Clinical trials: Inhalation Pneumonia
COVID-19, Respiratory Failure With Hypoxia
Elmo Respiratory Support Project - COVID-19
The number of COVID-19 cases has been growing exponentially, so that the industrialized economies are facing a significant shortage in the number of ventilators available to meet the demands imposed by the disease.
- Trial name
- NCT04470258
- Testing
- ELMO PROJECT AT COVID-19: STUDY IN HUMANS, ELMO PROJECT AT COVID-19: PROOF OF CONCEPT AND USABILITY
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Escola de Saúde Pública do Ceará
COPD, Inhaled Corticosteroid
Eosinophil-guided Reduction of Inhaled Corticosteroids
Clinical trial on eosinophil-guided time-updated person-specific reduction of inhaled corticosteroid (ICS) therapy and prophylactic azithromycin therapy in patients with severe or very severe chronic obstructive pulmonary disease…
- Conditions
- COPD, Inhaled Corticosteroid, Azithromycin, COPD Exacerbation
- Trial name
- COPERNICOS (NCT04481555)
- Testing
- Azithromycin, ICS
- Where
- 9 sites in Denmark
- Volunteers
- 444 people
- Sponsor
- Chronic Obstructive Pulmonary Disease Trial Network, Denmark
Nosocomial Pneumonia
High-dose Inhaled NO Therapy for the Prevention of Nosocomial Pneumonia After Cardiac Surgery With CPB
The primary aim of this single-center, prospective, randomized, controlled, pilot study is to test the hypothesis that inhalation of NO 200 ppm prevents the development of nosocomial pneumonia in patients at risk after cardiac…
- Trial name
- NCT06162455
- Testing
- 200- ppm NO
- Where
- Russia
- Volunteers
- 74 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Cough
An Investigation Into the Mechanism of Inhalation Cough Challenge
Despite its commonplace use in respiratory medicine the mechanism whereby inhalation challenge with a variety of mild acid aerosols produces a dose related and predictable cough is unknown.
- Trial name
- NCT02039999
- Testing
- Nebulised citric acid in serial dilutions, Nebulised ATP solution in serial dilutions, Nebulised TRPA1 agonist solution in serial dilutions
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
COVID-19
Responses to CPET in Subjects With Persistent Exercise Intolerance After COVID-19: an Open-Source Exercise Network
This retrospective collaborative study on persistent exercise intolerance after COVID-19 offers to perform a large descriptive analysis of CPET performed in real-life by pulmonologists, cardiologists and physiologists.
- Trial name
- NCT05532995
- Where
- 29 sites in Canada, France and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Association pour la Complementarite des Connaissances et des Pratiques de la Pneumologie
COVID-19 Infection
A Trial of a Next Generation COVID-19 Vaccine Delivered by Inhaled Aerosol
The goal of this clinical trial is to study the safety of a new inhaled vaccine to prevent COVID infection and learn about the immune responses that are made in the lungs and the blood after vaccination.
- Trial name
- AeroVax (NCT06381739)
- Testing
- ChAd-triCoV/Mac, Control
- Where
- 2 sites in Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- McMaster University
COVID-19 Acute Respiratory Distress Syndrome
Interleukine 6 (IL6) Assay for Predicting Failure of Spontaneous Breathing in Patients With COVID-19 Acute Respiratory Distress Syndrome
In the current COVID-19 pandemic, many patients have an acute respiratory distress syndrome (ARDS). Among mechanisms related to COVID-19 acute respiratory distress syndrome, cytokine storm and secretion of IL-6 play a central…
- Trial name
- NCT05330845
- Testing
- IL6 assessment, CRP and PCT assessment
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Henri Duffaut - Avignon
Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia
Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure
This prospective observational study will evaluate the safety and performance of the MiniLung petite kit in neonatal and pediatric patients with acute respiratory and cardiac failure.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia, Acute Respiratory Failure, Acute Lung Injury
- Trial name
- PETIT (NCT06750536)
- Testing
- MiniLung petite kit combined with the Xenios console
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Xenios AG
COVID-19 Pandemic
Effects of Diagrammatic Breathing With and Without Resistance in Post Covid Patients on ADLs
Effects of diaphragmatic breathing exercise with and without resistance exercise program on functional capacity and activity of daily living in post covid patients
- Trial name
- NCT05543551
- Testing
- Diaphragmatic breathing with Resistance Training, diaphragmatic breathing with out resistance training
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
SARS-CoV-2 Infection
Chronic Mouth Breathing and SARS-CoV-2 Positivity in the Pediatric Population
Numerous non-scientific articles on the internet assert the significance of nasal breathing in protecting against COVID-19. Although nasal breathing is anticipated to result in a reduced intake of bioparticles when compared to…
- Trial name
- BREATH-COV (NCT07063134)
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people
- Sponsor
- Dokuz Eylul University
COVID-19
CovidDB: The Covid-19 Inpatient Database
The aim of the project is to better understand the Covid-19 inpatient course of the disease and to quickly identify the positive experiences in the treatment in order to update guidelines for the treatment and use of medication.
- Trial name
- NCT04344171
- Where
- 9 sites in Germany, Romania
- Volunteers
- 5,000 people
- Sponsor
- ClarData
COVID 19
Inhaled Ciclesonide for Outpatients With COVID19
The CONTAIN (CiclesOnide cliNical TriAl covId-19 treatmeNt) is a randomized control study of ciclesonide vs placebo for mild covid-19 disease. The need for potential therapy for COVID-19 patients is urgent.
- Trial name
- CONTAIN (NCT04435795)
- Testing
- Ciclesonide, Ciclesonide nasal
- Where
- 3 sites in Canada
- Volunteers
- 215 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Early Aspiration Pneumonia
Bronchial Alpha Amylase as a Marker for Early Aspiration Pneumonia in Therapeutic Hypothermia.
Early Aspiration Pneumonia is a frequent and dreadful complication in survivors of cardiac arrest. Therapeutic Hypothermia widely used in Intensive Care Unit for its benefice on post cardiac arrest syndrome may otherwise hide…
- Trial name
- NCT03007862
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Respiratory Failure
Occurrence of Ventilator Associated Pneumonia in Italian ICU Using Cuffed Tracheostomy Tubes With Subglottic Secretion Drainage
Ventilator-associated pneumonia (VAP) is a serious complication and carries increased risks of morbidity and mortality for patients who require mechanical ventilation.
- Trial name
- VICTOR (NCT02223988)
- Testing
- subglottic secretion removal
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Turin, Italy
Coronavirus, Inspiratory Muscle Training
Association of Inspiratory Muscle Training With HD-tDCS for Assistance to Patients With Long Covid-19
COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e.
- Conditions
- Coronavirus, Inspiratory Muscle Training, Respiratory Infection, COVID-19
- Trial name
- NCT05359770
- Testing
- Active HD-tDCS, Control group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Suellen Marinho Andrade
Chronic Obstructive Pulmonary Disease (COPD)
Aclidinium/Formoterol Fixed Combination Dose Finding Study
The study seeks to determine the optimal dose of the Aclidinium/Formoterol combination for investigation in Phase III clinical trials
- Trial name
- NCT00626522
- Testing
- Aclidinium bromide and formoterol
- Where
- 9 sites in Australia, Czechia and 2 more
- Volunteers
- 808 people
- Sponsor
- AstraZeneca
Breathing, Mouth, Pneumonia
Mouth Odor on Preventing Pneumonia by Oral Frailty
This research plan aims to first collect data on the oral function and oral hygiene status of the elderly population in the community and to understand the normal model of oral frailty among the older adults in the community.
- Conditions
- Breathing, Mouth, Pneumonia, Frailty
- Trial name
- NCT05987982
- Testing
- Oral exercises and oral hygiene, Oral care
- Where
- Taiwan
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Covid19, Hydrogen-oxygen Gas
Hydrogen-oxygen Gas Mixture Inhalation in Patients With Convalescent Coronavirus Disease 2019 (COVID-19)
This study is a multicenter, randomized, open, parallel-controlled study. Qualified subjects will randomly be assigned to the experimental arm or the control arm according to the ratio of 1:1, with age (> 60 years or ≤ 60 years)…
- Conditions
- Covid19, Hydrogen-oxygen Gas, AMS-H-03
- Trial name
- NCT04594460
- Testing
- Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03, OLO-1 Medical Molecular Sieve Oxygen Generator
- Where
- 2 sites in China
- Volunteers
- 198 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Long Covid
SingStrong: Strong Lungs Through Song - Long COVID-19 Study
Evidence is emerging that many individuals who recover from Covid-19 are experiencing a range of residual problems. These include fatigue, pain, reduced exercise tolerance and breathing issues.
- Trial name
- ss (NCT04810065)
- Testing
- SingStrong: Strong lungs through Song
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University of Limerick
Covid19, Respiratory Disease
Inspiratory Muscle Training in Patients With COVID-19
COVID 19 has become a pandemic and has led to high demand on healthcare systems. It can cause a severe acute respiratory syndrome (SARS CoV-2) which leads to a long hospital stay, developing important functional damage and making…
- Trial name
- NCT04603963
- Testing
- power breathe
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- Elaine Cristina Pereira <elaine.cpereira@einstein.br>