Clinical trials: Innovative Procedures
Tobacco Dependence
Tobacco Intervention in Buprenorphine Treatment
Drug addiction treatment patients, including those in treatment for opioid dependence, have a high rate of tobacco dependence, especially cigarette smoking.
- Trial name
- IBIS (NCT01350011)
- Testing
- Innovative System, Standard Treatment Control (STC)
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cancer
E-health Intervention for Cancer Survivors
This study will develop and examine the effectiveness of an intervention that utilizes multiple telecommunications technologies to improve cancer survivors' access to mental health care and increase their ability to manage the…
- Trial name
- Onward (NCT01114802)
- Testing
- Project Onward website + social network, Project Onward website
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Northwestern University
Teen Pregnancy
Evaluation of My Future Self, an New Teen Pregnancy Prevention Group Intervention for Youth in Non-traditional Settings
Children's Hospital Los Angeles and ETR will implement and test the effectiveness of a pregnancy prevention intervention, My Future Self, targeting youth ages 16-19 in Los Angeles and San Diego Counties who, for a variety of…
- Trial name
- NCT05796687
- Testing
- My Future Self
- Where
- United States
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Liver Fibrosis
Evaluation of Innovative Ultrasonic Techniques for Non-invasive Diagnosis of Liver Fibrosis in Patients With Chronic Viral Hepatitis B or C
The non-invasive assessment of liver fibrosis in chronic viral hepatitis B and C is now entering clinical practice. It is based on blood tests, especially FibroMetre® and Fibrotest® and on elastography with the Fibroscan®.
- Trial name
- FIBRECHO (NCT01537965)
- Testing
- Fibroscan® of Echosens, Aixplorer® of Supersonic Imagine, Aplio XG of Toshiba, QRS software developed by Pr I.Bricault, Acuson S2000 of Siemens
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Grenoble
Cystic Fibrosis
Development Of An Innovative Panel of Methods To Measure Intestinal Macronutrient Digestion, Absorption, and Function
Malnutrition is a significant problem in children and adults with Cystic fibrosis (CF). An impaired intestinal digestion and absorption capacity is one of the main factors responsible for the malnutrition in CF.
- Trial name
- NCT01494909
- Testing
- Ensure plus
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
HIV Infections, AIDS
The CORE Buprenorphine Project - An HIV Primary Care Program Demonstration
The goal of this study is to develop and evaluate an innovative model of care to better serve patients who are both HIV-infected and opioid-dependent.
- Conditions
- HIV Infections, AIDS, Opiate Dependence, Post-Traumatic Stress Disorders
- Trial name
- BUP (NCT00227357)
- Testing
- On-site - buprenorphine/naloxone (Suboxone), Off-site - methadone or no agonist
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Ruth M. Rothstein CORE Center
Insurance Status/Stability
IMPACCT for Kids' Care
Health insurance is important for children. Public insurance programs are available to many children, but some families report being confused about how to get and keep this insurance.
- Trial name
- IMPACCT (NCT02298361)
- Testing
- Health insurance outreach IT tools
- Volunteers
- 27,251 people, healthy volunteers welcome
- Sponsor
- OCHIN, Inc.
Parkinson Disease
Tai Chi Intervention by Telerehabilitation
Rational : A lot of people in the province of Quebec suffer from Parkinson's disease and they are mostly vulnerable because they gradually lose their autonomy with the worsening of the disease.
- Trial name
- TeleParkinson (NCT03985631)
- Testing
- Rehabilitation intervention
- Where
- 2 sites in Canada
- Volunteers
- 2 people
- Sponsor
- Université de Sherbrooke
Orthodontic Tooth Movement, Burn Injury
Comparison of the Effectiveness of Innovative Techniques to Prevent Tissue Overheating During Corticotomy Using Smartphone-Based Thermography: Reticulated Surgical Guide vs Dynamic Navigation.
