healthy eating, 2) improving healthy food shopping practices, and 3)…
- Trial name
- NCT02494661
- Testing
- Healthy Cart and Stress Management Videos, Healthy Cart Video
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy
A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD002 in Healthy Subjects
This is a first in human study of ETD002 a new drug being developed for the treatment of cystic fibrosis.The study is a randomised, double-blind, placebo-controlled, interventional study to assess the safety and tolerability of…
- Trial name
- NCT04488705
- Testing
- ETD002 - single dose, ETD002 - 7 day repeat dose, ETD002 - 14 day repeat dose
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Enterprise Therapeutics Ltd
Bioequivalence
A Bioequivalence Study Between Fluticasone Propionate 250 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 250/50 Inhalation Powder/GSK in Healthy Volunteers
Bioequivalence study between two inhaler products of fixed dose combination of fluticasone propionate and salmeterol xinafoate inhalation powder
- Trial name
- NCT03820180
- Testing
- Test Product, Reference Product
- Where
- Greece
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Respirent Pharmaceuticals Co Ltd.
Healthy
Pharmacodynamic Study to Compare Acute Effects of Dihydroergotamine Mesylate (DHE) on Pulmonary Arterial Pressure
Compare the acute effects and tolerability of Dihydroergotamine Mesylate (DHE) delivered by Oral Inhalation (MAP0004) versus by intravenous (IV) infusion in healthy adult volunteers.
- Trial name
- NCT01089062
- Testing
- MAP0004, IV Dihydroergotamine Mesylate (DHE)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Allergan
Quality of Life, Pregnancy Related
Clary Sage Essential Oil & Pregnancy
The purpose of this study is to evaluate the potential for clary sage essential oil to support overall health, wellbeing, and quality of life during the third trimester of pregnancy among otherwise healthy adult women.
- Trial name
- NCT05000424
- Testing
- Clary Sage Massage Oil, Inert Massage Oil
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Early Mobilization, Physiotherapy
Rehabilitation of Patients From the ICU to the Post-hospital Phase
Introduction: Advances in knowledge have contributed to the increase in the number of patients who survive prolonged hospitalization in an Intensive Care Unit (ICU), and, among them, critically ill patients who develop acute…
- Conditions
- Early Mobilization, Physiotherapy, Rehabilitation
- Trial name
- NCT06405529
- Testing
- Early and intensive mobilization protocol at the ICU and Rehabilitation post-hospital discharge
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
COVID-19
Efficacy of Breathox Device Inhalation Therapy in the Treatment of Acute Symptoms Associated With COVID-19 and in the Prevention of the Use of Health Resources
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), the new coronavirus, causes a disease called COVID-19 that can trigger aggressive inflammatory responses.
- Trial name
- BREATH (NCT05196581)
- Testing
- Dispersible NaCl powder 10 sessions, Dispersible NaCl powder 5 sessions
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzana Erico Tanni Minamoto
Sleep Disordered Breathing, Sleep Hypopnea
Apnea Hypopnea Index Severity Versus Head Position During Sleep
This study evaluates the correlation of the position of the head during sleep, independent of the position of the torso, and the severity of apnea hypopneas in obstructive sleep apnea.
- Conditions
- Sleep Disordered Breathing, Sleep Hypopnea, Sleep Apnea, Sleep Apnea, Obstructive
- Trial name
- NCT04086407
- Testing
- Dual-axis inclinometer attached to the subject's forehead with tape
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sleep Systems
Healthy, Blood Pressure
The Effectiveness of the Wim Hof Method
The Wim Hof Method is a multi-disciplinary approach to physical and mental well-being combining cold exposure, breathing exercises, and meditation.
- Conditions
- Healthy, Blood Pressure, Cold Exposure, Stress
- Trial name
- NCT05894031
- Testing
- Wim Hof Method
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Bern
Mucociliary Clearance
Mucociliary Clearance in Healthy Subjects: Comparison of Levalbuterol and Racemic Albuterol
The purpose of this study is to determine whether lung mucociliary clearance (MCC) can be significantly enhanced in healthy subjects by one week of inhalation of nebulized levalbuterol aerosol, as compared to racemic albuterol or…
- Trial name
- NCT00325767
- Testing
- nebulized albuterol (2.5 mg/3ml/dose), nebulized levalbuterol (1.25 mg/3ml/dose)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Obstructive Pulmonary Disease (COPD
Study in Healthy Volunteers and COPD Patients to Evaluate the Efficacy and Safety of Inhaled TV46017
The primary objective of the study is to characterize the safety profile and duration of bronchodilation of a single dose of inhaled TV46017
- Trial name
- NCT02315131
- Testing
- TV46017
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Healthy Adult
Respiratory Measurement of Volume Change Using Accelerometer, Thermographic Camera Electrical Impedance Tomography and Motion Correlation Analysis Using Mattress Sensor in Healthy Individuals
Tidal volume can be the most important technical indicator for ventilation. Measuring the volume of breathing can be used as an indicator of how effective a patient's gas exchange is, and as a predictive indicator of the statue…
- Trial name
- NCT04964245
- Testing
- accelometer, thermographic camera, Electrical Impedance Tomography
- Where
- South Korea
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yonsei University
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