Clinical trials: Injuries
Major Depressive Disorder, Post-Traumatic Stress Disorder
Imaging SV2A in Mood Disorders
This study is designed to examine SV2A density in MDD and PTSD as a correlate of synaptic density, and to determine whether ketamine administration will reverse the synaptic loss in vivo in human subjects.
- Trial name
- NCT02734602
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Yale University
Social Functioning, Addiction, Substance
Pain Clinic Provides Public Health Safety
Chronic pain is associated with psychological disorders; which may affect a patient's socioeconomic, legal, domestic, and employment situations.
- Conditions
- Social Functioning, Addiction, Substance, Safety Issues, Road Injury
- Trial name
- NCT06076512
- Testing
- Behavioral therapy
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Distal Radius Fractures
Comparative Study Between Cannulated Screws and K-wires in the Fixation of Distal Radius Fractures
This comparative study aims to evaluate the clinical and radiological outcomes of cannulated screw fixation versus K-wire fixation in the treatment of distal radius fractures.
- Trial name
- NCT07523386
- Testing
- Cannulated screw Fixation In Treatment Of Distal Radius
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sohag University
Occupational Injuries, Occupational Diseases
RCT of TRIMOSH Module in Improving Knowledge, Attitude, and Practice Among Food Industries Workers
Introduction: The food and beverages industry contributed a significant income to Malaysia's Gross Domestic Products. The contribution is projected to swell more in the upcoming years.
- Trial name
- TRIMOSH (NCT05571995)
- Testing
- TRIMOSH
- Where
- Malaysia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Covid19, Burn Out
Burnout and Distress preventiOn With caNnabidiol in Front-line Health Care workerS deAling wIth COVID-19
The objective of this work is to monitor the level of stress and overload of a group of front-line health workers (physicians, nurses and physiotherapists) who will participate in the care of patients with COVID-19 at Hospital…
- Conditions
- Covid19, Burn Out, Post Traumatic Stress Disorder
- Trial name
- BONSAI (NCT04504877)
- Testing
- Cannabidiol
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Spinal Cord Injuries, Constipation
Use of a Prokinetic Agent as an Adjunct to Thrice Weekly Bowel Care After SCI
To measure a baseline for each subject, an abdominal x-ray (KUB) was performed, the SCI Bowel Survey and Treatment Satisfaction Questionnaire (TSQM) were administered and the subject's weight determined.
- Conditions
- Spinal Cord Injuries, Constipation, Neurogenic Bowel
- Trial name
- TWBC (NCT04671030)
- Testing
- Neostigmine and Glycopyrrolate, Iontophoresis
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Post-Traumatic Stress Disorder
Cannabinoid Control of Fear Extinction Neural Circuits in Post-traumatic Stress Disorder
The goal of this study is to look at how a type of drug called cannabinoids are related to the processing of fear signals, the experience of emotions and fear, and the pattern of activity in the brain that is involved in these…
- Trial name
- NCT02069366
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Peripheral Nerve Injury
Needle Nerve Contact in Ultrasound Guided Femoral Block
Ultrasound-guided femoral nerve block is a common regional anesthesia technique. The optimal method of needle guidance (in-plane versus out-of-plane) with regards to the block efficacy and avoidance of needle-nerve contact has…
- Trial name
- NCT01554722
- Testing
- Needle placement
- Where
- 2 sites in United States, Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Stress Disorders, Post-Traumatic
Augmenting Massed Prolonged Exposure With a Stellate Ganglion Block to Treat PTSD
This is a small, open-label treatment study that tests the potential safety and treatment effectiveness of a stellate ganglion block combined with Massed Prolonged Exposure (PE).
- Trial name
- NCT04302181
- Testing
- Ropivacaine injection
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Posttraumatic Stress Disorder
Attention Bias Modification Treatment for Warzone-Related Posttraumatic Stress Disorder (PTSD)
Veterans with Posttraumatic Stress Disorder (PTSD) will be randomly assigned to either Attention Bias Modification Treatment (ABMT) designed to reduce bias toward threat or a placebo control condition not designed to change…
- Trial name
- NCT01564667
- Testing
- Attention Bias Modification Training Protocol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Creighton University
Occupational Diseases, Work-related Injury
Effect of Passive and Active Rest Break in Musculoskeletal Complains
Work-related musculoskeletal disorders are highly disabling. Therefore, finding preventive solutions is fundamental, in order to reduce the damages to workers and society.
