Clinical trials: Inhalation
Obesity
Inspiratory Muscle Strength Training in Adults With Obesity
The purpose of this study is to determine whether inspiratory muscle strength training reduces blood pressure in adults with obesity.
- Trial name
- NCT05459636
- Testing
- High-resistance inspiratory muscle strength training, Very-low-resistance inspiratory muscle strength training
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Florida State University
Rumination
Role of Vagal Tone in Rumination Syndrome
Rumination syndrome is a condition in which people repeatedly and unintentionally regurgitate undigested or partially digested food from the stomach, rechew it, and then either re-swallow it or spit it out.
- Trial name
- NCT03912636
- Testing
- Diaphragmatic breathing, Deep Slow Breathing, Normal breathing
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Alarm Fatigue in Intensive Care Unit Nurses, Psychological Well-Being in Intensive Care Unit Nurses
Effects of Relaxation, Mindfulness, and Breathing Therapy on Alarm Fatigue and Psychological Well-being in Intensive Care Nurses
The goal of this clinical trial is to compare the effects of the Benson Relaxation Technique, mindfulness-based stress reduction meditation, and breathing therapy on reducing alarm fatigue and improving psychological well-being…
- Trial name
- NCT07124364
- Testing
- Benson Relaxation Technique, Mindfulness-Based Stress Reduction Meditation, Breathing Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Hacer Eroglu
Pulmonary Arterial Hypertension
Clinical Study of Inhaled GB002 for Treatment of WHO Group I Pulmonary Arterial Hypertension
This is a Phase 1B, randomized, participant- and investigator-blinded, placebo-controlled, multi-center clinical trial to evaluate the safety, pharmacokinetics (PK), pharmacodynamics (PD), and biomarkers of inhaled GB002 in…
- Trial name
- PAH (NCT03926793)
- Testing
- GB002, Generic Dry Powder Inhaler
- Where
- 14 sites in United States, United Kingdom
- Volunteers
- 8 people
- Sponsor
- GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.
Anesthesia, Breast Cancer
The Impact of Inhalation vs Total Intravenous Anesthesia on the Immune Status and Mortality in Patients Undergoing Breast Cancer Surgery: a Prospective Double-Blind Randomized Clinical Trial.
Even decade ago it was believed that the choice method of anesthesia did not affect the course of the oncological process, but recent evidence has begun to emerge that inhalation anesthesia vs TIVA is associated with a higher…
- Trial name
- TeMP (NCT04800393)
- Testing
- Sevoflurane, Propofol
- Where
- Russia
- Volunteers
- 130 people
- Sponsor
- Moscow Clinical Scientific Center
Coronary Artery Disease
Blood Flow Reserve: Effects After Training With Heavy Inspiratory Exercises
The goal of this single-site, parallel-group, double-blind, sham-controlled randomized control trial is to examine the effect of high-intensity inspiratory muscle strength training (IMST) on coronary blood flow assessed using…
- Trial name
- BREATHE (NCT05632614)
- Testing
- High-intensity IMST, Low-intensity IMST
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Perioperative Complication, Nursing Caries
The Effects of Listening Music During Breathing Exercises
Background and purpose : This study aims to analyze the effects of listening to music during deep breathing and coughing exercises on vital sings and pulmonary functions in patients, who underwent video assisted thoracoscopic…
- Conditions
- Perioperative Complication, Nursing Caries, Pain, Postoperative
- Trial name
- NCT05329519
- Testing
- Listening music
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Ankyloglossia
Analgesic Effect of Inhaled Lavender Essential Oil for Clipping of Tongue-ties
Clipping of the tongue-tie is a common procedure that neonatologists perform in our neonatal unit to help establish breastfeeding.
- Trial name
- LEO-SME1 (NCT04877392)
- Testing
- Lavender essential oil
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- Parc de Salut Mar
Blood Pressure, Heart Rate, Breathing Rate and Oxygen Level
Implementing Peri-operative Mobile Application for Contactless Vital Signs
The huge impact of the COVID-19 pandemic on global healthcare systems has prompted search for novel tools to stem the tide. New digital health tools can provide possible health solutions in this time of unprecedented medical…
- Trial name
- MAC-VITAL (NCT04648111)
- Testing
- Vital sign measurement
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University Health Network, Toronto
COVID-19
Phase I/II Clinical Trial of Recombinant Novel Coronavirus (COVID-19) Vaccine (Adenovirus Type 5 Vector) for Inhalation
This study is a randomized, double-blind, placebo-controlled I/II clinical trial, in order to evaluate the safety and immunogenicity of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) for Inhalation in adults 18…
- Trial name
- NCT04840992
- Testing
- Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) for Inhalation, Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)
- Where
- China
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Chronic Obstructive Pulmonary Disease
Withdrawal of Inhaled Corticosteroids in Patients With COPD in Primary Care
Guidelines recommend inhaled corticosteroids (ICS) for patients with moderate to severe chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00440687
- Where
- United Kingdom
- Volunteers
- 256 people
- Sponsor
- Queen Mary University of London
Obstructive Sleep Apnea of Adult
A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused Breath During Sleep
A study on the effects of daridorexant on nighttime respiratory function in patients with severe obstructive sleep apnea (OSA).
- Trial name
- NCT05458193
- Testing
- Daridorexant
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
COPD
Inspiration Point-A Digital Pulmonary Rehabilitation Tool Management Interventions
The purpose of this study is to measure the feasibility of use of a digital pulmonary rehabilitation tool compared with standard care home program pulmonary rehabilitation.
- Trial name
- NCT03801330
- Testing
- Usual Care Pulmonary Rehabilitation Program, Pulmonary Rehabilitation Software-Based Home Program
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- Blue Marble Rehab Inc
Lung Transplant
CIS001 Extension Study of Cyclosporine Inhalation Solution
This trial is a longterm follow up of a phase III study of inhaled cyclosporine for the prevention of chronic rejection in lung transplant recipients.
- Trial name
- CIS002 (NCT00938236)
- Testing
- Cyclosporine Inhalation Solution (CIS)
- Where
- 16 sites in United States, Canada
- Volunteers
- 17 people
- Sponsor
- APT Pharmaceuticals, Inc.
Patients With Suspected Non-small Cell Lung Cancer (NSCLC) at Clinical Stage T1
Anesthesia Comparison in Early-stage Small NSCLC: A Multicenter RCT
This study is a prospective, randomized, controlled study, which intends to enroll patients with suspected early-stage NSCLC (non-small cell lung cancer) with a diameter of ≤ 3 cm as research subjects.
- Trial name
- NCT07327736
- Testing
- Non-intubated video-assisted thoracic surgery with spontaneous breathing (NIVATS)
- Volunteers
- 410 people
- Sponsor
- Tang-Du Hospital
Hypertension
Salt Study: Inhibited Breathing Pattern and Sodium Inhibitors in Sodium Sensitivity of Blood Pressure
The purpose of this study is to test the hypothesis that blood pressure sensitivity to high sodium intake in healthy humans is characterized by increased urinary excretion of two endogenous sodium pump inhibitors, marinobufagenin…
- Trial name
- NCT00800228
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Essential Hypertension, Aromatherapy
Effects of Aromatherapy in Hypertensive Individuals
Objective: To investigate the effect of aromatherapy on blood pressure and stress response by inhalation and foot massage in individuals with essential hypertension.
- Conditions
- Essential Hypertension, Aromatherapy, Stress, Physiological
- Trial name
- NCT04460300
- Testing
- Aromatherapy-inhalation method, Aromatherapy-foot massage group
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Abant Izzet Baysal University
Asthma; Status
Effects of Swedish Massage Prior Circuit Breathing Training on Asthma
The objective of this study was to determine the effects of Swedish massage prior circuit breathing training on asthma control and respiratory function in patients with asthma.
- Trial name
- NCT06407011
- Testing
- Control, Swedish massage prior circuit breathing training group (SBT), Circuit breathing training group (CBT)
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Scleroderma (Limited and Diffuse)
Respiratory Muscle Training in Scleroderma
The aim of this study is to investigate the effects of IMT on respiratory muscle strength, pulmonary function tests, quality of life aerobic capacity, dyspnea, fatigue and physical activity level in scleroderma patients with ILD.
- Trial name
- NCT06684132
- Testing
- Inspiratory muscle training, Exercise
- Volunteers
- 30 people
- Sponsor
- Firat University
Mechanical Ventilation Complication, Neurological Complication
The Cerebral-Respiratory Interaction During Spontaneous Breathing Ventilation in Neurosurgical Patients (CeRes-SB)
Mechanical ventilation (MV) is a life-saving supportive therapy and one of the most common interventions implemented in intensive care.
- Conditions
- Mechanical Ventilation Complication, Neurological Complication, Respiratory Complication
- Trial name
- CeRes-SB (NCT05363098)
- Testing
- Mechanically ventilated neurosurgical patients
- Volunteers
- 30 people
- Sponsor
- Uppsala University
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