Clinical trials: Injuries, Knee
Knee Arthroscopy, Acute Pain
"Comparison of Intra-articular of 0.2% Ropivacaine vs. 0.75% Ropivacaine in Postoperative of Knee Arthroscopy"
All patients with acute lesions that attend the orthopedic and trauma center of the ABC medical center are invited to participate in the study.
- Trial name
- ropivacaine (NCT05807945)
- Testing
- Ropivacaine 0.75% Injectable Solution, Ropivacaine 0.2% Injectable Solution
- Where
- Mexico
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Paola M Zamora Munoz
Muscle Weakness, Anterior Cruciate Ligament Rupture
Does Gabapentin Reduce Quadriceps Muscle Weakness After Anterior Cruciate Ligament Reconstruction?
Anterior cruciate ligament (ACL) injury is a common sport injury in both professional and recreational athletes. Furthermore, persistent quadriceps weakness and wasting are frequently observed after anterior cruciate ligament…
- Trial name
- NCT03496389
- Testing
- Gabapentin, Tramadol, Panadol
- Volunteers
- 30 people
- Sponsor
- Hospital Authority, Hong Kong
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Physical Activity, Knee Joint Loading and Joint Health
The purpose of this study is to investigate the association between time spent in moderate to vigorous physical activity and markers of cartilage metabolism in the years following anterior cruciate ligament reconstruction.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Post-traumatic Osteoarthritis
- Trial name
- NCT05306054
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Bath
Anterior Cruciate Ligament Rupture
The Effect of Subtalar Joint Antipronation Taping on the Dynamic Knee Valgus in Female Volleyball Players with Low Medial Arch
This study aims to investigate the biomechanical mechanisms of dynamic knee valgus and the impact of subtalar pronation, particularly due to decreased medial longitudinal arch, on knee injury risk, highlighting the importance of…
- Trial name
- NCT06752109
- Testing
- Antipronation Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara Yildirim Beyazıt University
Bone Fracture
HealthEast Community Hip and Knee Replacement Registry
HealthEast Care System began the first community-based joint replacement registry (HJRR) in the U.S. in 1991, and now has more than 30,000 total joints registered.
- Trial name
- HEJR (NCT02692092)
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- HealthEast Care System
Osteoarthritis, Knee, Arthritis, Rheumatoid
Evaluation of Medium Cross-linked Polyethylene With and Without Vitamin E for Total Knee Arthroplasty
Prospective, randomized, single-blind, multinational, long-term study for the evaluation of the clinical outcome, oxidation profile and wear analysis of medium cross-linked Polyethylene with and without Vitamin E for total knee…
- Conditions
- Osteoarthritis, Knee, Arthritis, Rheumatoid, Intra-Articular Fractures, Joint Instability
- Trial name
- VIKEP (NCT04618016)
- Testing
- UHMWPE with Vitamin E, UHMWPE without Vitamin E
- Where
- 8 sites in France, Germany
- Volunteers
- 605 people
- Sponsor
- Aesculap AG
Healthy
Biomechanics Responses to Power and Strength Combined Training
Anterior cruciate ligament (ACL) is the most frequently injured knee ligament during performance of recreational activities and sports.
- Trial name
- NCT04139187
- Testing
- Combined training with power and strength exercises
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Patellar Dislocation
Comparison of Two Graft Choices in Mediale Patellofemoral Ligament Reconstruction (MPFL)
The purpose of this study is to elucidate surgical techniques for reconstructing MPFL in the treatment of chronic patella instability.
- Trial name
- NCT05706363
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Sprain, Strain
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Imprimis Pharmaceuticals is investigating a proprietary, topical cream formulation consisting of 10% ketoprofen (containing 100 mg of ketoprofen in 1gram of cream) for the local treatment of acute musculoskeletal pain.
- Conditions
- Sprain, Strain, Acute Soft Tissue Injury
- Trial name
- NCT00765700
- Testing
- Topical Ketoprofen 10% Cream
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- Imprimis Pharmaceuticals, Inc.
Knee Arthroplasty
First Mobilization Protocol for Total Knee Arthroplasty Patients
This single blinded randomized controlled study evaluates the effect of developed First Mobilization Protocol applied to knee arthroplasty patients on state anxiety, kinesiophobia, initial mobilization related symptoms.
- Trial name
- NCT06268899
- Testing
- First mobilization protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cruciate Ligament Reconstruction, Cruciate Ligament Rupture
Biological Potentials in Arthroscopic All-inside Semitendinosus Anterior Cruciate Ligament Reconstruction
A randomized, double-blind, prospective single-center clinical trial evaluating the effect of biological augmentation in anterior cruciate ligament (ACL) reconstruction.
- Conditions
- Cruciate Ligament Reconstruction, Cruciate Ligament Rupture, Cruciate Ligament Injury
- Trial name
- BioACL (NCT07506304)
- Testing
- ACL reconstruction
- Volunteers
- 70 people
- Sponsor
- University Hospital Dubrava
Thrombosis, Venous
A Study to Evaluate the Efficacy and Safety of Fondaparinux for the Prevention of Venous Blood Clots in Patients With a Plaster Cast or Other Type of Immobilization for a Below-knee Injury Not Needing Surgery
The purpose of this study is to evaluate the efficacy and safety of fondaparinux in comparison with a heparin (nadroparin) in preventing deep vein thrombosis (blood clots in the leg veins), whether symptomatic or detected by…
- Trial name
- FONDACAST (NCT00843492)
- Testing
- Fondaparinux sodium, Nadroparin
- Where
- 122 sites in France, Germany and 4 more
- Volunteers
- 1,351 people
- Sponsor
- GlaxoSmithKline
Knee Osteoarthritis
Effects of MWM Vs Sustained Mobilization on Knee Osteoarthritis
This article focused on people diagnosed with grade III Knee OA with sample size of 68 patients , who will randomly divided into two groups .
- Trial name
- MWM (NCT07315464)
- Testing
- mulligan moblization, kaltenborn moblization
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Injury, Knee, Injury, Ankle
Prevention of Patellar and Achilles Tendinopathies in Youth Basketball
This study seeks to determine the prevalence of knee and ankle tendinopathies in youth basketball players, as well as determine the efficacy of a Basketball specific Neuromuscular training warm-up in reducing injuries.
- Conditions
- Injury, Knee, Injury, Ankle, Tendinopathy, Sports Injuries in Children
- Trial name
- NCT04363398
- Testing
- Comprehensive Follow-up, Standard Follow-up
- Where
- Canada
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Sport Injury Prevention Research Centre
Stroke, Traumatic Brain Injury
Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention
The aging population and its accompanying burden from non-communicable chronic diseases predicts an increasing impact imposed by frailty on healthcare systems.
- Conditions
- Stroke, Traumatic Brain Injury, Knee Osteoarthritis, Breast Cancer
- Trial name
- OPTIMA-C (NCT06073106)
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Tan Tock Seng Hospital
Knee Injuries
Comparison of Different Treatment Methods in Patella Chondromalacia
Chondromalacia patella (CMP) is a common condition in patients presenting to healthcare units with anterior knee pain (1).
- Trial name
- NCT06420882
- Testing
- The experimental group., The home exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Strength, Exercise
Impact of Pilates on Running Mechanics
INTRODUCTION: Core strengthening, balance, and flexibility programs such as Pilates have been advocated to affect running mechanics and prevent lower extremity injuries positively.
- Conditions
- Strength, Exercise, Knee Injuries
- Trial name
- NCT04815980
- Testing
- Exercise
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of the Incarnate Word
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture
Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
A potential long-term consequence of anterior cruciate ligament injuries is the development of post-traumatic osteoarthritis in the years following injury.
- Trial name
- NCT04088227
- Testing
- Experimental Group, Control Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Andrews Research & Education Foundation
Anterior Cruciate Ligament (ACL) Tear
Low Level Laser Therapy Versus Short Wave Diathermy in Patients With Anterior Cruciate Ligament Tear
This clinical research study is comparing two non-surgical treatments-Low-Level Laser Therapy (LLLT) and Short Wave Diathermy (SWD)-to see which is more effective for people with a partial tear of the anterior cruciate ligament…
- Trial name
- NCT07089459
- Testing
- Low-Level Laser Therapy (LLLT), Shortwave therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Anterior Cruciate Ligament Injury
Functional Resistance Training to Improve Knee Function After ACL Reconstruction
The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury and reconstruction can be improved with functional resistance training.
- Trial name
- NCT03282565
- Testing
- Functional Resistance Training with Brace, Control, Functional Resistance Training with Elastic Band
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
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