Clinical trials: Injections
Injection Site Pain, Pain
Comparing Pre-Anesthetic Approaches in Dentistry
The main purpose of this study is to find out which pre-treatment method works best to reduce pain from dental anesthesia injections in adult patients.
- Trial name
- NCT07703553
- Testing
- 10% lidocaine spray, Ice Pen (Cryotherapy)
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Harran University
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Low Back Pain (LBP), Lumbar Radiculopathy
The Effect of Needle Insertion Angle on Contrast Distribution and Treatment Outcomes in S1 Transforaminal Epidural Steroid Injections
Nerve compression due to lumbar disc herniation (lumbosacral radiculopathy) is a condition characterized by pain in the lower back and legs and restricted lumbar joint movement due to the compression of nerves emerging from the…
- Conditions
- Low Back Pain (LBP), Lumbar Radiculopathy, Intravascular Injection
- Trial name
- Transforaminal (NCT06801990)
- Testing
- S1 transforaminal epidural steroid(dexamethasone) injection
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Marmara University
Simulation Training, Midwifery Education
Simulation-Based Subcutaneous Injection Training in Midwifery Students
The goal of this clinical trial is to compare three simulation-based approaches for teaching subcutaneous injections to first-year midwifery students.
- Conditions
- Simulation Training, Midwifery Education, Subcutaneous Injection
- Trial name
- NCT07793188
- Testing
- Mannequin-Based Subcutaneous Injection Training, Peer-Based Subcutaneous Injection Training, Self-Based Subcutaneous Injection Training
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ankara University
Type 2 Diabetes Mellitus (T2DM), Pain
Effects of Self-Selected Music on Self-Injection Fear, Blood Glucose Testing Fear, and Pain
Fear and pain associated with self-insulin injection and blood glucose self-testing may negatively affect diabetes self-management.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Pain, Fear of Injections
- Trial name
- NCT06790550
- Testing
- Self-Selected Music Listening
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dicle University
Propofol Injection Pain
Arm Elevation for Prevention of Propofol Injection Pain
The purpose of this research is to determine whether a simple technique, temporarily raising the arm during the injection of propofol (a commonly used medication for anesthesia), can reduce the pain that some people experience…
- Trial name
- NCT07785674
- Testing
- Passive arm elevation, Normal saline, Lidocaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Procedural Pain, Vaccination Pain
Cold Spray and Helfer Skin Tap for Pain During Infant Vaccination
This randomized controlled experimental study aims to evaluate the effects of cold spray and the Helfer Skin Tap technique on pain levels during intramuscular pneumococcal conjugate vaccine administration in 12-month-old infants.
- Conditions
- Procedural Pain, Vaccination Pain, Injection Pain
- Trial name
- NCT07779681
- Testing
- Cold spray, Helfer Skin Tap Technique
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hitit University
Knee Arthritis Osteoarthritis, Platelet Rich Plasma Injection
Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS)
The effects of single dose injection of platelet rich plasma or conditioned serum in the knee joint in patients with knee osteoarthritis will be compared
- Conditions
- Knee Arthritis Osteoarthritis, Platelet Rich Plasma Injection, Conditioned Serum
- Trial name
- KOA PRP ACS (NCT07473232)
- Testing
- Autologous Platelet-Rich Plasma (PRP), Conditioned serum (CS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Knee Osteoarthristis, Cartilage Damage
Pilot Exploration of Platelet Characterization of Platelet Rich Plasma Created by Two Different Systems
The investigators would like to study the differences in the quality of Platelet Rich Plasma (PRP) between two different machines in those with knee osteoarthritis.
- Conditions
- Knee Osteoarthristis, Cartilage Damage, Platelet Rich Plasma, Platelet Rich Plasma Injection
- Trial name
- PRP-PEPC (NCT07491367)
- Testing
- Platelet Rich Plasma, Emcyte PurePRP Supraphysiologic Concentrating System, APEX Biologix XCELL PRP System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse
Efficacy of Platelet Rich Plasma on Pelvic Floor Muscle Strength and Recurrence Rate in Pelvic Organ Prolapse Surgery
Pelvic organ prolapse (POP) is a common pelvic floor disorder associated with impaired quality of life and considerable postoperative recurrence following native tissue repair.
