Clinical trials: Injuries, Knee
Knee Injury
Electromyostimulation and Strength Walking for Knee Injuries
The purpose of this project is to compare three treatment regimens for knee injury to the standard rehabilitation protocol: 1) NMES, 2) graduated strength walking (via a weighted vest), and 3) NMES combined with graduated…
- Trial name
- KI (NCT02065518)
- Testing
- NMES, Strength Walking, Standard Rehabilitation Protocol
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- University of Tennessee
Traumatic Cartilage Injury
Treating Patients With Traumatic Chondral Lesions With Autologous Bone Marrow Cells Derived Engineered Tissues - Engineered Osteochondral Tissue
The objective of the study is to establish the safety profile of the autologous engineered osteochondral tissues (eOCT) in treating traumatic chondral lesions in patients.
- Trial name
- TCL-aMSC-eOCT (NCT06400862)
- Testing
- eOCT implantation
- Where
- 2 sites in Hong Kong
- Volunteers
- 4 people
- Sponsor
- Chinese University of Hong Kong
Spine Degeneration, Hip Arthritis
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
This study aims to evaluate the effectiveness of a mobile application in improving postoperative rehabilitation outcomes among patients undergoing orthopedic surgery.
- Conditions
- Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
- Trial name
- NCT06407427
- Testing
- App for in-bed conditioning exercises, Usual care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Focal Cartilage Lesions of the Knee
Management of Focal Cartilage Lesions of the Knee: The Benefits of an Autograft Procedure
Cartilage is a tissue whose primary function is to transmit and distribute loads when joints are under stress. It acts as a buffer between bones at the joints.
- Trial name
- CART-MCI Knee (NCT07641868)
- Testing
- Management of focal cartilage lesions of the knee: micro-fracture, Minced Cartilage Implantation (MCI)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Louis Pasteur Santé Lorraine
Rupture of Anterior Cruciate Ligament
The Effect of Early WBVT on Neuromuscular Control After ACLR
To investigate the effect of early WBVT on neuromuscular control after ACLR.
- Trial name
- WBVT (NCT01300182)
- Testing
- Whole body vibration therapy, Control
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis, Pain
Patellar Resurfacing in Total Knee Arthroplasty
Background: The best treatment of the patella during total knee arthroplasty (TKA) is controversial. The implantation of a patellar component adds to the operation time and the costs of the operation.There is a huge variation as…
- Trial name
- NCT00553982
- Testing
- Patellar component, No patellar component
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Sykehuset Innlandet HF
Musculoskeletal Pain, Musculoskeletal Injury
The Diagnostic Accuracy of the Clinical Examination
This study examines the diagnostic accuracy of the clinical examination as compared to MRI findings
- Trial name
- NCT03850470
- Testing
- clinical examination, MRI
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- High Point University
ACL Injury, Kinesiotape
Kinesio Taping for the Knee and Ankle: Acute Impact on Balance, Proprioception, and ACL Risk
This study aims to evaluate and compare the acute effects of Kinesio taping applied to the knee and ankle on balance, proprioception, and anterior cruciate ligament (ACL) injury risk using the Landing Error Scoring System (LESS).
- Conditions
- ACL Injury, Kinesiotape, Balance, Proprioception
- Trial name
- ACL (NCT07138573)
- Testing
- Kinesio Taping (KT) applied to the knee then ankle, Kinesio Taping (KT) applied to the ankle then knee
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Knee Injuries, Pain Syndrome
The Effect of Kinesio Taping® on Motor Control in Patients With Patellofemoral Pain Syndrome
Background: Recently, several professionals are using the Kinesio Taping® in the treatment of pathologies related to the knee, aiming to improve the motor control, increase the response of muscle activation and promoting better…
- Trial name
- NCT03117205
- Testing
- Application of Kinesio Taping®
- Volunteers
- 40 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Tibial Meniscus Injuries, Osteoarthritis, Knee
Autologous, Micro-fragmented Adipose Tissue for Meniscal Tears
The menisci of the knee are essential fibro-cartilaginous structures that contribute in static weight bearing, distributing compressive forces during joint movement, joint lubrication, joint stabilization, and proprioception.