- Trial name
- NCT03559153
- Testing
- Shiatsu massage, Physical Exercise
- Where
- Brazil
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Universidade Cidade de Sao Paulo
Stroke, Paralysis Arm
PNS Motor Stimulation Study
Paralysis is one of the most disabling features of Spinal cord injury and stroke. In select cases, where the nerve is intact, stimulation can achieve meaningful muscle contraction e.g. to restore grip and release function.
- Conditions
- Stroke, Paralysis Arm, Spinal Cord Injury
- Trial name
- NCT07810712
- Testing
- Stimulation of the motor unit
- Where
- United Kingdom
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Walton Centre NHS Foundation Trust
Psoriasis
Study of a New Dressing for Use With Topical Medications
The purpose of this study is to determine if a new dressing designed to be used with topical medications will enhance the effects of these topical medications.
- Trial name
- NCT00234728
- Testing
- Occlusive dressing
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Teikoku Pharma USA, Inc.
Stress Disorders, Post-Traumatic, Depression
Psychological and Psychosocial Intervention With War-Affected Children
The investigators are interested in knowing whether a group-based, trauma-focused intervention (Trauma Focused Cognitive Behavioral Therapy) is superior to a more general, non trauma-focused, psychosocial intervention (Child…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Anxiety, Conduct
- Trial name
- NCT01509872
- Testing
- Trauma Focused Cognitive Behavioral Therapy, Child Friendly Space
- Where
- Republic of the Congo
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Aging Well, Walking, Difficulty
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
To test the hypothesis that home-based leg heat therapy improves functional capacity, vascular function, and exercise hyperemia in older adults.
- Conditions
- Aging Well, Walking, Difficulty, Hyperemia
- Trial name
- NCT05706181
- Testing
- Home-based leg heat therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Traumatized Permanent Anterior Teeth
Evaluation of Knowledge- Attitude- Practice (KAP) of Intern Dentists in Emergency Management of Traumatic Dental Injuries in Permanent Anterior Teeth
This study aims to evaluate knowledge, Attitude and Practice of intern dentists in emergency management of traumatic dental injuries in permanent anterior teeth in children aged from 6 to 12 years old.
- Trial name
- NCT03510819
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skin Wound, Scar, Hypertrophic
Umbilical Cord Stem Cells for Skin Grafts in Donor Site Wounds
The goal of this clinical trial is to evaluate the safety and effectiveness of human umbilical cord mesenchymal stem cell (hUCMSC) therapy in patients undergoing medium-thickness skin grafts for donor site wounds.
- Trial name
- NCT05984628
- Testing
- human umbilical cord mesenchymal stem cells, blank solvent
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Hamstring Tightness, Hamstring Injury Prevention
The Effectiveness of Muscle Energy Technique and Friction Massage in Hamstring Tightness Amongst Young Athletes of Pakistan
The ability of an individual to move smoothly depends on his flexibility, an attribute that enhances both safety and optimal physical activity.
- Trial name
- NCT03680300
- Testing
- Post Facilitation Stretch, Post Isometric Relaxation, Friction Massage
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isra University
Traumatic Brain Injury
Quantitative Automated Lesion Detection of Traumatic Brain Injury
The investigators propose to develop quantitative automated lesion detection (QALD) procedures to identify brain damage following traumatic brain injury more accurately than is possible with a normal magnetic resonance imaging…
- Trial name
- QALD (NCT01022307)
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Threat-related Sensory Cortical (SC) Disinhibition, Posttraumatic Stress Disorder (PTSD)
A Neurosensory Account of Anxiety and Stress (Study 2)
This study will take a basic neuroscience approach to investigate pathological mechanisms underlying PTSD. Additionally, the study aims to identify how Transcranial Alternating Current Stimulation (tACS) brain stimulation can…
- Trial name
- NCT07079839
- Testing
- Transcranial Alternating Current Stimulation (tACS), Transcranial Random Noise stimulation (tRNS)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
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