Clinical trials: Inhibition
Ovulation, Ovulation Inhibition
Can Ibuprofen Delay Ovulation in Natural Cycle-IVF?
During natural cycle in vitro fertilisation, no gonadotropin stimulation is used to stimulate oocyte production. Ovulation is induced with HCG (human chorionic gonadotropin) and the follicle is retrieved 36 hours later.
- Conditions
- Ovulation, Ovulation Inhibition, Ovulation Inhibition/Drug Effects, Pregnancy
- Trial name
- Ibudelay (NCT02571543)
- Testing
- Ibuprofen
- Where
- Switzerland
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Attention Deficit Hyperactivity Disorders
Low-dose vs. Normal-dose Psychostimulants on Executive Functions in Individuals With ADHD
This double-blind crossover study aims to compare cognitive performance (e.g., working memory, selective attention and cognitive flexibility) of children ages 6-18 years diagnosed with ADHD of the combined type (ADHD-C) or…
- Trial name
- NCT02167048
- Testing
- Psychostimulants
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Smoking Cessation, Inhibition (Psychology)
Aerobic Exercise and Inhibitory Control
Although more than half of Canadian smokers in 2015 attempted to quit, with one-third attempting more than once, successful smoking cessation (quitting) remains a challenge.
- Trial name
- AMIAEIC (NCT03441737)
- Testing
- Exercise, Non-Exercise
- Volunteers
- healthy volunteers welcome
- Sponsor
- Western University, Canada
Osgood-Schlatter Disease
Rate of Torque Development in Adolescents With Osgood-Schlatter
Osgood-Schlatter is a growth-related condition involving multiple different types of tissue in the tendon-bone interface at the tibial tubercle.
- Trial name
- NCT05789095
- Testing
- Rate of torque development testing of knee flexors and knee extensors using a fixated handheld dynamometer (MicroFet 2, Hoggan, Scientific L.L.C., Salt Lake City, USA), sampling rate of 100hz)
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Pediatric Obesity, Inhibition
Brain Mechanisms of Overeating in Children
The proposed research will follow healthy weight children who vary by family risk for obesity to identify the neurobiological and appetitive traits that are implicated in overeating and weight gain during the critical…
- Conditions
- Pediatric Obesity, Inhibition, Decision Making, fMRI
- Trial name
- RO1 (NCT03341247)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Penn State University
Tinnitus, Hearing Loss
Investigating Disinhibitory Brain Mechanism in Tinnitus and Hearing Loss
Tinnitus, the perception of sound in the absence of an external acoustic stimulus. Tinnitus is often perceived inside the head rather than the ear and is a common condition with a prevalence estimated between 10 and 15% in…
- Trial name
- IGNITE (NCT04862572)
- Testing
- MRI scanning
- Where
- 3 sites in United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Idiopathic Parkinson's Disease
Dopamine Effect on Inhibitory Control
The effect of Levodopa medication on inhibitory control in Parkinson's patients is extremely debated despite the fact that this has potential clinical and therapeutic implications.
- Trial name
- DEI (NCT03665493)
- Testing
- PD patients H&Y=1.5-2 Medications ON, PD patients H&Y=1.5-2 Medications OFF, Healthy age-matched controls
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Giovanni Mirabella
CBD, Fear
Effects of Cannabidiol (CBD) on the Brain
Cannabidiol (CBD) is a phytocannabinoid that is one of 113 identified cannabinoids in the cannabis plant. It is derived from the hemp plant, and may treat conditions like pain, insomnia, and anxiety.
- Conditions
- CBD, Fear, Inhibition
- Trial name
- CBD (NCT04831294)
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Auburn University
Behavioral Inhibition, Anxiety
A Multi-Method Early Intervention Program for Inhibited and Anxious Preschoolers
This project aims to develop and evaluate a novel early intervention program that targets the specific risk factors implicated in the development and persistence of shyness, social reticence, and withdrawal in children.
- Trial name
- NCT03486860
- Testing
- Parent Psychoeducation, Turtle Program
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Attentional Control Switching, Task Switching Between Modalities
Yoga Practice, Stress and Cognitive Performance
It has been indicated in recent research that Mindfulness-based interventions may offer possibilities of promoting human stress processing and reducing anxiety or depression.
- Conditions
- Attentional Control Switching, Task Switching Between Modalities, Inhibition, Stress
- Trial name
- NCT05232422
- Testing
- Hatha yoga course
- Where
- Austria
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Noisy Environment
This study aims to examine whether listening to natural sounds in a noisy (traffic) environment compared to traffic noise only impacts behavioural, cognitive, affective, and physiological markers associated with attention…
- Conditions
- Cognitive Fatigue, Mental Fatigue, Heart Rate Variability, Skin Conductance
- Trial name
- EARS (NCT05009784)
- Testing
- Baseline, Fatigue Manipulation, Traffic Sound
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration Outdoors
This study aims to examine whether listening to natural sounds in a noisy outdoor environment compared to no natural sounds influences behavioural, cognitive, affective, and physiological markers.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- NEO (NCT05679882)
- Testing
- Masking Sounds, No Masking Sounds
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Food Response, Food Stop
Inhibitory Capabilities Among Women With Eating Disorders
The goal of the study is to increase the flexible behavior toward food via inhibition training among restrained eaters. The expectation is that the train will increase food consumption, decrease food-related anxiety and affect…
- Conditions
- Food Response, Food Stop, Food Response-inhibition
- Trial name
- NCT05553574
- Testing
- Stop signal food task
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Adjustment Disorder With Work Inhibition
Neurobiological Effects of Work-related Adjustment Disorder
INTRODUCTION: Stress is one of the greatest burdens of our society and often imply impairments in cognitive and emotional functions.
- Trial name
- NeuroWAD (NCT03334045)
- Testing
- PET/MR scans
- Where
- Denmark
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cognitive Change, Processing, Visual Spatial
Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Function
The investigators' study is designed to test whether brief exposure to a martial arts-based intervention (a coordinative, partnered training exercise known as "Hubod"), can improve cognitive function to a greater degree than…
- Conditions
- Cognitive Change, Processing, Visual Spatial, Inhibition (Psychology), Working Memory
- Trial name
- HUBOD (NCT04760054)
- Testing
- HUBOD, Active Comparator, Control Condition
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Interleukin-6 Inhibition, Physical Stress
Acute Exercise and NK Cell Regulation in Tissue and Circulation After IL-6R Blockade
The study is a randomized controlled trial studying the acute effect of intense aerobic exercise upon NK (Natural Killer) cell activation and appetite-regulation in human participants with or without concommitant IL-6R receptor…
- Conditions
- Interleukin-6 Inhibition, Physical Stress, Appetitive Behavior
- Trial name
- NCT04616235
- Testing
- Tocilizumab Injectable Product, Saline 0.9% 100 ml NaCl 0.9% will be infused over 1 hour
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Executive Function
The Order Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function.
- Trial name
- NCT05314699
- Testing
- resistance-aerobic exercise, RA, aerobic-resistance exercise, AR
- Where
- Taiwan
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Tic Disorders
Neuromodulation of Inhibitory Control in Tic Disorders
The present study aims to assess the effects of non invasive electrical stimulation of the vagus nerve via transcutaneous vagus nerve stimulation (tVNS) on cognitive functions, inhibitory and tic control in patients with tic…
- Trial name
- NCT05263414
- Testing
- tVNS
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Inhibition
Exploring the Impact of Biofeedback on the Inhibitory Control of Healthy Older Adults
Inhibitory control refers to the conscious and voluntary suppression of predominant responses when they are automatic, inappropriate, or incorrect.
- Trial name
- I-BF (NCT04925830)
- Testing
- Heart rate variability biofeedback; haemoncephalography biofeedback
- Where
- Switzerland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Drug-drug Interaction
Inhibition Metamizole 2020
This clinical phase I trial had 3 arms: inhibition by fluconazole, inhibition by ciprofloxacin and placebo. Subjects were treated for 3 days prior to the study day. The intervention was a single dose of 1 gram metamizole.
- Trial name
- NCT04621253
- Testing
- Novalgin
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland