Clinical trials: Injury
Rotator Cuff Tear
Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells (Rotator Cuff Tear)
Main purpose of this study is to evaluate efficacy of allogenic adipose-derived mesenchymal stem cells in treatment of tendon injury.
- Trial name
- NCT02298023
- Testing
- allogenic adipose stem cell injection, fibrin glue/normal saline injection, normal saline injection
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Intra-Articular Fractures
Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures
The purpose of this study is to examine the effect of early, percutaneous, intra-articular saline lavage on the undiluted synovial fluid microenvironment during the acute phase following intra-articular fracture of the human…
- Trial name
- NCT05465382
- Testing
- Saline Lavage, No intra-articular saline lavage, Lidocaine - intra-articular injection
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Duke University
Osteoporosis
Comparison of the Effect of an Ongoing Treatment With Alendronate or a Drug Holiday on the Fracture Risk in Osteoporotic Patients With Bisphosphonate Long Term Therapy
The purpose of this study is to evaluate the efficacy and safety of bisphosphonates in long term treatment of osteoporosis.
- Trial name
- BILANZ (NCT01512446)
- Testing
- Alendronate
- Where
- Germany
- Volunteers
- 436 people
- Sponsor
- Evangelisches Krankenhaus Lutherhaus gGmbH
Infection, Spinal Injuries
The Value of Home Chlorhexidine Pre-Surgical Wash Before Spine Surgery
The study team hypothesizes that at-home cleansing of the surgical site with chlorhexidine wipes provide no added benefit to decreasing microbial activity or preventing surgical site infections.
- Trial name
- NCT02767427
- Testing
- Chlorhexidine Wipes, No intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Allergic Reaction, Wound Complication
Prineo Sensitivity Dressing Study
Wound complications can be devastating following total joint arthroplasty, resulting in an increased practice burden in the form of more frequent follow ups, increased clinic visits potential for wound dehiscence, superficial…
- Trial name
- NCT06011603
- Testing
- Prineo dressing
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Osteoporosis, Bone Diseases, Metabolic
Patient Activation After DXA Result Notification
There is growing evidence that patients undergoing bone mineral density testing (BMD) often do not take important steps to improve their bone health.
- Trial name
- PAADRN (NCT01507662)
- Testing
- Bone Mineral Density Result Letter and Bone Health Brochure
- Where
- 4 sites in United States, Canada
- Volunteers
- 7,749 people, healthy volunteers welcome
- Sponsor
- Fredric D Wolinsky
Burns
BEST (Burn Center Evaluation of Standard Therapies) Ventilator Mode Study-
The purpose of this study is to compare High Frequency Pressure Ventilation (HFPV) to conventional mechanical ventilation. Hypothesis: Patients placed on HFPV will have significantly higher number of ventilator-free days compared…
- Trial name
- NCT00351741
- Testing
- Ventilation - High Frequency Percussive Ventilation, Ventilation - ARDSnet
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- United States Army Institute of Surgical Research
Periodontitis, Wound Healing
Effectiveness of Three Different Mouthrinses in Dental Plaque Control and Early Wound Healing
Aim: This study compared the effectiveness of three different mouthrinses (alcohol and non-alcohol chlorhexidine, alkyl dimethyl glycine / alkyl dimethyl amine oxide - C31G) in plaque control and early wound healing…
- Trial name
- NCT03119831
- Testing
- Alcohol-based Chlorhexidine Gluconate 0.12%, Alcohol-free Chlorhexidine Gluconate 0.12%, C31G
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Hemianopia
Multisensory Rehabilitation of Hemianopia
The current proposal is to generate "proof of concept" evidence that hemianopia can be successfully rehabilitated in humans when this multisensory rehabilitation paradigm is used.
- Trial name
- NCT04963075
- Testing
- multisensory rehabilitation paradigm
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Wake Forest University Health Sciences
Spinal Cord Injuries
Feasibility of Mindfulness Meditation Training and Home Practice in Persons With Spinal Cord Injury
The purpose of this study is to evaluate the feasibility and acceptability of a 6-week app-guided Mindfulness meditation training (MM) intervention and health education (active control) condition in people with spinal cord injury…
- Trial name
- NCT05556057
- Testing
- mindfulness meditation(MM), Health Education (active control)
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- The University of Texas Health Science Center, Houston
Tibial Meniscus Injuries, Tibial Meniscus Tears
Success of Long-acting Anti-inflammatories After Anterior Cruciate Ligament and Meniscal Injury
The purpose of this study is to determine if extended-release triamcinolone acetonide treatment alters the progressive changes in bone shape previously demonstrated after anterior cruciate ligament (ACL) reconstruction with…
- Conditions
- Tibial Meniscus Injuries, Tibial Meniscus Tears, Tibial Meniscus, Torn, Anterior Cruciate Ligament Tear
- Trial name
- SLAM (NCT04331002)
- Testing
- Zilretta
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Austin V Stone
Family Members, Post Intensive Care Unit Syndrome
Psychological Symptoms and Families of COVID-19 Patients
Families of patients in Intensive Care Units (ICUs) are at increased risk for developing psychological symptoms that can last for months after the patient is discharged.
- Conditions
- Family Members, Post Intensive Care Unit Syndrome, Post Traumatic Stress Disorder
- Trial name
- NCT04501445
- Testing
- Written Summary of Rounds
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Rush University Medical Center
Pain
A Pilot Study of TRV130 for the Treatment of Fracture Pain
The primary objective is to evaluate the analgesic efficacy of TRV130 for moderate to severe acute pain in patients presenting to the emergency department (ED) with a suspected/known, unilateral, closed long bone fracture.
- Trial name
- NCT02520297
- Testing
- TRV130
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Trevena Inc.
Brain Injuries, Traumatic
Neuroactive Steroids and Traumatic Brain Injury (TBI) in OEF/OIF Veterans
Purpose: Mild traumatic brain injury (TBI) is extremely common among Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) era Veterans.
- Trial name
- NCT01336413
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- VA Office of Research and Development
Burn Scars
Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance
The investigators are studying the appearance and function of burn scars after treatment with fractionated carbon dioxide laser.
- Trial name
- NCT02115646
- Testing
- fractionated carbon dioxide laser
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Massachusetts General Hospital
ACL Injury
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes
Females who participate in cutting and landing sports suffer anterior cruciate ligament (ACL) injuries at a 2 to 10-fold greater rate than males participating in the same high-risk sports.
- Trial name
- NCT01034527
- Testing
- Neuromuscular Training
- Where
- United States
- Volunteers
- 593 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Traumatic Brain Injury
Transforming Research and Clinical Knowledge in TBI Pilot
The global aim of this proposal is to test and refine Common Data Elements (CDEs), neuroimaging standards, and best practices for genetics and proteomics in Traumatic Brain Injury (TBI) studies.
- Trial name
- NCT01565551
- Testing
- N/A (Observational Study)
- Where
- 4 sites in United States
- Volunteers
- 650 people
- Sponsor
- University of California, San Francisco
Palatal Wound
Clinical and Histological Outcomes of Allogenic Amnion Chorion Membrane in the Healing of Free Gingival Graft Donor Site
The purpose of this study is to compare an allogenic amnion chorion membrane to a collagen dressing in palatal wound healing after harvesting free gingival graft (FGG).
- Trial name
- NCT03713073
- Testing
- Allogenic amnion chorion membrane, Collagen dressing
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The University of Texas Health Science Center, Houston
Surgical Wound Infection, Preoperative Care
Povidone-Iodine for Nasal Decolonization
To evaluate the efficacy and tolerability of 10% povidone-iodine in eliminating nasal carriage of Staphylococcus aureus and MRSA.
- Conditions
- Surgical Wound Infection, Preoperative Care, Methicillin-Resistant Staphylococcus Aureus
- Trial name
- NCT05529173
- Testing
- Povidone-Iodine 10%, 0.9% NaCl Solution
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Rutgers, The State University of New Jersey
Chronic Traumatic Encephalopathy
18F-AV-1451 and Florbetapir F 18 PET (Positron Emission Tomography) Imaging in Subjects at Risk for Chronic Traumatic Encephalopathy
This study will explore the use of flortaucipir as a biomarker for chronic traumatic encephalopathy (CTE) and examine the relationship between clinical presentation and tau deposition.
- Trial name
- NCT02079766
- Testing
- florbetapir F 18, Flortaucipir F18
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals
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