- Trial name
- NCT03714659
- Testing
- Lipogems
- Volunteers
- 20 people
- Sponsor
- New Jersey Regenerative Institute, LLC
Hip Arthritis, Sarcopenia
Effects of Whey and Collagen on FFM, Muscle Strength and Wound Healing in Elderly Surgical Patients
The purpose of the study is to compare the effect of whey protein and collagen on fat free mass, muscle strength, functional ability, wound healing and life quality in elderly patients undergoing elective knee- or hip surgery…
- Conditions
- Hip Arthritis, Sarcopenia, Knee Arthritis
- Trial name
- NCT04496856
- Testing
- Whey protein and Collagen supplementation
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Copenhagen
Knee Osteoarthritis
Hydrolyzed Collagen Formulation vs Placebo in Knee Osteoarthritis
The aim of the study is to compare the 6 months clinical outcome of the treatment with a single intra-articular collagen injection versus a single placebo (saline solution) infiltration in the infiltrative treatment of knee…
- Trial name
- NCT04998188
- Testing
- Collagen
- Where
- Italy
- Volunteers
- 204 people
- Sponsor
- Istituto Ortopedico Rizzoli
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Total Hip Replacement, Total Knee Replacement
Dressing-related Experiences and Surgical Site Self-care in Hip and Knee Replacement: an Observational Cohort Study
The goal of this prospective observational cohort study is to investigate dressing-related experiences and surgical site self-care in patients who are undergoing a total hip or knee replacement.
- Trial name
- DRESS-X (NCT07471243)
- Testing
- Wound Dressing Material
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Bournemouth University
Anterior Cruciate Ligament Tear, Medial Collateral Ligament
A Study to Evaluate the Incrediwear Products Immediately After ACL Repair
To assess the benefits of using the Incrediwear knee products after ACL or ACL+MCL arthroscopic surgery, on the postoperative pain, range of motion and effusion.
- Trial name
- NCT06668376
- Testing
- Leg Sleeve
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Texas Bone and Joint
Anterior Cruciate Ligament Rupture
Evaluation of Tibial and Femoral Tunnel Position After Arthroscopic Reconstruction of the Anterior Cruciate Ligament
The purpose of this study is to evaluate the accuracy of tunnel positions in anterior cruciate ligament reconstruction
- Trial name
- NCT01267435
- Testing
- Anterior cruciate ligament reconstruction
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Tendinopathy
Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich Plasma
Platelet rich plasma has been used in previous studies to stimulate faster healing of torn ligaments and tendons in order to help reduce pain and restore normal function.
- Trial name
- NCT01406821
- Testing
- Ultrasound-guided platelet-rich-plasma (PRP) injection, Ultrasound-guided dry needling
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Femoral Shaft Fractures and Patellar Fractures, Knee Fractures
Development and Clinical Evaluation of a Novel Hollow Cusp Fracture Reducer for Femoral Shaft and Patellar Fractures
This study aimed to develop and clinically evaluate a novel hollow cusp fracture reducer for enhancing the precision and efficiency of closed reduction and internal fixation in patients with femoral shaft fractures and patellar…
- Conditions
- Femoral Shaft Fractures and Patellar Fractures, Knee Fractures, Femoral Fractures
- Trial name
- NCT07534904
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Hanzhong Central Hospital
Articular Cartilage Disorder of Knee, Articular Cartilage; Degeneration
Efficacy and Safety Study of Intra-Articular Injections of Autologous Peripheral Blood Stem Cells Following Subchondral Drilling Surgery for the Treatment of Articular Cartilage Injury in the Knee
This is a 24-month, multicenter, randomized, open-label, standard treatment-controlled, parallel-group, Phase 2 study for adults with large or complicated knee articular cartilage lesions and are candidates for knee joint…
- Trial name
- NCT03101163
- Testing
- Autologous peripheral blood stem cells and hyaluronic acid, Hyaluronic acid
- Where
- 2 sites in United States, Malaysia
- Volunteers
- 120 people
- Sponsor
- KLSMC Stem Cells, Inc.
Knee Osteoarthritis (Knee OA)
Comparison of SVF Injection With and Without Microfracture in Moderate Knee Osteoarthritis
This prospective, randomized controlled clinical trial aims to evaluate the clinical and radiological effects of combining stromal vascular fraction (SVF) therapy with arthroscopic microfracture in patients with knee…
- Trial name
- NCT07112885
- Testing
- Arthroscopic Microfracture Combined with Autologous SVF Injection, Arthroscopic Debridement Followed by Autologous SVF Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
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