Clinical trials: Injuries, Knee
Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
The purpose of this randomized clinical trial is to determine the difference in quality of life outcome at two years, in patients undergoing an Anterior Cruciate Ligament (ACL) reconstruction procedure with either a patellar…
- Conditions
- Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament, Chronic Instability of Knee, Anterior Cruciate Ligament Injury
- Trial name
- NCT00529958
- Testing
- Patellar Tendon, Hamstring Tendon, Double-Bundle
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Wound of Skin, Non-melanoma Skin Cancer
Efficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical Defects
Large full-thickness skin defects, such as those resulting from trauma, large and giant congenital nevi, disfiguring scars, or tumor resection remain major clinical problems to patients and physicians.
- Conditions
- Wound of Skin, Non-melanoma Skin Cancer, Skin Graft Complications, Wound of Lower Leg
- Trial name
- NCT03548610
- Testing
- Nanofat-seeded biological scaffold on surgical defect
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Anterior Cruciate Ligament Injuries
Biologic Therapy to Prevent Osteoarthritis After ACL Injury
Anterior cruciate ligament (ACL) injuries are extremely common. On average, 50% of individuals suffering an ACL injury will develop radiographic osteoarthritis (OA) 10 to 20 years after injury.
- Trial name
- NCT03968913
- Testing
- Anakinra injection, sterile saline injection
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anterior Cruciate Ligament Injury, Muscle Weakness
WEakness and Atrophy: isoKinetic With Surface Electromyography Assessment in ACL Surgery
An assessment of the effect of surgical anterior cruciate ligament (ACL) on thigh muscles is critical to the improvement of knee rehabilitation and preservation.
- Trial name
- WEAKNESS (NCT03200678)
- Testing
- isokinetic assessment
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Lower Limb Amputation Knee, Lower Limb Amputation Below Knee (Injury)
Validity and Reliability of The 3-Meter Backward Walk Test in Individuals With Lower Limb Amputation
Clinicians are routinely required to make decisions about fall risk among lower limb prosthesis users. For these decisions, clinicians should use valid, reliable, quantitative, and multidimensional measures of balance test for…
- Trial name
- NCT05095584
- Testing
- 3 meter backward walk test
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tezel Yıldırım Şahan
Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee
Post-Traumatic Knee Osteoarthritis Following Anterior Cruciate Ligament Reconstruction
The purpose of this trial is to define knee joint pathomechanics (KJPM) in the first 2 years after ACL reconstruction (ACLR) and relate these KJPM with changes in articular cartilage morphology and quality.
- Trial name
- NCT06201442
- Testing
- Imaging - magnetic resonance imaging (MRI), Blood sampling, Assessment of functionality and strength
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sports Injury, Anterior Cruciate Ligament Rupture
Comparison of Functional Outcome Between BQT and SBHT ACL Reconstruction
ACL rupture has a high morbidity in productive-age population. The increasing incidence and proper management has become a point of interest in the musculoskeletal sport injury.
- Trial name
- BQTSBHTFMUI (NCT04536246)
- Testing
- Bone Quadriceps Tendon (BQT) arthroscopic-assisted ACL reconstruction, Single-Bundle Hamstring Tendon (SBHT) arthroscopic-assisted ACL reconstruction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Dynamic Knee Valgus, Injury Prevention
Progressive Resistance Training Compared to Neuromuscular Exercises on Knee Kinematics
The primary aim of this randomized controlled trial is to investigate the effectiveness of 6 weeks of progressive resistance training (PRT) compared to neuromuscular training (NMT) on functional performance in healthy female…
- Trial name
- NCT05695482
- Testing
- Neuromuscular training exercises, Hip abductors muscular strength exercises
- Where
- Greece
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Anterior Cruciate Ligament Rupture
Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
The Investigators are studying the effect of an ACL reconstruction on return to play by capturing outcome measures and biomechanics information.
