Clinical trials: Injectables
Intrabony Periodontal Defect
Clinical Evaluation of Injectable Alb-PRF in the Management of Intrabony Defect in Stage-III Periodontitis Patients
Clinical Evaluation of Injectable Albumin Platelet Rich Fibrin Versus Platelet Rich Fibrin in the Management of Intra-bony Defect in Stage-III Periodontitis Patients.
- Trial name
- NCT06297577
- Testing
- Albumin Platelet Rich Fibrin (Alb-PRF) combined with minimally invasive surgical technique (MIST), Minimally invasive surgical technique (MIST)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ridge Preservation, Alveolar Bone Loss
Evaluation of Autogenous Demineralized Dentin Graft for Ridge Preservation With and Without Injectable Platelet Rich Fibrin
Ridge preservation should be considered whenever possible after tooth extraction. Whether implant placement would be performed or for aesthetic consideration at pontic sites when conventional bridge is planned.
- Conditions
- Ridge Preservation, Alveolar Bone Loss, Dentin Graft
- Trial name
- NCT05437172
- Testing
- injectable platelet rich fibrin with demineralized dentin graft, demineralized dentin graft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Inflammatory Gingival Enlargement
Effect of I-PRF After Gingivectomy
The goal of this clinical trial is to evaluate the effect of injectable platelet-rich fibrin application on wound healing following gingivectomy or gingivoplasty.
- Trial name
- I-PRF (NCT07174934)
- Testing
- application of injectable platelet-rich fibrin on the wound area .
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Atrophic Acne Scarring
Poly-L-Lactic Acid in Atrophic Acne Scars
Background: Management of atrophic acne scars remains challenging due to their heterogeneous morphology and suboptimal response to conventional therapies.
- Trial name
- NCT07523217
- Testing
- injectable PLLA, PLLA threads
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
General Anesthesia
Efficacy and Safety of HSK3486 Compared to Propofol for Adults Undergoing Elective Surgery With General Anesthesia
To demonstrate HSK3486 0.4/0.2 mg/kg (0.4 mg/kg intravenous [IV] slow injection over 30 [±5] seconds for the first dose, an additional 0.2 mg/kg if needed) is non-inferior to propofol 2.0/1.0 mg/kg (2.0 mg/kg IV slow injection…
- Trial name
- NCT05478174
- Testing
- HSK3486, Propofol
- Where
- 23 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
Oral Pre-exposure Prophylaxis (PrEP), Long-acting Injectable Cabotegravir for PrEP
PathToScale: An Implementation Evaluation
The purpose of this study is to evaluate the implementation and clinical outcomes of expanded pre-exposure prophylaxis delivery modalities and service delivery points offering long-acting injectable cabotegravir and oral…
- Trial name
- NCT06319105
- Testing
- Standard intervention: Offer PrEP choice
- Where
- Malawi
- Volunteers
- 9,900 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Pain
EXPAREL for Minimally Invasive Supracervical Hysterectomies
The aim of the of the study is a reduction in minimally invasive supracervical hysterectomy postsurgical pain, which may result in less need for supplemental opioid pain medications, fewer opioid related adverse events, and a…
- Trial name
- NCT03769714
- Testing
- Saline Solution for Injection, Exparel
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
HIV Infections, Contraception
Pharmacokinetic Study of Long-acting Antiretrovirals and Contraceptives in HIV
This study is being done to understand how long-acting injectable cabotegravir (CAB-LA) used for HIV pre-exposure prophylaxis (PrEP) and hormonal contraceptive methods affect each other when used at the same time.
- Conditions
- HIV Infections, Contraception, Drug-drug Interaction, PrEP
- Trial name
- PHARAOH (NCT07516548)
- Testing
- Long-acting injectable cabotegravir (CAB-LA), No PrEP
- Where
- Botswana
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Platelet-rich Fibrin
Effect of Injectable Platelet-rich Fibrin on the En Masse Retraction of Maxillary Anterior Teeth
The aim of this study is to investigate the effect of local injection of injectable platelet rich fibrin (i-PRF) on the rate of orthodontic en masse retraction of anterior teeth clinically and to report any associated pain as…
- Trial name
- NCT05608356
- Testing
- injectable platelet rich fibrin(i-prf)
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
HIV Infections
The Implementation of Pre-exposure Prophylaxis of Injectable Cabotegravir
Although CAB LA PrEP has been proven efficacious in blinded randomized controlled clinical trials, additional research is needed to evaluate effectiveness in real world settings as well as to identify effective implementation…
- Trial name
- ImPrepCab (NCT05515770)
- Testing
- Cabotegravir Injection
- Where
- Brazil
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Midface Volume Deficit
Safety and Effectiveness of Mosaic for the Treatment of Midface Volume Deficit
The goal of this clinical trial is to study whether the Mosaic Injectable Dermal Implant is a safe and effective treatment for age-related midface volume deficit in adults who are at least 22 years of age.
