Clinical trials: Injection Pain
Pain
Skin-to-skin Contact for Newborn First Injection Pain
This study is carried out to examine the effect of skin-to-skin contact on the pain and stress level of the first intramuscular injection after elective cesarean section.
- Trial name
- NCT05700552
- Testing
- skin to skin contact
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Jet Injection, Local Anasthesia
This Study Evaluate the Patient Response to Jet Injection, Pain and Satisfaction Compared to Conventional Method of Local Anasthesia Especially in Maxillary Teeth
Pain during administration of local anesthesia remains one of the major concerns in dental practice, often leading to anxiety and treatment avoidance.
- Trial name
- NCT07581249
- Testing
- Non aspirating dental syringe, The use of jet injection
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain, Acute Pain
Pain Induced by m-Cresol as Preservative
Preservatives such as m-Cresol are essential components in many subcutaneously injected medications, including insulin or human growth hormone, to prevent bacterial growth.
- Conditions
- Pain, Acute Pain, Healthy Volunteer Study
- Trial name
- NCT07600814
- Testing
- m-Cresol 0.1%, m-Cresol 0.25%, Control Solution
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Post-operative Pain
Marcaine Use in Laparoscopic Gynecological Surgery
The purpose of this trial is to compare incisional pain in patients receiving pre-incisional versus post operative Marcaine injection.
- Trial name
- Marcaine (NCT01861665)
- Testing
- Marcaine- 0.25%, Marcaine 0.25%.
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Symptomatic Irreversible Pulpitis
Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain
The aim of this study is to determine whether inferior alveolar nerve block of ketorolac and lidocaine would improve the success rate in teeth with symptomatic irreversible Pulpitis.
- Trial name
- IANB (NCT03410212)
- Testing
- Ketorolac Tromethamine
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Pain Measurement, Visual Analog Pain Scale
The Analgesic Effect of Intrathecal Hydromorphone Injection on Spinal Anesthesia
The purpose of this study is to evaluate the adequate dose of intrathecal hydromorphone injection for postoperative pain relief after knee arthroscopic surgery.
- Trial name
- NCT01172782
- Testing
- Hydromorphone
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Osteoarthritis, Knee
Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
This study will evaluate the use of a local injection around the knee (periarticular) during total knee replacement (TKR) surgery to see if it reduces postoperative pain levels.
- Trial name
- NCT02570503
- Testing
- Ropivacaine, Ketorolac, Clonidine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Pain, Intramuscular Injection
The Effect of ShotBlocker on Injection Pain
Shotblocker is an effective approach to reduce injection pain. Generally, injection pain has been studied in children, but reducing injection pain in adults is an important issue.
- Trial name
- NCT05495542
- Testing
- ShotBlocker
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bornova No. 25 Mevlana Family Health Center
Pain, Acute, Analgesia
Preanesthetic Analgesia/Nociception Index (ANI) and Propofol Injection Pain
Recently, Analgesia Nociception Index (ANI) has been evaluated for objectively measuring peri-operative pain and to guide intra-operative opioid administration during various surgeries.
- Conditions
- Pain, Acute, Analgesia, Nociceptive Pain
- Trial name
- NCT05049577
- Testing
- Analgesia/Nociception Index (ANI)
- Where
- South Korea
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Injection, Pain Management
Effects of Cold Spray and Buzzy Device an Pain and Fear During Penicillin Injection
This study investigates the effect of cold spray and Buzzy devices on pain and fear experienced during penicillin injections. There are three groups: a cold spray and Buzzy device, and a control group.
- Conditions
- Injection, Pain Management, Fear
- Trial name
- NCT07418021
- Testing
- Cold Spray Intervention Group, Buzy Device Intervention Group, Control Group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pain
Effect of Shotblocker and Palm Stimulator
This study discusses the advancements in nursing, particularly focusing on intramuscular injections, their complications, and innovative non-pharmacological methods such as the Shotblocker and palm stimulator to reduce pain.
- Trial name
- NCT06381804
- Testing
- shotblocker, palm stimulator
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Pain
Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Adult Patients for Pain Control During Spinal Injections (SI)
A three-group parallel randomized controlled trial to evaluate the efficacy of virtual reality analgesia (VRA) to decrease patient procedural pain and anxiety in the Adult patients undergoing Spinal Injections (SI).
- Trial name
- VR adult (NCT03787147)
- Testing
- Google Cardboard, Oculus, Lidocaine Hydrochloride
- Volunteers
- healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Pain
EXPAREL for Minimally Invasive Supracervical Hysterectomies
The aim of the of the study is a reduction in minimally invasive supracervical hysterectomy postsurgical pain, which may result in less need for supplemental opioid pain medications, fewer opioid related adverse events, and a…
- Trial name
- NCT03769714
- Testing
- Saline Solution for Injection, Exparel
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Postoperative Pain, Adverse Effects
Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week
The investigators undertook this prospective, randomized trial to compare the recovery profile throughout the first postoperative week in patients receiving continuous (CISB) interscalene brachial plexus block, single injection…
- Trial name
- NCT01881776
- Testing
- ISB
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Pain
Comparison Between the Dentapen and Vibraject
A split-mouth, controlled trial aimed to assess patient-reported pain levels during local anaesthesia administration to the buccal side of the maxillary posterior teeth using Vibraject-assisted injection and the Dentapen® system…
- Trial name
- NCT06790433
- Testing
- Vibraject, Dentapen
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Pain, Postoperative
Investigating Temporalis and Masseter Botox Injection Before Orthognathic Surgery to Improve Postoperative Pain
Jaw surgery has become a very successful way to improve the appearance and functional needs of patients. Like any surgery, jaw surgery comes with a host of possible issues that patients may experience during their recovery.
- Trial name
- NCT04794504
- Testing
- Botox 100 UNT Injection, 0.9% Saline Injection
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kingsway Oral & Maxillofacial Surgery
Injection Site Haematoma, Local Anesthetic Toxicity
U/S Guided SAPB Versus Conventional IV Analgesics in Postoperative Pain Management in MRM
The aim of this study is to compare the effect of ultra-sound guided serratus anterior plane block versus conventional IV analgesics in postoperative pain management in modified radical mastectomy (MRM)
- Trial name
- SAPB (NCT05126394)
- Testing
- ultrasound guided serratus anterior plane block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Needlestick Injuries
The Influence of Injection Speed on Pain During Administration of Local Anaesthetic.
This study will investigate the influence of injection speed on pain during injection of lidocaine. It is anticipated that a longer injection time will lead to less pain for the patient during the injection.
- Trial name
- NCT02107742
- Testing
- Normal speed lidocaine injection, Slow lidocaine injection, Fast lidocaine injection
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Migraine, Cluster Headache
Pain Biomarker Study
This study investigates molecular and physical biomarkers of headaches in order to better understand mechanisms of these diseases. There are 3 main parts: 1.
- Conditions
- Migraine, Cluster Headache, Trigeminal Autonomic Cephalgia, Hemicrania Continua
- Trial name
- PBS (NCT03511846)
- Testing
- Oral capsaicin, Topical capsaicin, Intranasal capsaicin
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Opioid Use, Surgical Recovery
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
The goal of the study to see if giving a numbing medicine around the cervix (called a paracervical block) during vaginal hysterectomy with prolapse repair helps people feel less pain and need fewer strong pain medicines…
- Conditions
- Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic
- Trial name
- NCT07213635
- Testing
- Bupivacaine-epinephrine, Normal saline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill