Clinical trials: Injections
Behcet's Disease
Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation)
This investigation was conducted to obtain the following information regarding the use of Adalimumab (Humira®) 40mg Syringe 0.8mL for Subcutaneous Injection in patients with Intestinal Behcet's Disease. 1.
- Trial name
- NCT01960790
- Volunteers
- 473 people
- Sponsor
- AbbVie
Type 2 Diabetes
A Trial of INS068 in Patients With Type 2 Diabetes Not Adequately Controlled With One or Two Oral Antidiabetics
The study is being conducted to evaluate the efficacy and safety of IND068 once daily (QD) in subjects with type 2 diabetes not adequately controlled with one or two oral antidiabetics compared to insulin degludec QD for 16 weeks.
- Trial name
- NCT04663282
- Testing
- INS068 injection, Insulin Degludec
- Where
- 35 sites in United States, Australia and 1 more
- Volunteers
- 179 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Osteo Arthritis of the Knee
A Study to Evaluate Efficacy and Safety of a Single Intra-Articular Injection of HL-01 in the Treatment of Pain in Symptomatic Knee Osteoarthritis
The goal of this clinical trial is to test HL-01 in patients with knee osteoarthritis pain. The main question[s] it aims to answer are: Measure the change in average daily knee pain intensity scores from baseline to the end of…
- Trial name
- NCT07819461
- Testing
- Sodium hyaluronate solution - 3.36%, Sterile buffered solution
- Volunteers
- 704 people
- Sponsor
- IBSA Institut Biochimique SA
Nervous System Disorders
Dysport® Adult Upper Limb Spasticity
The purpose of this research study is to assess the efficacy of Dysport compared to placebo in improving muscle tone in hemiparetic subjects with upper limb spasticity due to stroke or traumatic brain injury.
- Trial name
- NCT01313299
- Testing
- Botulinum toxin type A
- Where
- 40 sites in United States, Belgium and 7 more
- Volunteers
- 243 people
- Sponsor
- Ipsen
Glabellar Lines
A Study to Evaluate AGN-151586 Intramuscular Injections in Adult Participants for Treatment of Glabellar Lines
Facial lines that develop from repeated facial expression, such as glabellar lines (GL), are typically treated by selectively weakening specific muscles with small quantities of botulinum toxin.
- Trial name
- NCT06308198
- Testing
- AGN-151586
- Where
- 12 sites in China, Japan and 1 more
- Volunteers
- 161 people
- Sponsor
- AbbVie
Psoriasis
Study of Secukinumab With 2 mL Pre-filled Syringes
The aim of the study was to demonstrate efficacy, safety and tolerability of 2 mL pre-filled syringe of 300 mg secukinumab in treatment of moderate to severe plaque psoriasis.
- Trial name
- ALLURE (NCT02748863)
- Testing
- Secukinumab 2 mL form, Secukinumab 1 mL form
- Where
- 52 sites in United States, Belgium and 9 more
- Volunteers
- 214 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Stroke
An Open-labeled Phase II Study to Evaluate the Efficacy and Safety of GXNPC-1 in Patients with Chronic Stroke
The primary objective of this study is to evaluate the efficacy for subjects with chronic stroke after GXNPC-1 injection.
- Trial name
- NCT04088149
- Testing
- GXNPC1
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Gwo Xi Stem Cell Applied Technology Co., Ltd.
Neovascular Age-related Macular Degeneration (nAMD)
Safety and Tolerability of OCU-10-C-110 for Injection in Subjects With Neovascular Age-related Macular Degeneration
Multi-center, open-label, two-part safety assessment following administration of single ascending doses and repeat administration of the HTD of OCU-10-C-110 for Injection in the study eye of participants with nAMD
- Trial name
- NCT05904691
- Testing
- OCU-10-C-110 for Injection
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Ocugenix Corporation
Respiratory Tract Infections, Urinary Tract Infections in Children
PHase IV Clinical Trial of Ceftriaxone Sodium and Sulbactam Sodium for Injection (CRO-SBT)
To evaluate the safety and efficacy of treatment of children with acute bacterial infection disease with Ceftriaxone Sodium and Sulbactam Sodium for Injection in the condition of widely used, and provide the basis of adjusting…
- Trial name
- CRO-SBT (NCT04066621)
- Testing
- Ceftriaxone Sodium and Sulbactam Sodium for Injection
- Volunteers
- 30 people
- Sponsor
- Xiangbei Welman Pharmaceutical Co., Ltd
Arthritis, Psoriatic
Evaluation of Allocetra by Intra-articular Injection for the Treatment of Psoriatic Arthritis
This is an open label study to evaluate the safety and initial efficacy of intra-articular administration of Allocetra in patients with Psoriatic Arthritis (PsA).
- Trial name
- NCT06522035
- Testing
- Allocetra
- Where
- 4 sites in Israel
- Volunteers
- 5 people
- Sponsor
- Enlivex Therapeutics Ltd.
Solid Tumor, Unspecified, Adult
The Safety and Dosimetry Study of 177Lu-LNC1004 Injection
This proposal is a phase I, open-label study of a 4-Dose Regimen of Escalating Doses of 177Lu-LNC1004 Injection in patients with recurrent or metastatic, fibroblast activation protein-positive solid tumors.
- Trial name
- NCT05723640
- Testing
- 177Lu-LNC1004 Injection group 1 radionuclide therapy, 177Lu-LNC1004 Injection group 2 radionuclide therapy, 177Lu-LNC1004 Injection group 3 radionuclide therapy
- Where
- Singapore
- Volunteers
- 11 people
- Sponsor
- Yantai LNC Biotechnology Singapore PTE. LTD.
Parathyroid Hormone
Study of Zemplar iv in Patients With End Stage Chronic Kidney Disease, Undergoing Haemodialysis
This is the post-marketing study conducted in two countries: Croatia and Serbia. In both countries Zemplar (paricalcitol) is the first injectable form of any Vitamin D Receptor (VDR) activator available for chronic kidney disease…
- Trial name
- NCT01084538
- Testing
- Zemplar iv (paricalcitol iv)
- Where
- 21 sites in Croatia, Serbia
- Volunteers
- 181 people
- Sponsor
- Abbott
Macular Degeneration
Extension Study of rhuFab V2 in Subjects With Neovascular Age-Related Macular Degeneration (AMD)
This is a Phase III, open-label, multicenter extension study of intravitreally administered ranibizumab in subjects with primary or recurrent subfoveal choroidal neovascularization (CNV) secondary to AMD who have completed the…
- Trial name
- NCT00095433
- Testing
- rhuFab V2 (ranibizumab)
- Volunteers
- 100 people
- Sponsor
- Genentech, Inc.
Nasolabial Folds
Evaluate Efficacy, Safety & Subject Satisfaction of Pain Management With Pliaglis® Cream for Dermal Filler Injections
Pliaglis® Cream versus compounded topical anesthetic for pain management during Restylane® injections for the correction of nasolabial folds.
- Trial name
- NCT00716443
- Testing
- tetracaine 7% / lidocaine 7% cream (Pliaglis® Cream), benzocaine 20% / lidocaine 6% / tetracaine 4% ointment
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Galderma R&D
Knee Osteoarthritis
sAfety PerfoRmance chitOsan osteOarthritis ViscosupplEmentation
KIO014 is an innovative chitosan-based biomaterial intended for synovial fluid viscosupplementation indicated for the symptomatic treatment of knee osteoarthritis (OA).
- Trial name
- APROOVE (NCT03679208)
- Testing
- Investigational device coded KIO014, Durolane(r) as control device
- Volunteers
- 100 people
- Sponsor
- Kiomed Pharma
HIV Infections
QUALITE Study - A Study of Fuzeon (Enfuvirtide) in Treatment-Experienced Patients With Human Immunodeficiency Virus-1 (HIV-1) Infection
This study will evaluate patient quality of life and tolerability of a HAART (highly active antiretroviral therapy) regimen containing twice-daily subcutaneous injections of Fuzeon in clinically stable, treatment-experienced…
- Trial name
- NCT00232908
- Testing
- ARV regimen, enfuvirtide [Fuzeon]
- Where
- 106 sites in United States, Puerto Rico
- Volunteers
- 361 people
- Sponsor
- Hoffmann-La Roche
Adolescent Asthma
Pharmacokinetics, Pharmacodynamics, Safety, and Preliminary Efficacy of Subcutaneous Injection of SHR-1905 in Adolescent Asthmatic Subjects - an Open-label, Single-dose Phase II Clinical Study
Pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy of subcutaneous injection of SHR-1905 in adolescent asthmatic subjects - an open-label, single-dose Phase II clinical study
- Trial name
- NCT06786455
- Testing
- SHR-1905 Injection
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Guangdong Hengrui Pharmaceutical Co., Ltd
Healthy Subjects
A Study of GZR4 Injection at Different Injection Sites
This trial is conducted in China. This study is a randomized, single-center, open, three-period crossover trial in healthy subjects to compare the PK, PD, and safety of a single administration of GZR4 at different injection sites…
- Trial name
- NCT06548906
- Testing
- GZR4 Injection
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Advanced Hepatocellular Carcinoma (HCC)
A Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepatocellular Carcinoma (HCC)
This is a randomized, controlled, open-label, multicenter study to evaluate efficacy of AK105 injection combined with Anlotinib Hydrochloride Capsules versus Sorafenib.
- Trial name
- NCT04344158
- Testing
- AK105 Injection, Anlotinib Hydrochloride Capsules, Sorafenib Tosylate Tablets
- Where
- 81 sites in China
- Volunteers
- 648 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Solid Tumor Malignancies
GKL-006Allo Injection in Patients With Advanced Solid Tumors
This is a Phase 1 study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary anti-tumor activity of GKL-006Allo Injection in participants with advanced solid tumors.
- Trial name
- NCT07704515
- Testing
- GKL-006Allo Injection
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Beijing Gene Key Life Technology Co., Ltd
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