Clinical trials: Injuries
Spinal Cord Injury
Neuroplasticity After Spinal Cord Injury
The long-term goal is to acquire scientific knowledge that can be used to develop mechanistic-driven intervention strategies aiming at restoring upper and lower-limb motor function in individuals with cervical or thoracic spinal…
- Trial name
- NCT02446210
- Testing
- Magstim 200, Digitimer electrical stimulator
- Where
- United States
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Sunburn
The Sun Protection Effect and Efficacy in Treatment of Sunburn Using Topical Corticosteroids.
The purpose of the study is to evaluate the sun protection effect and efficacy in treatment of sunburn using topical corticosteroids in a randomised controlled and investigator blinded trial.
- Trial name
- NCT00206882
- Testing
- corticosteroids
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Acute Lung Injury
A Study to Investigate the Effects of Imatinib on Pulmonary Vascular Dysfunction in a Human Model of Lung Injury
The study is a randomized, double-blind, placebo-controlled clinical study of imatinib (as mesilate) in healthy subjects exposed inhaled lipopolysaccharide.
- Trial name
- NCT03328117
- Testing
- Imatinib
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Exvastat Ltd.
Anxiety, Posttraumatic Stress Disorder
School-based Practices in Arts and Resilience for Kids
This proposal will implement and test feasibility and efficacy of school-based art therapy and yoga/mindfulness programming to reduce mental health disparities and foster resilience in youth.
- Conditions
- Anxiety, Posttraumatic Stress Disorder, Trauma
- Trial name
- SPARK (NCT06945497)
- Testing
- Art Therapy, Yoga/Mindfulness
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Time-Loss Injury Incidence
Effects of an ACWR-Guided Load Management Intervention on Time-Loss Injury Incidence in Chinese Elite Youth Footballers: A Cluster Randomised Controlled Trial
This cluster-randomised controlled trial aims to evaluate whether a multi-component load management intervention-incorporating real-time acute:chronic workload ratio (ACWR) feedback, automated alerts, coach education, and…
- Trial name
- ACWR Injury (NCT07727382)
- Testing
- ACWR-guided load management
- Volunteers
- 847 people, healthy volunteers welcome
- Sponsor
- Xinyang Agriculture and Forestry University
Wound Heal
Study to Evaluate the Safety of FSR Peptide Versus Placebo Following Punch Biopsy
The purposes of this study is to test the safety of the study drug (FSR peptide) after a punch biopsy in healthy subjects.
- Trial name
- NCT04473859
- Testing
- FSR Peptide 20μM, FSR Peptide 50μM, FSR Peptide 100μM
- Where
- Switzerland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Xequel Bio, Inc.
Athletic Injuries
Functional and Performance Effects of a 4-week Weightlifting Program in Highly Trained Adolescent Basketball Athletes
Weightlifting is an increasingly used intervention in the sport field to improve both function and performance outcomes. However, the effects in a pediatric and adolescent population are not well described, and require further…
- Trial name
- NCT05824780
- Testing
- Exercise training
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Valencia
PTSD
Losartan and Memory
This study investigates the effect of a single dose of 50mg losartan vs placebo on BOLD signal during memory encoding.
- Trial name
- NCT05828940
- Testing
- Losartan Potassium
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Wound Care, Children Pain Management
Child's Interaction With a Social Robot During Dressing
The aim of this randomized controlled trial, consisting of 30 experimental and 30 control groups, was to examine the effect of a child's interaction with a social robot during wound dressing on their fear and pain.
- Conditions
- Wound Care, Children Pain Management, Distraction Methods, Distraction
- Trial name
- NCT07549191
- Testing
- Social Robot
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Achilles Tendon, Tendinopathy
Eccentric Training and Cryotherapy Vs Eccentric Training and Whole Body Vibration in Achilles Tendinopathy
The purpose of this study is to determine the effectiveness of eccentric exercise combined with vibration or cryotherapy in Achilles tendon pathology.
- Trial name
- NCT03029910
- Testing
- Cryotherapy and eccentric exercise, Vibration and eccentric exercise
- Where
- Spain
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Perineal Tear, Pain
The Application of Honey on Perineal Sutures
Evaluate the effect of honey on perineal tears or episiotomies pain associated or not with anterior vulvar tears after vaginal delivery.
- Conditions
- Perineal Tear, Pain, Burns
- Trial name
- NCT03670420
- Testing
- Medical honey
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Alveolar Bone Grafting, Bone Healing
Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation
The main purpose of the study is to measure and localize immediate post extraction changes i.e. socket expansion versus no width change along the socket wall and identify whether the immediate post-extraction ridge width…
- Conditions
- Alveolar Bone Grafting, Bone Healing, Tooth Extraction Site Healing, Wound Healing
- Trial name
- NCT06624982
- Testing
- observational study
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marquette University
Wounds
Efficacy Study of GLYC-101 to Evaluate Outcomes After Post-laser Ablation
Study is intended to evaluate safety and efficacy parameters in patients treated with GLYC-101 gel or placebo after laser ablation.
- Trial name
- NCT00656474
- Testing
- GLYC-101 gel (1.0 %)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- TR Therapeutics
Thoracic Aorta
Aortic Elongation and Dissection
Aim of this study is to measure length of the ascending aorta in adults and to investigate the clinical implication of 'elongation' of the aorta.
- Trial name
- NCT02722889
- Where
- Netherlands
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Burn Injury
Evaluation of Gait Symmetry in Upper Extremity Burn Injuries
Thirty patients with unilateral burn injury, and 60 healthy subjects will be included in this study. Participants with burn injury will evaluate with the following assessment tools: Demographic data; age, gender, height, body…
- Trial name
- NCT03759613
- Testing
- Gait Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Motivation, Drug Effect
How Stress Alters Opioid Drug Effects
The main objective of the study is to test the hypothesis that opioid drug effects vary as a function of pre-drug affective state.
- Conditions
- Motivation, Drug Effect, Stress Reaction, Misuse, Opioid
- Trial name
- OPIOIDREWARD (NCT06485817)
- Testing
- Oxycodone, Stress State Induction, Control State Induction
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Post-traumatic Pain
Effect of Telemedecine on Post -Trauma Pain Medication Adherence .
The impact of telemonitoring on patients' adherence to post trauma pain treatment , their satisfaction and pain relief after discharge from the ED.
- Trial name
- NCT05149417
- Testing
- SMS reminding, telemonitoring
- Where
- 2 sites in Tunisia
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Psychological Well-Being, Spinal Cord Injuries
Self-Management Program for AIS D SCI
About 25-51% of adults with acquired spinal cord injury (SCI) have "AIS D" SCI, the lowest severity grade of neurologic injury. Veterans with AIS D SCI generally have better outcomes in mobility, community integration, and…
- Trial name
- SCISM-D (NCT05800717)
- Testing
- SCI Self-Management for AIS D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Pain Response, Stress, Trauma
Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive Learning and Executive Function
The study design is to assess the between groups factor (controls, chronic pain, addicted individuals) and repeated measures factor of pain/stress (pain vs no pain) along with a longitudinal component to assess stress, pain and…
- Trial name
- NCT04419831
- Testing
- Yale Stress Pain Test (YSPT)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yale University
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
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