Clinical trials: Inhalation
Acute Distress Respiratory
Sampling in ARDS Patients Under Inhaled Sedation
The main objective of this study is to compare the protein composition of simultaneously collected undiluted pulmonary edema fluid and AnaConDa-S ® fluid from patients with ARDS.
- Trial name
- ANAISS (NCT03964155)
- Testing
- Sample
- Where
- 2 sites in France
- Sponsor
- University Hospital, Clermont-Ferrand
Temporomandibular Joint Dysfunction, Myofunctional Therapy
Temporomandibular Joint Respiratory and Thoracic Region Added to Myofunctional Rehabilitation in Dysfunction Comparison of the Effects of Exercises
In the study, a questionnaire form will be applied to the participants using a face-to-face interview technique. Through the questionnaires, demographic characteristics, pain intensity, location of pain, symptoms of dysfunction…
- Conditions
- Temporomandibular Joint Dysfunction, Myofunctional Therapy, Rehabilitation Exercise
- Trial name
- NCT06883825
- Testing
- Myofunctional Therapy, Myofunctional Therapy + Respiratory Exercises, Myofunctional Therapy + Thoracic Region Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Merve Keskin
Acute Respiratory Distress Syndrome
High Flow Nasal Canula Oxygen Helps Preoxygenate ARDS Patients
Tracheal intubation in the ICU is associated with significant complications and morbidity. Desaturation is among the most frequent and hazardous complication, occurring in almost one out of four intubations, that may in some…
- Trial name
- HIGHER (NCT02214576)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hôpital Louis Mourier
Respiratory Syncytial Virus (RSV)
A Phase II Clinical Study to Evaluate the Efficacy and Safety of YKYY018 for Inhalation Solution
A phase II clinical study to evaluate the efficacy and safety of YKYY018 for inhalation solution in adult participants with respiratory syncytial virus infection
- Trial name
- NCT07808268
- Testing
- YKYY018 for Inhalation Solution
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd.
Asthma
Montelukast Post-marketing Comparative Study With Theophyline Added to Inhaled Corticosteroid (0476-396)
A clinical study explores the safety and efficacy of montelukast and to compare the safety and efficacy of montelukast with those of theophylline in pediatric bronchial asthma patients when they are used in conjunction with…
- Trial name
- NCT00756418
- Testing
- montelukast, Theophylline
- Volunteers
- 84 people
- Sponsor
- Organon and Co
Cystic Fibrosis
Comparison of 2 Treatment Regimens for Eradication of P Aeruginosa Infection in Children With Cystic Fibrosis
Treatment of new Pseudomonas aeruginosa (Pa) infection in cystic fibrosis (CF) can postpone chronic infection. Aim of the study: compare 2 Pa eradication regimens in children with new Pa infection.
- Trial name
- CCTOBI (NCT01400750)
- Testing
- oral ciprofloxacin plus inhaled colistin, TOBI
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colonic Disease
Effect of Lavender Oil Inhalation in Colonoscopy Patients
Aim: In this study, it was aimed to determine the effect of lavender oil inhalation on the anxiety and comfort levels of patients who will undergo colonoscopy.
- Trial name
- NCT05540418
- Testing
- lavender oil inhalation
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Lung Diseases, Sleep Apnea Syndromes
Prevalence of Sleep-Disordered Breathing in Children
To investigate the prevalence and clinical significance of sleep-disordered breathing (SDB) in children.
- Trial name
- NCT00022789
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Milton S. Hershey Medical Center
Cystic Fibrosis
A Study in Adult and Pediatric Patients With Cystic Fibrosis
The purpose of this ascending dose group study is to assess the safety, tolerability, and effects of multiple dose levels of INS37217 and placebo followed by five days twice daily treatment with maximum tolerated dose…
- Trial name
- NCT00034515
- Testing
- denufosol tetrasodium (INS37217) Inhalation Solution
- Volunteers
- 63 people
- Sponsor
- Merck Sharp & Dohme LLC
Sedation, Respiration, Artificial
Dexmedetomidine for Postoperative Sedation in Patients Undergoing Repair of Thoracoabdominal Aortic Aneurysms
The primary objective of this study is to test the hypothesis that time on the ventilator and ICU length of stay will be shorter in TAA patients given postoperative sedation with dexmedetomidine compared to those given standard…
- Conditions
- Sedation, Respiration, Artificial, Length of Stay
- Trial name
- NCT00409344
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Covid-19, Pneumonia, Viral
Inhalation of Ciclesonide for Patients With COVID-19: A Randomised Open Treatment Study (HALT COVID-19)
Randomized open label clinical trial carried out at study centers in Sweden, including Karolinska University Hospital, S:t Göran Hospital, Danderyd Hospital and Västmanlands Hospital.
- Conditions
- Covid-19, Pneumonia, Viral, Sars-CoV2
- Trial name
- HALT (NCT04381364)
- Testing
- Ciclesonide Inhalation Aerosol
- Where
- 11 sites in Sweden
- Volunteers
- 98 people
- Sponsor
- Ola Blennow, MD, PhD
Prematurity, Respiratory Distress Syndrome
CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure
This study seeks to determine if standard continuous positive airway pressure, known as CPAP is as effective as a more complicated approach that generates intermittent increases in airway pressure applied to the nostrils via a…
- Conditions
- Prematurity, Respiratory Distress Syndrome, Apnea of Prematurity
- Trial name
- NICA (NCT03670732)
- Testing
- continuous positive airway pressure, nasal intermittent positive pressure ventilation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Women and Infants Hospital of Rhode Island
COPD (Chronic Obstructive Pulmonary Disease)
Effectiveness of Active Cycle of Breathing Techniques in Patients With Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial
This study aims to examine the effects of Active Cycle of Breathing Technique (ACBT) on pulmonary function, sleep quality, depressive symptoms, and dyspnea in patients with Chronic Obstructive Pulmonary Disease.
- Trial name
- NCT07818187
- Testing
- ACBT+OPEP, Usual Care (Standard Medical Care)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Implantable Cardioverter Defibrillator (ICD), Aromatherapy
Implantable Cardioverter Defibrillator (ICD) Patients and Inhalation Aromatherapy
The effective management of anxiety and fatigue, which lead to negative physical, social, and psychological impacts and increase treatment costs in individuals with implanted cardioverter-defibrillators (ICD), is of great…
- Conditions
- Implantable Cardioverter Defibrillator (ICD), Aromatherapy, Anxiety, Fatigue Symptom
- Trial name
- ICD (NCT06874777)
- Testing
- Aromatherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- TC Erciyes University
Work of Breathing
The Gas Mask: the Effects on Respiration!
Background: The gas mask is used to protect military and non-military subjects exposed to respiratory hazards (CBRN agents). The aim of the study was to evaluate the impact of the gas mask on respiratory patterns and indexes of…
- Trial name
- NCT02782936
- Testing
- measurement of the work of breathing, Gas mask
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Laval University
Sleep Related Breathing Disorder, Congestive Heart Failure
Impact of Resynchronization Therapy on Sleep Disordered Breathing in Advanced Congestive Heart Failure
Background and Introduction: SDB is increasingly recognized as a co-morbidity with significant impact on overall health. The disorder has been implicated in the development of hypertension, atherosclerotic cardiovascular disease…
- Trial name
- IMPACT (NCT00521534)
- Testing
- CRT with atrial overdrive pacing
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Pittsburgh Healthcare System
Ankylosing Spondylitis (AS)
Posture Exercises in Ankylosing Spondylitis
This study will evaluate the effects of posture-focused exercises on spinal alignment in patients with ankylosing spondylitis. Participants will be randomly assigned to one of two groups.
- Trial name
- AS-POSTURE (NCT07879157)
- Testing
- Standard Breathing Exercise Program, Posture-Focused Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Mustafa Akça
Respiratory Failure
Unloading Respiratory Muscles During NIV: Comparison of a Spontaneous and Auto-adjusting Controlled Mode
Measurement of Work of breathing (WOB), as well as pressure time product (PTP) of transdiaphragmatic pressures to evaluate the degree of muscle activity and muscle unloading during non-invasive ventilation.
- Trial name
- NCT00366912
- Testing
- non-invasive ventilation
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Krankenhaus Kloster Grafschaft
Chronic Obstructive Pulmonary Disease
Role of Endorphins in Perception of Dyspnea With Resistive Loading in Chronic Obstructive Pulmonary Disease (COPD)
Endorphins are released in response to breathing difficulty and can modify the perception of breathlessness. In this randomized placebo-controlled trial, resistive breathing loads are used to provoke breathlessness in patients…
- Trial name
- NCT00958919
- Testing
- naloxone, normal saline
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Healthy Subjects
Pharmacokinetics & Tolerability Study of MAP0004 in Smoking and Non-Smoking Adult Volunteers
Compare the pharmacokinetics of Dihydroergotamine Mesylate (DHE) delivered by oral inhalation (MAP0004) or Intravenous (IV) DHE in smokers versus non-smokers.
- Trial name
- NCT01199965
- Testing
- MAP0004, IV DHE
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Allergan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.