Clinical trials: Injections
Voice, Therapy
Voice Therapy in Reactive Benign Vocal Fold Polyp and Injection of Steroid
The aim of this study is to compare the efficacy between Voice Therapy and Injection of Steroid in Reactive Benign Vocal Fold polyp.
- Conditions
- Voice, Therapy, Vocal Fold Polyp, Steroid Injection
- Trial name
- NCT07904988
- Testing
- Group 1: Patients with reactive benign vocal fold polyp will be treated by Voice Therapy, Group 2: Patients with reactive benign vocal fold polyp will be treated by Injection of steroid
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Hernia Abdominal Wall, Botox Injection
Preoperative BOTOX® Injection for Large Ventral Hernia Repair
This study is for adults who need open surgery to repair a very large abdominal (ventral) hernia. This study tests whether a one-time, image-guided injection of a medicine commonly known as "BOTOX®" (onabotulinumtoxinA) into the…
- Conditions
- Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome
- Trial name
- PRETOX (NCT07220382)
- Testing
- OnabotulinumtoxinA Injection, OnabotulinumtoxinA, 0.9 % Normal Saline
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- The Cleveland Clinic
Pain Management, Injection Pain Prevention
Testing the Timing and Application of Virtual Reality Distraction During Knee Injections in a VA Pain Clinic
The goal of this clinical trial is to learn whether virtual reality (VR) can be added to routine knee injection appointments at a VA outpatient pain clinic without slowing down or disrupting clinic operations.
- Conditions
- Pain Management, Injection Pain Prevention, Virtual Reality, Feasibility Studies
- Trial name
- NCT07884851
- Testing
- Immersive Virtual Reality
- Volunteers
- 45 people
- Sponsor
- Atlanta VA Medical Center
No Condition, Real-time Monitoring of the Injection Pressure During Ultrasound-guided Axillary Block
Real-Time Monitoring of the Injection Pressure During the Peripheral Nerve Block
The goal of this clinical trial with medical device is to learn if the Smart Needle Monitoring System works to maintain a safe low injection pressure during a type of regional anaesthetic (Peripheral Nerve Block (PNB)) in…
- Trial name
- Smart Needle (NCT07302997)
- Testing
- Smart Needle Monitoring System
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Hepatitis C, Opioid-Related Disorders
The Kentucky Viral Hepatitis Treatment Study
The overarching goal of the Kentucky Viral Hepatitis Treatment Project (KeY Treat) is to increase hepatitis C virus (HCV) treatment access and delivery in a rural Appalachian community, which is in the midst of the…
- Conditions
- Hepatitis C, Opioid-Related Disorders, Injection Drug Use
- Trial name
- KeY Treat (NCT03949764)
- Testing
- Sofosbuvir/velpatasvir (Epclusa®)
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- Jennifer Havens
Constraint Induced Movement Therapy, Task Oriented Training
Constraint-induced Movement Therapy Versus Task-oriented Training On Upper Extremity Function Post-Botox Injection in Stroke Patients
This study will be conducted to determine the impact of Constraint-Induced Movement Therapy versus Task-Oriented Training on upper extremity function post-Botox injection in stroke patients.
- Conditions
- Constraint Induced Movement Therapy, Task Oriented Training, Botox Injection, Upper Extremity Function
- Trial name
- NCT07057050
- Testing
- The designed physiotherapy program, The Botulinum toxin injection, Task oriented training
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Cairo University
Injection Fear, Injection Pain Prevention
Does Ethyl Chloride Spray Work?
A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal…
- Conditions
- Injection Fear, Injection Pain Prevention, Injection Complication
- Trial name
- NCT06651788
- Testing
- Ethyl Chloride, Cold Saline Spray
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- University of Chicago
Injection Techniques, Nursing Interventions
Traction, Pressure, and Rapid Muscle Release (TPR) Technique During Intramuscular Injection: Effects on Pain and Patient Satisfaction
This study will be conducted to evaluate the effect of the Traction, Pressure, and Rapid Muscle Release (TPR) technique, an innovative method used during intramuscular vitamin B12 (cyanocobalamin) injections, on patients' pain…
- Conditions
- Injection Techniques, Nursing Interventions, Injection Pain Prevention, Patient Satisfaction
- Trial name
- TPRTDIMI (NCT07499687)
- Testing
- TPR Injection Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Nursing Education, Intramuscular Injection
Web-Based Gamified Simulation for Teaching Ventrogluteal Injection to First-Year Nursing Students
The goal of this study is to find out whether a web-based simulation with game features helps first-year nursing students learn how to give an injection into the muscle on the side of the hip, known as the ventrogluteal site.
- Trial name
- NCT07861750
- Testing
- Web-Based Gamified Simulation, Traditional Ventrogluteal Injection Training
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Rheumatological Injection, Pain Management
The Value of Standardized Respiratory Rate Monitoring Exercises During Rheumatological Injection Procedures
The goal of this clinical trial is to demonstrate the non-inferiority of standardized breathing control exercises on perceived pain during rheumatological injections procedures compared to standard care consisting of the addition…
- Conditions
- Rheumatological Injection, Pain Management, Respiratory Monitoring
- Trial name
- Respi-IR (NCT07172984)
- Testing
- Anesthesia, breathing group
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Injection Site Pain
The Effect of the Cold Needle Technique on Pain and Patient Satisfaction Levels During Intramuscular Injection Administered to the Ventrogluteal Site
This randomized controlled trial aims to evaluate the effect of the cold needle technique on pain and patient satisfaction during intramuscular injections administered to the ventrogluteal site.
- Trial name
- NCT07860099
- Testing
- Cold Needle Technique, Standard Intramuscular Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Bezmialem Vakif University
Arthritis, Ultrasonication
The Efficacy of Ultrasonication in Combination With Corticosteroid Intraarticular Injection for Arthritis
This study investigates whether ultrasound therapy applied prior to intra-articular corticosteroid injection can enhance the treatment efficacy for patients with joint arthritis and assess its safety.
- Conditions
- Arthritis, Ultrasonication, Intra-articular Injections, Rheumatology
- Trial name
- NCT07363876
- Testing
- Therapeutic Ultrasound, Intra-articular corticosteroid injection
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taichung Veterans General Hospital
Intraocular Inflammation, Intravitreal Injections
Real-World Incidence of Intraocular Inflammation Following Intravitreal Treatment With Aflibercept 8 mg
Aflibercept 8 mg is a high-concentration anti-vascular endothelial growth factor therapy developed to extend treatment intervals for retinal diseases while maintaining the efficacy and safety of aflibercept 2 mg.
- Trial name
- NCT07849309
- Testing
- Aflibercept (Eylea)
- Where
- Denmark
- Volunteers
- 3,690 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neovascular Age-Related Macular Degeneration (nAMD), Diabetic Macular Edema
Speculum-Free Intravitreal Injection Using Cotton-Tipped Applicator Retraction: Pain, Procedure Time, Patient Satisfaction, and Safety
This randomized controlled trial compares two techniques for eyelid retraction during intravitreal injection (IVI): an adjustable solid-blade eyelid speculum (Group A) and single-hand retraction of the upper eyelid with one…
- Conditions
- Neovascular Age-Related Macular Degeneration (nAMD), Diabetic Macular Edema, Retinal Vein Occlusion, Intravitreal Injections
- Trial name
- IVI-RETRACT (NCT07481500)
- Testing
- Eyelid Speculum Retraction, Cotton-Tipped Applicator Retraction
- Where
- Thailand
- Volunteers
- 129 people
- Sponsor
- Jakkrit Juhong
Injection Site Reaction
Prospective Study to Assess Tissue Responses After Injection With Biostimulatory Products
The objective of this study is to identify and assess in vivo tissue responses after injection with various biostimulatory products at various timepoints.
- Trial name
- NCT06093815
- Testing
- Injection
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Propofol Injection Pain in Children
Determining if the Buzzy® Personal Pain Relief Device Reduces Injection Pain of Propofol as Much as Intravenous Lidocaine in Children
Propofol is a drug commonly used for induction of general anesthesia in children as well as adults; however, propofol can cause pain on injection, possibly more frequently in children.
- Trial name
- NCT07770581
- Testing
- Buzzy device, Intravenous lidocaine
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Ventrogluteal Injection, Nursing Care
Ultrasound-Guided Assessment of Ventrogluteal Intramuscular Injection in Adults With High BMI
This study evaluated the ventrogluteal site for intramuscular injection in adults with a body mass index of 25 kg/m² or higher. Ultrasound was used to measure subcutaneous tissue, muscle, and total tissue thickness at the…
- Trial name
- NCT07827300
- Testing
- Ventrogluteal Intramuscular Injection Using a 40 mm Needle
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Marmara University
Peripheral Intravenous Phlebitis, Injection Site Pain
Ice Application for Oxacillin-Related Phlebitis and Pain
This randomized controlled trial evaluated whether ice application could reduce pain and peripheral intravenous phlebitis associated with oxacillin administration.
- Conditions
- Peripheral Intravenous Phlebitis, Injection Site Pain, Pain
- Trial name
- NCT07820956
- Testing
- Ice Application, Room-Temperature Water-Bag Application
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- Central Taiwan University of Science and Technology
Intravenous Injections, Vaccination
Efficacy of the Buzzy® Device on the Prevention of Health Care Induced Pediatric Pain in a Vaccination Center
In vaccination centers, venipunctures and vaccinations are sources of pain and anxiety in pediatric patients. Prior painful experiences can reduce the acceptance of later health care, hence making it more difficult for both…
- Trial name
- DOLVAX (NCT03220555)
- Testing
- Buzzy® device, EMLAPATCH (lidocaine, prilocaine)
- Where
- 3 sites in France
- Volunteers
- 220 people
- Sponsor
- Nantes University Hospital
Psychotic Disorder, SCHIZOPHRENIA 1 (Disorder)
Ultrasound Assessment of Gluteal Muscle in Patients Receiving Depot Antipsychotics and Healthy Volunteers
This observational study will use ultrasound to assess the gluteal musculature in patients receiving depot antipsychotic medication and in healthy volunteers.
- Conditions
- Psychotic Disorder, SCHIZOPHRENIA 1 (Disorder), Intramuscular Injection
- Trial name
- ULPSYK (NCT07815587)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital