Clinical trials: Injuries, Knee
Anterior Cruciate Ligament Rupture
The Clinical Efficacy of Anterolateral Complex Augmentation in Patients With ACL Rupture Combined With Excessive Internal Tibial Rotation Subluxation: A Bidirectional Cohort Study
This project aims to establish a high-quality, large-scale, single-center bidirectional cohort study to evaluate the postoperative clinical efficacy of ACLR combined with ALC augmentation in a specific high-risk…
- Trial name
- NCT06961292
- Where
- China
- Volunteers
- 335 people
- Sponsor
- Peking University Third Hospital
Knee Pain, Knee Injuries
Effect of PRP Injection After Arthroscopic Meniscal Repair in the Healing Process
The investigator's hypothesis was that intra-articular knee injection with PRP in patients underwent arthroscopic meniscal repair and didn't receive intra-surgical PRP, may add beneficial effect on post-meniscal repair outcomes…
- Trial name
- KneePRP (NCT03910036)
- Testing
- platelet rich plasma
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hip Fractures, Knee Arthroplasty
Continuous Spinal Anesthesia Versus Combined Spinal Epidural Block
In major orthopaedic surgery of the lower extremities both continuous spinal anesthesia (CSA) and combined spinal epidural anesthesia (CSE) are safe and reliable anaesthesia methods.
- Conditions
- Hip Fractures, Knee Arthroplasty, Femur Fracture
- Trial name
- Spinocath (NCT00616044)
- Testing
- continuous spinal anesthesia, Spinocath a catheter for continuous spinal anesthesia, combined spinal epidural anesthesia
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Sao Jose do Rio Preto Medical School
Patella Fracture, Aging
Patella Fracture : A Randomized Controlled Trial
This is a multi-centre, randomized controlled trial comparing operative and non operative treatment for displaced patella fractures in elderly, low-demand patients.
- Trial name
- NCT03445819
- Testing
- Group A: Surgical Treatment, Group B: Conservative Treatment
- Where
- 3 sites in Canada
- Volunteers
- 84 people
- Sponsor
- Unity Health Toronto
Bone Fracture
HealthEast Community Hip and Knee Replacement Registry
HealthEast Care System began the first community-based joint replacement registry (HJRR) in the U.S. in 1991, and now has more than 30,000 total joints registered.
- Trial name
- HEJR (NCT02692092)
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- HealthEast Care System
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Arthrometry and Clinical Tests for Diagnosing ACL Tears
Anterior cruciate ligament (ACL) tears are diagnosed by combining the patient's history and physical examination but clinical tests (e.g., Lachman, anterior drawer, and pivot shift) are less accurate within the first three weeks…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05416632
- Testing
- Athrometer
- Where
- 2 sites in United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Knee Arthropathy
Laser + Cryo-thermal Therapy Following Total Knee Replacement Surgery
Objective To investigate the effectiveness of the use of the QMD Helios Laser device in association with standard rehabilitation therapy in reducing inflammatory symptoms in patients following total knee replacement.
- Trial name
- NCT04183673
- Testing
- Laser therapy-cryo thermal therapy, Usual care
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Anterior Cruciate Ligament Tear
Prospective Femoral Versus Femoral and Sciatic Nerve Block for Anterior Cruciate Ligament (ACL) Reconstruction
The investigators propose that a preoperative femoral and sciatic blocks vs a femoral block only, prior to ambulatory anterior cruciate ligament (ACL) reconstruction will lead to a decrease in opiate consumption, pain scores, and…
- Trial name
- NCT01447277
- Testing
- Sciatic Block, Femoral Block only
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of California, San Francisco
Hip Fractures (ICD-10 72.01-72.2), Osteoarthritis, Knee and Hip
Population Pharmacokinetics and Pharmacodynamics of Ciprofol
The goal of this observational study is to learn how the anesthetic drug ciprofol works in older adults who are having limb surgery under general anesthesia at Shanghai Geriatric Medical Center.
- Conditions
- Hip Fractures (ICD-10 72.01-72.2), Osteoarthritis, Knee and Hip, Femoral Neck Fractures
- Trial name
- NCT07301242
- Testing
- Ciprofol
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Geriatric Medical Center
Knee Arthropathy, Hip Arthropathy
Routine Use of Negative Pressure Wound Therapy THR TKR RCT
Negative pressure wound therapy (NPWT) for post total joint arthroplasty incisions has demonstrated benefits in reducing wound complications.
- Conditions
- Knee Arthropathy, Hip Arthropathy, Negative Pressure Wound Therapy
- Trial name
- NCT06181097
- Testing
- negative pressure wound therapy, standard dressing
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament Tear
The Effect of Perioperative and Postoperative Music Reduces Pain Perception After Anterior Cruciate Ligament Reconstruction
study the effect of music therapy in pre-operative and post operative period and measure the out come by the visual analog scale (pain score) and analgesic drug use such as morphine and the anxiety score
- Trial name
- NCT06275828
- Testing
- slow beat mesic listening by headphone
- Where
- Thailand
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Police General Hospital, Thailand
Knee Osteoarthritis
Veteran Affairs Osteoarthritis Knee Study
A clinical study at the Dallas Veterans Affairs, is being proposed to test the efficacy of a novel electrical stimulation platform named the Pro-Sport Ultra® device by AVAZZIA to reduce pain and increase activity level in…
- Trial name
- NCT04698733
- Testing
- BEST™ HVPC microcurrent electrical stimulation Pro-Sport Ultra® device
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Avazzia, Inc
Anterior Cruciate Ligament (ACL) Tear
Augmented Reality in Surgery
The goal of this observational study is to learn whether an artificial-intelligence software can reliably recognise the anatomical landmarks used to guide femoral bone tunnel placement on the arthroscopic monitor image during…
- Trial name
- ARS (NCT07636278)
- Testing
- Primary arthroscopic anterior cruciate ligament reconstruction
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
The Effectıveness Of Structured Myofascial Chain Exercise Training After Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament reconstruction(ACLR) surgery accepts best choices which condicions are totaly ruptured ACL or partial ruputures when patients with high activity level.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05423184
- Testing
- Exercise Therapy For Lower Extremities, Exercise Therapy For Myofascial Chains
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Anterior Cruciate Ligament Injury, ACL
Mechanical Perturbation Training for ACL Injury Prevention
A prospective trial will be used to evaluate the efficacy of prophylactic mechanical perturbation training program. 24 female athletes who are regular participants in activities that involve cutting, pivoting, jumping, and…
- Trial name
- NCT03080402
- Testing
- Mechanical Perturbation Training
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Anterior Cruciate Ligament Rupture
BioCleanse Tibialis Tendon Anterior Cruciate Ligament (ACL) Study
To compare the outcome of Anterior Cruciate Ligament (ACL) reconstruction performed using the tibialis allograft to historical outcomes of ACL reconstruction patients and to establish if any correlation exists between the age of…
- Trial name
- NCT00975845
- Testing
- BioCleanse Tibialis tendon
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- RTI Surgical
Arthroplasty, Knee Replacement, Wound Healing
Zip® Surgical Skin Closure Device vs. Staples for Skin Closure in Subjects Having Undergone Bilateral Knee Arthroplasty
Study designed to compare the Zip Surgical Skin Closure device vs. conventional staples for wound closure following bi lateral knee replacement surgery.
- Trial name
- NCT02460172
- Testing
- Zip Surgical Skin Closure, Steel Staples
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ZipLine Medical Inc.
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effects of Whole-body Vibration on Increasing Quadriceps Strength in Patients With ACL Ruptures
Introduction: Approximately 35% patients can not return to sports after anterior cruciate ligament reconstruction(ACLR). Persistent quadriceps weakness is a factor that prevents patients return to sports.
- Trial name
- NCT04988828
- Testing
- Whole body vibration
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
ACL Injury, ACL - Anterior Cruciate Ligament Rupture
Improving ACL Reconstruction Outcomes: CBPT
The overall objective of this study is to conduct a two-group randomized trial to examine the efficacy of cognitive-behavioral based physical therapy (CBPT) for improving knee function, return to sport, and quality of life…
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL Sprain, ACL Tear
- Trial name
- NCT03243162
- Testing
- CBPT-ACLR, Education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center
Osteoarthritis
Comparison of Two Methods of Patellar Resurfacing in Total Knee Arthroplasty
The aim of this prospective, randomized study was to compare the clinical and radiological results of "free-hand" technique and "resection guide" technique for preparing patella during total knee arthroplasty.
- Trial name
- NCT02268097
- Testing
- Patellar resurfacing with freehand technique, Patellar resurfacing with resection guide technique
- Where
- China
- Volunteers
- 101 people
- Sponsor
- Peking University Third Hospital
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