Clinical trials: Inhalation
Pulmonary Disease, Cardiovascular Disease
Cardio-Respiratory Health and Indoor Pollution
The aim of this study is to assess in the sample of population resident in the KHUMBU valley (NEPAL): 1. the respiratory function decline by means of spirometry and the respiratory health by means of questionnaire and six-minute…
- Trial name
- NCT01329159
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Ferrara
Chronic Neck Pain
Effects of Manual Therapy and Exercise Training of Diaphragm in Patients With Chronic Neck Pain
Chronic neck pain is a commonly reported problem and often associated with functional disability. Studies showed that patients with chronic neck pain compensated with changes in breathing pattern.
- Trial name
- NCT04664842
- Testing
- Diaphragmatic Stretch Technique, Breathing Exercise Training
- Where
- Taiwan
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Healthy
Relative Bioavailability of Tiotropium and Salmeterol After Inhalation of a Fixed Combined Dose Compared to Monocomponents in Healthy Male Volunteers
Assessment of the relative bioavailability of a fixed dose combination of tiotropium and salmeterol compared to a free dose combination of the marketed products of tiotropium and salmeterol (Spiriva® and Serevent® Diskus®).
- Trial name
- NCT02254174
- Testing
- Tiotropium/Salmeterol, Serevent® Diskus®, Spiriva®
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Dysfunctional Breathing
Investigation of the Relationship Between Dysfunctional Breathing and Physical Fitness Parameters in Healty Adults
This observational study aims to investigate the relationship between dysfunctional breathing and physical fitness parameters in healthy adults aged 18-35.
- Trial name
- DISFIT (NCT06943027)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Elif Tunç
Panic Disorder
A Trial of the Effect of CVL-865 on Panic Symptoms Induced by Carbon Dioxide Inhalation in Healthy Subjects
The purpose of this study is to determine anxiolytic effect of multiple doses of CVL-865 using an experimental medicine model of carbon dioxide (CO2) inhalation in healthy volunteers.
- Trial name
- NCT04592536
- Testing
- CVL-865 High dose, Alprazolam 1mg XR, CVL-865 low dose
- Where
- Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cerevel Therapeutics, LLC
Overweight and Obesity
ABUNDANCE of A NATURAL ODOUR in HUMAN CEREBROSPINAL FLUID AFTER OLFACTORY EXPOSURE - the OLFO-Brain Study
The goal of this clinical trial is to investigate the abundance of a natural odour in human cerebrospinal fluid in obese and lean participants after inhalation thereof.
- Trial name
- OLFO-Brain (NCT06370845)
- Testing
- Inhalation - Natural Odour
- Where
- 2 sites in Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Bronchial Asthma
Pathophysiologic Changes in the Respiratory System After Fire Smoke Inhalation
Fire smoke inhalation may contribute to intrabronchial inflammation, airway obstruction and impaired gas exchange. In this study the investigators will examine if the scope of inhalation injury can be assessed soon after hospital…
- Trial name
- NCT01240707
- Testing
- Fiberoptic bronchoscopy
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Healthy Adult Females
Effect of Pre-exercise Inhalation of Molecular Hydrogen on Metabolic Response During Graded Exercise in Healthy Women
The goal of this clinical trial is to evaluate if molecular hydrogen can reduce the metabolic response during graded exercise in healthy women aged 18-30 years.
- Trial name
- NCT07644000
- Testing
- Molecular hydrogen
- Where
- Czechia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Palacky University
Acute Pain, Trauma
Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl
The aim of this study is to determinate the equipotent doses of inhaled metoxyflurane vs. intravenous fentanyl.
- Conditions
- Acute Pain, Trauma, Hypovolemia
- Trial name
- NCT03894800
- Testing
- Methoxyflurane (M), Fentanyl (F1), Fentanyl (F2)
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Health-Related Behavior
Yoga With and Without VR for Core, Balance, and Stress in University Students
The present study aims to investigate the combined and comparative effects of yoga exercise performed with and without virtual reality (VR) support on stress levels, core stabilization, and balance in university students aged…
- Trial name
- NCT07310017
- Testing
- Yoga, Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Istinye University
Healthy
Intrapulmonary Pharmacokinetics of ME1100 in Healthy Volunteers
This is a single-center, open-label, single-dose study. The primary objective is to determine Epithelial Lining Fluid (ELF) levels of ME1100 after a single orally inhaled dose.
- Trial name
- NCT01961830
- Testing
- ME1100 inhalation solution
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Dynamic Hyperinflation
Dynamic Hyperinflation During Maximal Voluntary Ventilation in Healthy Subjects
Maximal Voluntary Ventilation (MVV) correlates well with maximal exercise capacity and is used to assess the ventilatory function during exercise in COPD (Chronic Obstructive Pulmonary Disease) patients.
- Trial name
- NCT02831465
- Testing
- Healthy Subjects
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Healthy Volunteers
Pharmacokinetic Study Comparing Tiotropium Easyhaler® and Spiriva® HandiHaler®
Absorption of inhaled tiotropium is compared between five Tiotropium Easyhaler product variants and Spiriva capsules inhaled via HandiHaler without charcoal.
- Trial name
- TESSA (NCT04850144)
- Testing
- Tiotropium Bromide Monohydrate, Tiotropium Easyhaler with oral activated charcoal
- Where
- Finland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Orion Corporation, Orion Pharma
Sleep Disordered Breathing
User Preference/Validation Evaluation of the New Philips Respironics Positive Airway Pressure Application
This pilot study is intended to evaluate the acceptance and performance of the DreamMapper application and the Therapist Assist educational tool in naïve patients with Obstructive Sleep Apnea who have been prescribed Positive…
- Trial name
- NCT03748264
- Testing
- Standard of Care, DreamMapper Application, DreamMapper Application with Therapist Assist
- Where
- 5 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Philips Respironics
Cytokines, Inflammatory
Cytokines and Sevoflurane During Surgery
The aim of the present study was to evaluate the effects of anaesthesia with sevoflurane and surgery on cytokines response.
- Conditions
- Cytokines, Inflammatory, Sevoflurane
- Trial name
- NCT01231477
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Primipara Pregnant
The Effect of Breathing Exercises on Comfort Level in Primiparous Pregnant Women
Pregnancy is a special period in which some changes occur in bio-psycho-social areas and adaptation to these changes is achieved (Üzar and Erkan; 2019).
- Trial name
- breathing (NCT06520930)
- Testing
- breathing exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sibel Kucuk
Healthy
Evaluation of Breathing Effort in Spontaneously Breathing Subjects
The aim of the research project is to evaluate the breathing effort using the Work of Breathing (WoB) and Pressure-Time Product (PTP) parameters, depending on the increasing flow resistance.
- Trial name
- NCT04051645
- Testing
- Breathing through a system with adjustable flow resistance
- Where
- Czechia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Spinal Cord Injuries
Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323945
- Testing
- AIH, Walk, Strength
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Pregnancy Related, Sleep
Sleep in Late Pregnancy - Artificial Intelligence Development for the Detection of Disturbances and Disorders
SLeeP AID4 is a single-group, single-arm, Canada-wide, non-randomised, unblinded, in-home, observational study to prospectively collect and build a data set of natural sleep behaviour and physiology in maternal-fetal dyads (and…
- Conditions
- Pregnancy Related, Sleep, Sleep-Disordered Breathing, Sleep Disturbance
- Trial name
- SLeeP AID4 (NCT05376475)
- Testing
- Infrared video-audio camera, Level III home sleep apnea test, Maternal-fetal transabdominal electrocardiographic heart rate monitor
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Anxiety
Effect of Biofeedback Training to Reduce Anxiety
This study is planned to investigate the effectiveness of EMG, RESP, and TEMP Biofeedback Training to reduce symptoms of anxiety among the nursing students from one school, and to determine whether biofeedback training is…
- Trial name
- NCT05508919
- Testing
- Biofeedback, Writing Sessions
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Karachi
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.