Objectives: The aim of the present split-mouth randomized clinical trial was to compare the effectiveness of two innovative corticotomy techniques, using reticulated static computer-guided surgery and dynamic computer-guided…
- Trial name
- NCT06934161
- Testing
- dynamic computer-guided Corticotomy, static computer-guided Corticotomy, smartphone-based thermography
- Where
- Italy
- Volunteers
- 4 people
- Sponsor
- University of Roma La Sapienza
Non-Small Cell Lung Cancer
Comparison of Biportal Versus Multiportal Robotic Approaches for Pulmonary Resection in NSCLC
This study compares two established robotic surgical approaches for removing lung tumors in adults with non-small cell lung cancer: biportal robotic-assisted thoracic surgery (biRATS) and multiportal robotic-assisted thoracic…
- Trial name
- EC-UMUR (NCT07818135)
- Testing
- Biportal Robotic-Assisted Thoracic Surgery, Multiportal Robotic-Assisted Thoracic Surgery
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Carlos Déniz
Sleep Quality
Mitigation of Health Effects in Pregnant Women by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED CLIM PW (NCT07609433)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 3 sites in Cyprus, Italy
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Underweight Children Aged 6-23 Month Old (WAZ < -1)
Innovative Nutrition and mHealth Evidence Building Project
The project is the collaboration with the lead agencies National Institute of Public Health, World Vision and Emory University World Vision has a history of successfully implementing "Positive Deviance/Hearth (PDH)" programs…
- Trial name
- NCT03399058
- Testing
- Group 1 5+5+5 (Control), Group 2: 5+5+5 & PDH, Group 3: 5+5+5 & PDH lite+mHealth
- Where
- 3 sites in Cambodia
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- National Institute of Public Health, Cambodia
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Edentulous
Guided Surgery Versus Sinus Graft
The objective of this study is to compare two surgical procedure to place implant in severely resorbed posterioir part of the maxilla.
- Trial name
- SINIMAGE (NCT01988480)
- Testing
- Image-guided surgery, Sinus lift surgery
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Smokeless Tobacco Cessation
Addressing Tobacco Use Disparities Through an Innovative Mobile Phone Intervention
The purpose of this study is to evaluate the feasibility, acceptability and preliminary efficacy of a Scheduled Gradual Reduction (SGR) intervention via Short Message Service (SMS) text messaging plus SMS Support Messages in…
- Trial name
- NCT02613689
- Testing
- Scheduled Gradual Reduction (SGR), Text Messages
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Duke University
Chest Wall Tumor
Innovative Approaches to Chest Wall Reconstruction: A Comparative Study of Rigid and Flexible Techniques
Chest wall resections, often performed for tumors, infections, or trauma, result in significant defects that require reconstruction to restore structural integrity and functionality.
- Trial name
- NCT07167810
- Testing
- bone cement, steel wires
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- University of Health Sciences Lahore
Anxiety, Pain
An Innovative Tailored Intervention for Improving Children's Postoperative Recovery (WebTIPS)
The goal of this randomized trial is to examine the effectiveness of a tailored Internet-based Preparation Program (WebTIPS) in reducing anxiety and improving the recovery process in children undergoing surgery.
- Conditions
- Anxiety, Pain, Postoperative Behavior
- Trial name
- WebTIPS (NCT03730259)
- Testing
- Web-based Tailored Intervention Preparation for Surgery
- Where
- 2 sites in United States
- Volunteers
- 1,274 people
- Sponsor
- University of California, Irvine
Poor Performance Status
Innovative Training Methods for Frail Elderly in the Training Gain Stage
This study aims to examine long term effects in the training gain stage of the falls management exercise programs (FaME, from Skelton and Dinan) over 10 weeks on physical functional performance after mechanical SR-WBV, dance…
- Trial name
- NCT01713790
- Testing
- Stochastic resonance whole-body vibration, Exergame, Leg press
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults
The StayFitLonger Study: an Innovative Computerized Home-based Training to Foster Independent Life at Home
Multimodal training, including physical and cognitive activities, has been associated with a reduction in age-related physical and cognitive decline.
- Conditions
- Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults, Physical Decline Prevention in Robust Older Adults, Physical Decline Prevention in Pre-frail Older Adults
- Trial name
- SFL (NCT04237519)
- Testing
- SFL training, Active controlled training
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Multiple Chronic Conditions, Disability Physical
Behavioral Activation + Occupational Therapy
Approximately 45% of older adults in the U.S. have 2 or more chronic health conditions (e.g., arthritis, hypertension, diabetes) in addition to functional limitations that prevent performance of health self-management activities.
- Trial name
- BA+OT (NCT05600465)
- Testing
- Behavioral Activation + Occupational Therapy, Enhanced Usual Care
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Oklahoma