- Trial name
- NCT06294314
- Testing
- Fertilized ACL
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marshall University
ACL Injury
Neuroplasticity Associated With Anterior Cruciate Ligament Injury
Activation of the brain for knee movement changes after anterior cruciate ligament (ACL) reconstruction. The brain activation profile after ACL reconstruction indicates a shift to a visual-motor control strategy, as opposed to a…
- Trial name
- NCT03654495
- Testing
- Exergame training, Usual Care Training
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Defect of Articular Cartilage, Articular Cartilage Disorder of Knee
the Safety and Efficacy Evaluation of Chondron Compared With Mircrofracture of Knee
The purpose of this study is to evaluate safety and efficacy of Chondron(autologous cultured Chondrocyte) by comparing between Chondron implantation and Microfracture.
- Conditions
- Defect of Articular Cartilage, Articular Cartilage Disorder of Knee, Degeneration; Articular Cartilage, Knee
- Trial name
- NCT02524509
- Where
- South Korea
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Lower Limb Amputation Above Knee (Injury)
The CYBERnetic LowEr Imb coGnitive Ortho-prostheis Plus Plus, 2nd Clinical Study (CLs++)
The aim of the project is to evaluate the efficacy of the Cyberlegs X-leg in people with a unilateral transfemoral (above the knee joint) and transtibial (under the knee joint) amputation.
- Trial name
- NCT04129853
- Testing
- Cyberlegs Xleg
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Knee Injuries, Knee Arthritis
Kinematic Parameters to Predict Knee Diseases.
There is no study to explore the prediction of knee diseases using kinematic parameters of knee during gait. The aim of this study is to explore the possibility of predicting knee diseases by gait parameters.
- Trial name
- NCT03130400
- Testing
- Observational gait analysis procedure
- Where
- China
- Volunteers
- 1,914 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
ACL Injury
Neuromuscular Training Improves Single-Limb Stability
Pretest/post-test study design, study will try to determine if a 6-week neuromuscular training program designed to decrease the incidence of anterior cruciate ligament (ACL) injuries would improve single-limb stability in young…
- Trial name
- NCT04967937
- Testing
- Strengthening, resistance exercise, plyometric and dynamic movement training
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Lower Limb Amputation Above Knee (Injury)
Evaluation of a Motorised Prosthetic Knee
The study will investigate the effect over time of the Power Knee (Össur) on performance during daily activities in people with a unilateral transfemoral amputation, will determine subjective feelings and gait kinematics over…
- Trial name
- MOKI-B (NCT05407545)
- Testing
- Current prosthesis, Active Prosthesis (PowerKnee)
- Where
- Belgium
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Core Strength, Knee Stability
Influence of Abdominal Muscle Function on Knee Stability for Injury Prevention
The goal of this clinical trial is to learn whether an 8-week core stabilization training program can improve abdominal strength and knee stability in physically active women aged 18 to 35.
- Trial name
- NCT07499973
- Testing
- Core Stabilization Training Program
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- European University of Madrid
Arthropathy of Knee, Osteo Arthritis Knee
Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Replacement
The main purpose of this study is to look at whether meditation techniques can help reduce pain and opioid use after surgery.
- Conditions
- Arthropathy of Knee, Osteo Arthritis Knee, Osteonecrosis, Meditation
- Trial name
- NCT05669066
- Testing
- Mindful meditation
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Hallux Valgus
The Effect of Hallux Valgus Angle on Dynamic Knee Movement Pattern
Abstract Background/aim: Little is known about the relationship between hallux valgus and the alignment of proximal joints. Dynamic knee valgus is a movement pattern characterized by excessive knee abduction along with femoral…
- Trial name
- NCT06563037
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Total Knee Replacement
Biochemical Approach to Measuring Surgical Trauma
This study will examine the magnitude and time course of changes in circulating (serum and plasma) biomarker concentrations associated with musculoskeletal injury created by total knee replacement surgery.
- Trial name
- NCT01037400
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Patella Dislocation Recurrent, Patellar Dislocation
Clinical Outcomes Following Patellar Dislocation in Young Athletes
The purpose of this study is to identify predictors of future injury and disability following LPD. The investigators' long term goal is to improve longitudinal outcomes of athletes with LPD following surgical and non-surgical…
- Trial name
- NCT03040232
- Testing
- biomechanical assessment
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati