Clinical trials: Injuries
Patellofemoral Pain Syndrome, ACL Tear
Kinematic Assessment of Human Peripheral Joints by Dynamic CT
Aim of the research project: The entire research project aims to investigate human peripheral joints (knee, foot \& ankle, elbow, wrist \& hand) by dynamic 4D radiographic imaging acquisition during real-time motion.
- Trial name
- Karma-4D (NCT04732585)
- Testing
- Physiotherapy or Surgery
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Therapeutics of Bilateral Maxillofacial Injuries
Treatment of Bilateral Maxillofacial Post-traumatic Deformities
Combined application of surgery planning software and rapid prototyping technology and preshaped titanium plates can effectively promote the accuracy of the diagnosis and treatment of bilateral maxillofacial post traumatic…
- Trial name
- NCT01875887
- Testing
- rapid prototyping technology
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Death, Sudden, Cardiac, Electrocardiogram QT Prolonged
Risk of Sudden Cardiac Death in UN Athletes
The detection of sudden cardiac death risk in athletes is a topic of great relevance in the field of sports physiotherapy and physical activity.
- Conditions
- Death, Sudden, Cardiac, Electrocardiogram QT Prolonged, Athlete Heart, Athletic Injuries
- Trial name
- Suddendeath (NCT06518252)
- Where
- Colombia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Spinal Cord Injury, ALS (Amyotrophic Lateral Sclerosis)
Clinical Outcome Assessment for AT & BCI
Many individuals with severe motor impairments rely on Assistive Technologies (ATs) or Brain-Computer Interfaces (BCIs) to interact with digital devices such as their computers.
- Trial name
- NCT07407725
- Testing
- Eye Tracker, Mouth Operated Joystick, Non-invasive electroencephalogram (EEG) Headset
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Retinitis Pigmentosa, Maculopathy, Age Related
High Resolution, High-speed Multimodal Ophthalmic Imaging
Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging.
- Conditions
- Retinitis Pigmentosa, Maculopathy, Age Related, Macular Dystrophy, Macular Edema
- Trial name
- IMA-MODE (NCT04129021)
- Testing
- High-resolution retinal imaging through adaptive optics, High-resolution retinal imaging through holographic systems
- Where
- France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Needlestick Injuries
Will Adjusting the pH of Lidocaine Reduce the Pain During Injection of Local Anaesthetic?
This study will investigate the influence of adjusting the pH of lidocaine on pain during subcutaneous injection. Each participant will receive two injections on the abdomen with different pH.
- Trial name
- NCT02107716
- Testing
- Lidocaine injection with bicarbonate, lidocaine injection
- Where
- Norway
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Heat Stroke
Study of Risk Factors for the Occurrence and Severity of Exertional Heatstroke in the Military Environment
Although the circumstances of onset and management of exertional heatstroke have been identified for several years, its pathophysiology remains imperfectly understood. Exertional heatstroke is the result of both extrinsic (i.e.
- Trial name
- EXPLO-CCE (NCT04593316)
- Testing
- Saliva collection, Questionnaires, Ingestible core temperature capsule intake
- Where
- 3 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Burn (Disorder), Patient
Effect of Progressive Relaxation Exercises on Sleep, Anxiety, and Body Image in Burn Patients
The Importance of Sleep Quality, Anxiety Levels, and Body Image in Burn Patients Sleep quality, anxiety levels, and body image play a significant role in the recovery process and overall quality of life for burn patients.
- Trial name
- Burn Patients (NCT07531004)
- Testing
- Experimental Group, Progrressive relaxation egsercise
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Suicide, Trauma, Psychological
Wakȟáŋyeža (Little Holy One)
The overall goal of this study is to develop, adapt and evaluate an intergenerational prevention intervention, named "Wakȟáŋyeža (Little Holy One)," with Native American caregivers on a Northern Plains reservation and the…
- Conditions
- Suicide, Trauma, Psychological, Parenting
- Trial name
- NCT04201184
- Testing
- Newly created cultural components, adapted Family Spirit lessons, adapted CETA modules, Active nutrition control
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hip Fractures, COVID-19
Anesthesia Technique in COVID-19 Positive Hip Fracture Patients
Patients with COVID undergoing hip fracture repair have high mortality rates. If spinal anesthesia is associated with decreased rates of mortality, this study could provide hypothesis generating data for prospective studies.
- Conditions
- Hip Fractures, COVID-19, General Anesthesia, Spinal Anesthesia
- Trial name
- NCT05133648
- Testing
- Hip Fracture Surgery, COVID-19 infection
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Valgus Deformity, Not Elsewhere Classified, Knee, Injury, Knee
External vs Combined Focus Effects on Landing in Female Athletes
Female athletes are at higher risk of knee injuries, particularly non-contact anterior cruciate ligament (ACL) injuries, often caused by dynamic knee valgus during landing.
- Trial name
- NCT07367308
- Testing
- Single-Leg Drop Vertical Jump, Combined Focus of Attention Instruction, External Focus of Attention Instruction
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Wound Heal
Comparing the Effectiveness of Cyanoacrylate Tissue Adhesives and Conventional Sutures
This study compares the effectiveness of two materials used for intraoral wound closure after removal of impacted mandibular third molar tooth.
- Trial name
- NCT04898816
- Testing
- closure of wound using n- butyl 2-octyl cyanoacrylate tissue adhesive, closure of wound using braided silk suture
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Athletic Injuries
Prevention of Lower Limb and Groin Injuries: the Sport Without Injury ProgrammE (SWIPE) Football Trial
This is a three-armed intervention study that evaluates the injury preventive effects of three different training interventions in youth and adult football players.
- Trial name
- SWIPEsoccer (NCT04272047)
- Testing
- Knee Control+ program, Adductor strengthening program, Knee Control program
- Where
- Sweden
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Brain Injuries, Traumatic
Treatment and Recovery Monitoring of Post TBI Symptoms
This proposal aims to investigate the effect of a promising treatment for persistent post Traumatic Brain Injury (TBI) symptoms, and to monitor TBI patient's recovery by an objective technique along with standard clinical…
- Trial name
- NCT02426749
- Testing
- Active repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Injuries, Emergencies
Video-instructed First Aid in Emergency Medical Call Centers
Video streaming as an additional tool to telephone was introduced in some Norwegian emergency medical call centers during the spring of 2020.
- Trial name
- NCT05121649
- Testing
- Video streaming
- Where
- Norway
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Gingival Bleeding, Prosthesis Failure, Dental
Comparison of Effectiveness of Gingival Displacement Using Retraction Cord and Aluminum Chloride Gel
This study aims to compare the horizontal gingival displacement by using a retraction cord and aluminum chloride gel, and also to determine the time taken for placement and hemorrhage after the procedure by using a retraction…
- Conditions
- Gingival Bleeding, Prosthesis Failure, Dental, Tissue Injury
- Trial name
- NCT07255976
- Testing
- knitted cotton retraction cord, aluminum chloride gel
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Pressure Ulcer (PU)
The Effect of Pulse Oximeter Probe Replacement Interval on Pressure Injury Development in Intensive Care Patients
Patients admitted to intensive care units (ICUs) are at increased risk of medical device-related pressure injuries (MDRPIs) due to the prolonged use of monitoring devices.
- Trial name
- NCT07704710
- Testing
- Pulse Oximeter Probe Repositioning Every 2 Hours, Pulse Oximeter Probe Repositioning Every 4 Hours
- Where
- Turkey (Türkiye)
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- Emine Arici Parlak
Sepsis, Surgery
Inflammatory Mediators of Acute Kidney Injury in Intensive Care
Acute kidney injury (AKI) affects more than 50% of patients admitted to the intensive care unit. The most common underlying cause is sepsis. Severe AKI in combination with sepsis is associated with high mortality.
- Conditions
- Sepsis, Surgery, Acute Kidney Injury
- Trial name
- PronMed (NCT03720860)
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uppsala University
PTSD, Depression
Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care?
Evidence-based VA care is best for meeting Veterans' mental health needs, such as depression, PTSD and opioid use disorder, to prevent suicide or overdose. But some key evidence-based practices only reach 3-28% of patients.
- Conditions
- PTSD, Depression, Opioid Use Disorder
- Trial name
- NCT04208217
- Testing
- Modeling to Learn (MTL), Usual quality improvement (QI)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Orthopedic Disorders, Injury of Anterior Cruciate Ligament
Injection Pressure & Adductor Canal Block
This is a prospective, randomized, single-blinded human clinical trial that will examine how injection pressure influences the spread of a given volume of injectate in the adductor canal, during adductor canal nerve block.
- Trial name
- NCT02563990
- Testing
- High Pressure Injection, Low Pressure Injection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Miami
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