- Conditions
- Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse, Platelet Rich Plasma Injection
- Trial name
- NCT07746739
- Testing
- POP surgery adjunctive PRP
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Andalas University
Children, Pain Management
Effect of Vibration and ShotBlocker on Pain and Fear Levels During Intramuscular Injection in Children in the Emergency Department
This prospective study is planned as a randomized controlled study. The aim of this study is to investigate the effects of vibration and the ShotBlocker method on pain and fear levels in children during intramuscular injection in…
- Conditions
- Children, Pain Management, Vibration, Shotblocker
- Trial name
- NCT07750626
- Testing
- Vibration, Shotblocker
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Burdur Mehmet Akif Ersoy University
Frozen Shoulder, Chronic Pain
Comparison of Transcatheter Arterial Microembolization and Corticosteroid Injection and for Treatment of Frozen Shoulder
Objectives： This study aims to compare the efficacy of transcatheter arterial microembolization (TAME) and corticosteroid injection for treatment of frozen shoulder.
- Conditions
- Frozen Shoulder, Chronic Pain, Adhesive Capsulitis, Transcatheter Arterial Microembolization
- Trial name
- NCT07696923
- Testing
- TAME group, CS injection group
- Where
- Taiwan
- Volunteers
- 94 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Intra-Prostatic Epinephrine Injection in Bipolar Transurethral Resection of Large Prostate
Intra-Prostatic Epinephrine Injection in Bipolar Transurethral Resection of Large Prostate: Exploring Its Role in Optimizing Surgical Outcomes
Intra-Prostatic Epinephrine injection in Bipolar Transurethral resection of large prostate: Exploring Its Role in Optimizing Surgical Outcomes
- Trial name
- NCT07733167
- Testing
- TURP, Epinephrine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Pelvic Organ Prolapse Vaginal Surgery, Platelet Rich Plasma Injection
The Effects of Platelet Rich Plasma Adjuvant to Type I/III Collagen Ratio, Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Pelvic Organ Prolapse Repair
The goal of this clinical trial is to analyze the effect of Platelet Rich Plasma (PRP) Adjuvant To Type I/III Colagen Ratio, MMP-2 and MMP-9 in Pelvic Organ Prolapse Repair.
- Trial name
- POP PRP MMP (NCT07150442)
- Testing
- POP surgery and PRP injection
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Andalas University
Effect of Patient Awareness on Incidence and Severity of Propofol Injection Induced Pain
Effect Of Patient Awareness About Possibility Of Occurrence Of Pain During Propofol Injection On The Rate Of Incidence And Severity Of Pain During Injection .
Propofol is the most common intravenous (IV) anesthetic agent, used for anesthesia induction and maintenance during surgeries due to its rapid onset and short duration.
- Trial name
- No acronym (NCT05886972)
- Testing
- Awareness about propofol injection induced pain
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Facial Filler Injections, Hyaluronic Acid
Effect of TXA on Reducing Bruising After Filler Injection
The goal of this clinical trial is to look at the effect tranexamic acid (TXA) may have on reducing bruising, swelling, and pain after facial filler injection.
- Conditions
- Facial Filler Injections, Hyaluronic Acid, Tranexamic Acid
- Trial name
- NCT06665594
- Testing
- Hyaluronic Acid (HA), Tranexamic Acid (TXA)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Endophthalmitis, Endophthalmitis Postoperative
Phacovitrectomy Versus Pars Plana Vitrectomy Alone for Post-Intravitreal Injection Endophthalmitis
This prospective comparative interventional study evaluated the anatomical and visual outcomes of phacovitrectomy versus pars plana vitrectomy (PPV) alone in patients with post-intravitreal injection endophthalmitis.
- Conditions
- Endophthalmitis, Endophthalmitis Postoperative, Intravitreal Injection Patients
- Trial name
- NCT07717944
- Testing
- Phacovitrectomy, Pars plana vitrectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Adhesive Capsulitis, Corticosteroid Injection
Pericapsular vs Intra-Articular Injection in Adhesive Capsulitis
Adhesive capsulitis is a common and disabling shoulder disorder characterized by progressive pain and restricted active and passive range of motion, leading to significant limitations in daily activities and reduced quality of…
- Trial name
- NCT07710651
- Testing
- Betamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Overactive Bladder (OAB), Botulinum Toxin Injection
Pretibial TENS for Pain and Anxiety During Intravesical OnabotulinumtoxinA Injection
Overactive bladder is a common condition that causes a frequent, urgent need to urinate and can significantly reduce quality of life.
- Conditions
- Overactive Bladder (OAB), Botulinum Toxin Injection, Procedural Pain Relief, Anxiety
- Trial name
- NCT07707791
- Testing
- Active Pretibial TENS
- Volunteers
- 68 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Video-assisted Thoracoscopic Surgery (VATS), Pain Management
The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy. It is reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Pain Management, Liposomal Bupivacaine, Local Injection
- Trial name
- NCT07432711
- Testing
- Bupivacaine hydrochloride, Liposomal bupivacaine plus bupivacaine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Tiantan Hospital