- Trial name
- PRIME (NCT07710443)
- Testing
- Injectable dermal implant
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Helios Aesthetics Inc.
Psychotic Disorders
Family Perspectives:Treatment of Psychiatric Illnesses With Atypical Long Acting Injectable Antipsychotic Medication
Patients who have schizophrenia, schizoaffective disorder, a psychotic disorder, and are being treated with a medication called Risperidone Long Acting Injectable medication or another antipsychotic medication are candidates for…
- Trial name
- NCT00287027
- Testing
- Risperdal Long Acting Injectable Antipsychotic Medication
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Alliance on Mental Illness New Hampshire
Mid-facial Volume Deficit Related to Aging
Safety and Effectiveness of Juvéderm® VOLUMA XC Injectable Gel for Cheek Augmentation
Multicenter, single-blind, randomized, "no-treatment" control study to demonstrate the safety and effectiveness of VOLUMA XC for deep injection for cheek augmentation to correct age-related volume deficit in the mid-face.
- Trial name
- NCT00978042
- Testing
- Juvéderm® VOLUMA XC
- Where
- 2 sites in United States, Canada
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Allergan
Face; Atrophy
DA-13-007 Versus Sculptra for the Treatment of Nasolabial Folds Wrinkles
Study DA-13-007 is a randomized, evaluator-blinded, within subject (split face) multicenter clinical study of DA-13-007l (Injectable poly-l-lactic acid) compared to SCULPTRA in the treatment of nasolabial fold wrinkles.
- Trial name
- NCT02310490
- Testing
- DA-13-007 right with left side Sculptra left side, DA-13-007 left with left side Sculptra right side
- Where
- 4 sites in United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- DermAvance
Periodontitis (Stage 3)
Evaluation of The Periodontal Parameters Following Non-Surgical Periodontal Therapy With and Without Adjunctive Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical Trial
This randomized controlled clinical trial aims to evaluate the effectiveness of non-surgical periodontal therapy (NSPT) with and without the adjunctive use of injectable platelet-rich fibrin (I-PRF) in patients with chronic…
- Trial name
- NCT07090265
- Testing
- non-surgical periodontal therapy, non-surgical periodontal therapy + I-PRF
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental, Implant Osseointegration
Validity of Ozonated Olive Oil Gel Versus Injectable Bone Graft
Many of studies have been performed to improve osseointegration and bone density around implants by modifying the implant by adding bone graft or substitute material that increase success of implant.
- Conditions
- Dental, Implant Osseointegration, Ozone Therapy, Bone Graft
- Trial name
- NCT07368114
- Testing
- Immediate implant placement, β-tricalcium phosphate Injectable Bone Graft, Ozonated olive oil gel
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Skin Aging
Randomized Trial of Combination Treatment With Sofwave and Sculptra
Evaluation of treatment on the upper arm with Sculptra and Sofwave on the same day versus Sofwave followed by Sculptra 1 month later.
- Trial name
- NCT07342452
- Testing
- Sofwave, Sculptra
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Micropenis
Shafer Width and Girth: The Use of Injectable Fillers for Penile Enhancement
Injectable filler will be performed by Principal Investigator under sterile conditions for the enhancement of girth and surface area of the penis.
- Trial name
- NCT04755634
- Testing
- Hyaluronic Acid
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shafer Clinic Fifth Avenue
Lichen Planus
Use of Injectable Platelet Rich Fibrin in Lichen Planus
Platelet Rich Fibrine (PRF), which promotes wound healing by supporting angiogenesis, immunity and epithelial proliferation phases.
- Trial name
- NCT03265093
- Testing
- Platelet Rich Fibrin Injection, Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Monitored Anesthesia Care
A Study to Characterize Pharmacokinetics (PK) and Pharmacodynamics (PD) of LUSEDRA® Administered as Continuous Infusion or Bolus Compared With Continuous Infusion of Propofol Injectable Emulsion
The purpose of this study is to explore the pharmacokinetics (PK) and pharmacodynamics (PD) of LUSEDRA® administered as a continuous infusion or bolus compared with continuous infusion of propofol injectable emulsion.
- Trial name
- NCT01308541
- Testing
- arm 1, LUSEDRA, Propofol (arm 3)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.